Patent Application
20220280769
n/a.
The present technology is generally related to implantable blood pumps, and in particular, implantable blood pumps with a minimal hemolysis impeller.
Implantable blood pumps are commonly used to assist the pumping action of a failing heart and typically include a housing with an inlet, an outlet, and a rotor mounted therein. The inlet may be connected to a chamber of the patient's heart, typically the left ventricle, using an inflow cannula. The outlet may be connected to an artery, such as the aorta. Rotation of the rotor drives blood from the inlet towards the outlet and thus assists blood flow from the chamber of the heart into the artery. A known type of blood pump is a ventricular assist device (“VAD”) with examples including, but not limited to, the HVAD® pump and the MVAD® pump manufactured by HeartWare, Inc. in Miami Lakes, Fla., USA.
Current VADs have rotors with a plurality of blades configured to impel blood downstream from the inlet. However, these blades are static in that they have a single shape and profile during the pumping of blood.
The techniques of this disclosure generally relate to an implantable blood pump impellers.
In one aspect, the present disclosure provides an implantable blood pump including an impeller, at least a portion of the impeller being composed of a metal alloy that is a solid at normal body temperature and is configured to phase change to a liquid between a predetermined temperature above normal body temperature and about 40 degrees Celsius.
In another aspect of this embodiment, the impeller includes a plurality of blades, and wherein the metal alloy is included within at least one of the plurality of blades.
In another aspect of this embodiment, at least one of the plurality of blades includes a flexible material, and wherein the metal alloy is disposed within the flexible material.
In another aspect of this embodiment, the flexible material is a titanium alloy.
In another aspect of this embodiment, the flexible material is a polymer.
In another aspect of this embodiment, during a phase change of the metal alloy to a liquid, the metal alloy causes extension of the flexible material of the at least one of the plurality of blades a distance away from the impeller.
In another aspect of this embodiment, a heating element is coupled to the impeller, wherein the heating element is configured to heat the metal alloy above normal body temperature.
In another aspect of this embodiment, the metal alloy is configured to phase change from a liquid to a solid at about normal body temperature.
In another aspect of this embodiment, a cooling element is coupled to the impeller, wherein the cooling element is configured to cool the metal alloy from temperatures above normal body temperature to normal body temperature.
In another aspect of this embodiment, the pump defines a major longitudinal axis, and wherein the impeller is configured to impel blood along the major longitudinal axis.
In one aspect, an implantable blood pump system includes an impeller, at least a portion of the impeller being composed of a metal alloy that is a solid at normal body temperature and is configured to phase change to a liquid between a predetermined temperature above normal body temperature and about 40 degrees Celsius. A heating element or a cooling element is coupled to the impeller. A controller is in communication with the impeller and with the heating element or the cooling element, the controller being configured to activate the heating element or the cooling element to control a temperature of the metal alloy.
In another aspect of this embodiment, the impeller includes a plurality of blades, and wherein the metal alloy is included within at least one of the plurality of blades.
In another aspect of this embodiment, at least one of the plurality of blades includes a flexible material, and wherein the metal alloy is disposed within the flexible material.
In another aspect of this embodiment, the flexible material is a titanium alloy.
In another aspect of this embodiment, the flexible material is a polymer.
In another aspect of this embodiment, during a phase change of the metal alloy to a liquid, the metal alloy causes extension of the flexible material of the at least one of the plurality of blades a distance away from the impeller.
In another aspect of this embodiment, the pump defines a major longitudinal axis, and wherein the impeller is configured to impel blood along the major longitudinal axis.
In another aspect of this embodiment, a temperature sensor is coupled to the impeller.
In another aspect of this embodiment, the metal alloy is configured to phase change from a liquid to a solid at about normal body temperature.
In one aspect, an impeller included, at least a portion of the impeller comprising a metal alloy that is a solid at normal body temperature and is configured to phase change to a liquid between a predetermined temperature above normal body temperature and about 40 degrees Celsius.
The details of one or more aspects of the disclosure are set forth in the accompanying drawings and the description below. Other features, objects, and advantages of the techniques described in this disclosure will be apparent from the description and drawings, and from the claims.
A more complete understanding of the present invention, and the attendant advantages and features thereof, will be more readily understood by reference to the following detailed description when considered in conjunction with the accompanying drawings wherein:
It should be understood that various aspects disclosed herein may be combined in different combinations than the combinations specifically presented in the description and accompanying drawings. It should also be understood that, depending on the example, certain acts or events of any of the processes or methods described herein may be performed in a different sequence, may be added, merged, or left out altogether (e.g., all described acts or events may not be necessary to carry out the techniques). In addition, while certain aspects of this disclosure are described as being performed by a single module or unit for purposes of clarity, it should be understood that the techniques of this disclosure may be performed by a combination of units or modules associated with, for example, a medical device.
In one or more examples, the described techniques may be implemented in hardware, software, firmware, or any combination thereof. If implemented in software, the functions may be stored as one or more instructions or code on a computer-readable medium and executed by a hardware-based processing unit. Computer-readable media may include non-transitory computer-readable media, which corresponds to a tangible medium such as data storage media (e.g., RAM, ROM, EEPROM, flash memory, or any other medium that can be used to store desired program code in the form of instructions or data structures and that can be accessed by a computer).
Instructions may be executed by one or more processors, such as one or more digital signal processors (DSPs), general purpose microprocessors, application specific integrated circuits (ASICs), field programmable logic arrays (FPGAs), or other equivalent integrated or discrete logic circuitry. Accordingly, the term “processor” as used herein may refer to any of the foregoing structure or any other physical structure suitable for implementation of the described techniques. Also, the techniques could be fully implemented in one or more circuits or logic elements.
Referring now to the drawings in which like reference designators refer to like elements there is shown in
Referring now to
In one configuration, a heating element 36, such as a resistive heating element may be coupled to or other positioned on or proximate to the metal alloy 32. The heating element 36 maybe in communication with the controller 18, which is configured to modulate the heat generated by the heating element 36 to control the phase change of the metal alloy 32. A temperature sensor 37 may also be included on one of the impeller blades 30 and in further communication with the controller 18. The controller 18 may be configured to modulate the heating element 36 at preset times, for example, every hour on the hour, to cause a phase change of the metal alloy 32. Power for the heating element may supplied by kinetic energy harvesting components as the impeller 12 rotates as disclosed in U.S. patent application Ser. No. 16/952,613, the entirety of which is expressly incorporated by reference herein. Similarly, a cooling element 38, for example a Peltier cooling element, may be coupled or otherwise positioned on or proximate to the metal alloy 32. The cooling element 38 may be powered in a similar manner to that of the heating element 36 and is configured to cool the metal alloy 32 from its liquid state back to its solid state, that is, from temperatures above normal body temperature back to normal body temperature. In one configuration, the controller 18 controls the operation of both the heating element 36 and cooling element 38 by communicating with a wireless transmitter (not shown) on the impeller 12 as part of the kinetic energy harvesting components. In other configurations, the metal alloy 32 may be disposed within the inflow cannula of the pump 10. For example, in a first configuration the inflow cannula may include the metal alloy 32 in a solid configuration, and then when heated, the inflow cannula contracts the lumen within the inflow cannula to prevent retrograde flow. Details about the contraction of the inflow cannula may be found in U.S. patent application Ser. No. 17/100,319, the entirety of which is expressly incorporated by reference herein.
It will be appreciated by persons skilled in the art that the present invention is not limited to what has been particularly shown and described herein above. In addition, unless mention was made above to the contrary, it should be noted that all of the accompanying drawings are not to scale. A variety of modifications and variations are possible in light of the above teachings without departing from the scope and spirit of the invention, which is limited only by the following claims.
