This application claims priority from prior Japanese Patent Application No. 2016-191450 filed with the Japan Patent Office on Sep. 29, 2016, the entire contents of which are incorporated herein by reference.
The disclosure relates a blood sample testing apparatus and a blood sample testing method of performing sample measuring and preparation of a smear.
Japanese Patent Application Publication No. 2013-210266 (Patent Literature 1) discloses a sample processing system in which sample analyzer 901 and smear preparing apparatus 902 are connected to each other by supply line 903 (hatched section) as illustrated in
In a sample test, a retest, which is second or subsequent sample measurement, is performed in some cases, such as in a case where an abnormal value of a certain sample is obtained in an initial test, which is first sample measurement. In the sample processing system of Patent Literature 1, after all kinds of sample measurement including the initial test and the retest are completed for all of the test target sample containers held by rack 904, rack 904 is transported from sample analyzer 901 to smear preparing apparatus 902.
In Patent Literature 1 described above, the smear preparation in the smear preparing apparatus is started after all the kinds of test measurement including the initial test and the retest are executed on all the sample containers held by the rack. Therefore, a standby time of the smear preparing apparatus increases, and it takes a long time to perform entire sample test processing including the sample measurement and the smear preparation. Therefore, it is desired to reduce a processing time required for the sample test processing including the sample measurement and the smear preparation.
According to one or more embodiments may reduce the processing time required for the sample test processing including the sample measurement and the smear preparation.
A blood sample testing apparatus according to one or more embodiments may include: a blood-cell-count measurement unit that performs measurement of a blood sample stored in a sample container positioned in a first position; a smear preparation unit that prepares a smear of the blood sample stored in the sample container positioned in a second position; and a transport unit that transports the sample container from the first position to the second position and from the second position to the first position.
A blood sample testing method according to one or more embodiments may include: transporting a sample rack that holds sample containers to a first position and performing blood-cell-count measurement of a blood sample stored in a sample container; transporting the sample rack from the first position to the second position and preparing a smear of a blood sample stored in a sample container; and transporting the sample rack from the second position to the first position and performing blood-cell-count measurement of a blood sample stored in a sample container.
Blood sample testing apparatus 100 according to a first aspect includes blood-cell-count measurement unit 10 that performs measurement of a blood sample stored in sample container 80 positioned in first position 91, smear preparation unit 20 that prepares a smear of the blood sample stored in sample container 80 positioned in second position 92, and transport unit 30 capable of transporting sample container 80 from first position 91 to second position 92 and from second position 92 to first position 91.
In blood sample testing apparatus 100 according to a first aspect, as explained above, transport unit 30 capable of transporting sample container 80 from first position 91 to second position 92 and from second position 92 to first position 91 is provided. Consequently, sample container 80 can be reciprocated between first position 91 of blood-cell-count measurement unit 10 and second position 92 of smear preparation unit 20. Therefore, sample container 80 can be transported to smear preparation unit 20 before sample measurement for all of sample containers 80 is completed in blood-cell-count measurement unit 10. As a result, it is possible to reduce a processing time required for sample test processing including the sample measurement and smear preparation.
In blood sample testing apparatus 100 according to a first aspect, it may be preferable that transport unit 30 includes belt unit 31 capable of transporting sample container 80 in a forward direction from first position 91 to second position 92 and in a backward direction from second position 92 to first position 91. If blood sample testing apparatus 100 is configured in this way, it is possible to reciprocate sample container 80 between first position 91 and second position 92 with a simple configuration by the belt transport.
In this case, it may be preferable that belt unit 31 includes first belt 31a and second belt 31b capable of transporting sample container 80 in the forward direction and in the backward direction, respectively. If blood sample testing apparatus 100 is configured in this way, it is possible to independently reciprocate, with first belt 31a and second belt 31b, sample container 80 between first position 91 and second position 92.
In blood sample testing apparatus 100 according to a first aspect, it may be preferable that transport unit 30 transports sample rack 81 capable of holding multiple sample containers 80, to thereby transport sample containers 80 held by sample rack 81 to first position 91 and second position 92. If blood sample testing apparatus 100 is configured in this way, even when sample containers 80 are reciprocated between first position 91 and second position 92, it is possible to transport sample containers 80 in units of sample rack 81 unlike a case in which sample containers 80 are transported one by one. Therefore, it is possible to simplify transport processing.
In this case, it may be preferable that blood sample testing apparatus 100 includes control unit 41 that causes transport unit 30 to transport first sample container 80 held by sample rack 81 to first position 91 and thereafter transport second sample container 80 held by sample rack 81 to second position 92 before collecting first sample container 80 into sample rack 81. If blood sample testing apparatus 100 is configured in this way, even while first sample container 80 is transported to blood-cell-count measurement unit 10 and the sample measurement is performed, it is possible to transport second sample container 80 to smear preparation unit 20 and start the smear preparation. As a result, it is possible to further reduce the processing time required for the sample test processing.
In the configuration in which second sample container 80 held by sample rack 81 are transported to second position 92 before first sample container 80 is collected in sample rack 81, it may be preferable that control unit 41 causes transport unit 30 to transport second sample container 80 to second position 92 and thereafter collect first sample container 80 in sample rack 81 from first position 91 before collecting second sample container 80 in sample rack 81. If blood sample testing apparatus 100 is configured in this way, even after second sample container 80 is transported to smear preparation unit 20, it is possible to collect first sample container 80 from blood-cell-count measurement unit 10 before collecting second sample container 80 into sample rack 81 and transport next sample container 80 to blood-cell-count measurement unit 10. As a result, during processing in one of blood-cell-count measurement unit 10 and smear preparation unit 20, it is possible to continuously carry out an operation for transporting sample containers 80 to the other unit and start processing. Therefore, it is possible to further reduce the processing time required for the sample test.
In the configuration in which transport unit 30 transports sample rack 81, it may be preferable that blood sample testing apparatus 100 includes control unit 41 that selects which of first position 91 and second position 92 sample container 80 for which measurement of an initial test is already performed by blood-cell-count measurement unit 10 is to be first transported to. If blood sample testing apparatus 100 is configured in this way, transport order is not fixed. Therefore, for example, in a case where both of a retest and the smear preparation are performed, it is possible to select blood-cell-count measurement unit 10 or smear preparation unit 20, to which sample containers 80 can be transported more quickly, and transport sample containers 80. As a result, it is possible to further reduce the processing time required for the sample test.
In this case, it may be preferable that control unit 41 causes transport unit 30 to transport sample container 80, for which the initial test by blood-cell-count measurement unit 10 is performed, to first position 91 or to second position 92, to which a transport distance of sample rack 81 is shorter. If blood sample testing apparatus 100 is configured in this way, it is possible to reduce a time required for the transport of sample rack 81. Therefore, it is possible to reduce a standby time of blood-cell-count measurement unit 10 or smear preparation unit 20, which is a transport destination. As a result, it is possible to further reduce the processing time required for the sample test.
In the configuration in which it is selected which of first position 91 and second position 92 sample container 80 is to be first transported, in a case where both of a retest order and a smear preparation order are set for sample container 80 for which the measurement of the initial test is already performed, it may be preferable that control unit 41 causes transport unit 30 to transport sample container 80 in either one of first transport of transporting sample container 80 first to first position 91 and then to second position 92 and second transport of transporting sample container 80 first to second position 92 and then to first position 91. If blood sample testing apparatus 100 is configured in this way, when the same sample container 80 is to be transported to both of blood-cell-count measurement unit 10 and smear preparation unit 20, it is possible to transport sample container 80 to the positions in the order in which the standby time is shorter and sample container 80 can be processed more quickly. As a result, it is possible to further reduce the processing time required for the sample test.
In this case, it may be preferable that, in a condition in which a transport distance of sample rack 81 to first position 91 is shorter than a transport distance of sample rack 81 to second position 92 and blood-cell-count measurement unit 10 is usable to measure a sample, control unit 41 selects the first transport. If blood sample testing apparatus 100 is configured in this way, it is possible to reduce a time required for the transport of sample rack 81 and carry out the sample measurement immediately after the transport. Therefore, it is possible to further reduce the processing time required for the sample test by selecting the first transport.
In the configuration in which control unit 41 performs the control for transporting sample rack 81 in either one of the first transport and the second transport, it may be preferable that, in a condition in which a transport distance of sample rack 81 to second position 92 is shorter than a transport distance of sample rack 81 to first position 91 and smear preparation unit 20 is usable to prepare a smear, control unit 41 selects the second transport. If blood sample testing apparatus 100 is configured in this way, it is possible to reduce a time required for the transport of sample rack 81 and carry out the smear preparation immediately after the transport. Therefore, it is possible to further reduce the processing time required for the sample test by selecting the second transport.
In blood sample testing apparatus 100 according to a first aspect, it may be preferable that smear preparation unit 20 prepares a smear under a smearing condition depending on a measurement result of the sample by blood-cell-count measurement unit 10, and blood sample testing apparatus 100 includes control unit 41 that performs, when a smear preparation order is set based on the measurement result of the sample, control for starting transport of sample containers 80 to second position 92 after blood-cell-count measurement unit 10 generates the measurement result of the sample. If blood sample testing apparatus 100 is configured in this way, it is possible to prepare a high-quality smear under appropriate smearing conditions corresponding to a state of the sample grasped from the measurement result. Even in this case, while initial test measurement of sample containers 80 held by sample rack 81 is performed, it is possible to transport sample containers 80 after the generation of the measurement result to smear preparation unit 20. Therefore, it is possible to reduce the processing time required for the sample test while securing the quality of a smear.
In this case, it may be preferable that, in a condition in which a smear preparation order is set in advance before the measurement of the sample, control unit 41 starts the transport of sample containers 80 to second position 92 before blood-cell-count measurement unit 10 generates the measurement result of the sample. In a condition in which the smear preparation order is set in advance, if the measurement result of the sample is generated by a point in time when the preparation of a smear is started in smear preparation unit 20, it is possible to prepare a smear under appropriate smearing conditions. Therefore, in a condition in which the smear preparation order is set in advance, by making it possible to start the transport of sample containers 80 before the generation of the measurement result of the sample, it is possible to further reduce the processing time required for the sample test.
In the configuration in which transport unit 30 transports sample rack 81, it may be preferable that blood sample testing apparatus 100 includes control unit 41 that causes transport unit 30 to transport sample containers 80 held by sample rack 81 to first position 91 and second position 92 in a certain order, and control unit 41 causes transport unit 30 to transport sample rack 81 preferentially to first position 91 or to second position 92, to which a transport distance of sample rack 81 is shorter. If blood sample testing apparatus 100 is configured in this way, it is possible to reduce a time required for executing respective kinds of transport processing. Therefore, it is possible to prevent a standby time for transport waiting from occurring in blood-cell-count measurement unit 10 and smear preparation unit 20. As a result, it is possible to effectively reduce the processing time required for the sample test.
In this case, it may be preferable that control unit 41 causes transport unit 30 to transport sample rack 81 depending on their respective operation states of blood-cell-count measurement unit 10 and smear preparation unit 20. If blood sample testing apparatus 100 is configured in this way, it is possible to efficiently select processable transport processing depending on the operation states of blood-cell-count measurement unit 10 and smear preparation unit 20. As a result, it is possible to prevent the transport of sample rack 81 from being stopped by a processing wait of blood-cell-count measurement unit 10 and smear preparation unit 20. Therefore, it is possible to improve efficiency of the transporting operation and effectively reduce the processing time required for the sample test.
In the configuration in which transport unit 30 transports sample rack 81, it may be preferable that blood-cell-count measurement unit 10 and smear preparation unit 20 each include gripping unit 11a that grips each of sample containers 80 held by sample rack 81 and aspirator 11 or 21 that aspirates the sample stored in each of sample containers 80. If blood sample testing apparatus 100 is configured in this way, blood-cell-count measurement unit 10 and smear preparation unit 20 can have a common structure for aspirating the sample from sample container 80. Therefore, it is possible to simplify the apparatus configuration.
In this case, it may be preferable that gripping unit 11a grips sample container 80 held by sample rack 81 on transport unit 30. If blood sample testing apparatus 100 is configured in this way, sample container 80 held by sample rack 81 transported by transport unit 30 can be gripped by gripping unit 11a. Therefore, it is possible to surely aspirate the sample.
In the configuration in which transport unit 30 transports sample rack 81, it may be preferable that blood sample testing apparatus 100 includes sample-rack supply unit 32 that supplies sample rack 81 to transport unit 30 and sample-rack collection unit 33 that collects sample rack 81 from transport unit 30. If blood sample testing apparatus 100 is configured in this way, it is possible to collect sample rack 81, for which all kinds of sample test processing are completed, from transport unit 30 to sample-rack collection unit 33 and to quickly supply the next sample rack 81 from sample-rack supply unit 32 to transport unit 30. As a result, it is possible to effectively reduce the processing time required for the sample test.
A blood sample testing method according to a second aspect includes transporting sample rack 81 which holds sample containers 80 to first position 91 and performing blood-cell-count measurement of blood samples stored in sample containers 80, transporting sample rack 81 from first position 91 to second position 92 and preparing smears of blood samples stored in sample containers 80, and transporting sample rack 81 from second position 92 to first position 91 and performing the blood-cell-count measurement of blood samples stored in sample containers 80.
In the blood sample testing method according to a second aspect, since the blood sample testing method is configured as explained above, by reciprocating sample rack 81 between first position 91 for performing the blood-cell-count measurement and second position 92 for performing the preparation of the smear, it is possible to transport sample container 80 to second position 92 and start the smear preparation before the blood-cell-count measurement for all of sample containers 80 is completed. As a result, it is possible to reduce processing time require for sample test processing including the sample measurement and the smear preparation.
In the blood sample testing method according to a second aspect, it may be preferable that the blood sample testing method further includes performing the blood-cell-count measurement on the blood sample stored in first sample container 80 held by sample rack 81 transported to first position 91 and transporting, before first sample container 80 is collected into sample rack 81 at first position 91, sample rack 81 to second position 92 and performing preparation of a smear of the blood sample stored in second sample container 80 held by sample rack 81. If the blood sample testing method is configured in this way, even during the blood-cell-count measurement for the blood sample in first sample container 80 in first position 91, it is possible to transport second sample container 80 to second position 92 and start the smear preparation. As a result, it is possible to further reduce the processing time required for the sample test processing.
According to one or more aspects, it may be possible to reduce the processing time required for the sample test processing including the sample measurement and smear preparation.
Embodiments are explained below with reference to drawings.
(Overall Configuration of a Blood Sample Testing Apparatus)
An overall configuration of blood sample testing apparatus 100 according to one or more embodiments is explained with reference to
In blood sample testing apparatus 100, blood-cell-count measurement unit 10 and smear preparation unit 20 are disposed side by side in a predetermined direction. Transport unit 30 transports sample containers 80 along the predetermined direction. In the following explanation, an X direction in which blood-cell-count measurement unit 10 and smear preparation unit 20 are arranged is referred to as left-right direction, a Y direction orthogonal to the X direction is referred to as front-rear direction, and a Z direction (see
The sample is a biological specimen sampled from a subject and is, for example, blood. Sample container 80 is a tubular container opened at the upper end such as a blood collection tube. The sample is stored inside sample container 80. Sample container 80 is a cylindrical container formed by glass, synthetic resin, or the like having translucency.
Blood-cell-count measurement unit 10 performs measurement of the blood sample stored in sample containers 80. Measurement items of the sample are not particularly limited. In a configuration example illustrated in
Blood-cell-count measurement unit 10 includes aspirator 11, specimen preparation unit 12, and detection unit 13. Aspirator 11 aspirates the sample from sample container 80. Specimen preparation unit 12 prepares a specimen for detection from the sample aspirated by aspirator 11. Detection unit 13 detects a measurement target component from the specimen for detection prepared by specimen preparation unit 12. In the configuration example illustrated in
Aspirator 11 can take sample container 80, which is transported to a taking-in position on belt unit 31 of transport unit 30, into the inside of blood-cell-count measurement unit 10 and aspirate the sample stored in sample container 80. The taking-in position of blood-cell-count measurement unit 10 is first position 91 in
Specimen preparation unit 12 is connected to, in terms of fluid, reagent containers 12a in which various reagents such as a staining reagent, a hemolytic agent, and a diluent are stored. Specimen preparation unit 12 supplies the respective reagents and the sample aspirated by aspirator 11 to a not-illustrated reaction chamber and mixes and agitates the reagents and the sample, thereby preparing a specimen for detection suitable for the detection by detection unit 13.
Detection unit 13 performs component detection of measurement items from the specimen for detection prepared by specimen preparation unit 12. For example, detection unit 13 can perform RBC (red blood cell) detection and PLT (platelet) detection according to sheath flow DC detection method. Detection unit 13 performs, for example, HGB (hemoglobin) detection according to an SLS-hemoglobin method. Detection unit 13 performs, for example, detection of a WBC (white blood cell), a NEUT (neutrophil), an LYMPH (lymphocyte), an EO (eosinophil), a BASO (basophil), and an MONO (monocyte) according to a flow cytometry method in which a semiconductor laser is used. A detection result obtained by detection unit 13 is transmitted to information processing apparatus 40 as measurement data of the sample. Information processing apparatus 40 performs analysis processing of the measurement data obtained by detection unit 13, whereby numerical value data of the measurement items is obtained as a measurement result.
Smear preparation unit 20 can prepare a smear of a sample stored in sample container 80. Smear preparation unit 20 includes aspirator 21 that aspirates the sample in sample container 80, smearing unit 22 that drips the sample on the surface of slide glass 85 and smearing the sample, and staining unit 23 that stains the sample with a staining solution. Consequently, smear preparation unit 20 prepares a smear for a microscopic test.
Aspirator 21 has substantially the same configuration as aspirator 11 of blood-cell-count measurement unit 10. That is, aspirator 21 includes gripping unit 11a, container transfer unit 11b, and aspiration tube 11c. A taking-in position where aspirator 21 takes sample container 80 into smear preparation unit 20 is second position 92 illustrated in
Smearing unit 22 performs smearing processing for smearing the sample on the surface of slide glass 85 (see
Staining unit 23 brings the staining solution into contact with slide glass 85 on which the sample is smeared and dried and stains the smeared sample. Staining unit 23 performs staining processing by, for example, storing the staining solution in a not-illustrated staining tank and immersing slide glass 85, on which the sample is smeared, in the staining solution in the staining tank.
Smear preparation unit 20 includes control unit 24 capable of communicating with information processing apparatus 40. Control unit 24 is configured by a control board or the like for controlling smear preparation unit 20.
Transport unit 30 is configured to be capable of transporting sample container 80 from first position 91 to second position 92 and from second position 92 to first position 91. Consequently, since it is possible to reciprocate sample rack 81 between blood-cell-count measurement unit 10 and smear preparation unit 20, it is possible to transport sample container 80 to smear preparation unit 20 before the sample measurement for all of sample containers 80 held by sample rack 81 is completed in blood-cell-count measurement unit 10. As a result, it is possible to reduce a processing time required for the sample test processing including the sample measurement and the smear preparation.
Transport unit 30 transports sample rack 81, which can hold sample containers 80, thereby transporting sample containers 80 held by sample rack 81 to first position 91 and to second position 92. Sample rack 81 holds sample containers 80 arranged in a predetermined direction. In
In the configuration example illustrated in
Belt unit 31 is linearly formed along an array direction (the X direction) of blood-cell-count measurement unit 10 and smear preparation unit 20. Belt unit 31 is configured to be capable of linearly moving sample rack 81 in both the forward and backward directions along belt unit 31. That is, transport unit 30 can transport sample rack 81 in both directions of the X1 direction and the X2 direction on belt unit 31.
Transport unit 30 includes sample-rack supply unit 32 that supplies sample rack 81 to transport unit 30 and sample-rack collection unit 33 that collects sample rack 81 from transport unit 30. Consequently, it is possible to collect sample rack 81, for which all kinds of sample test processing are completed, from transport unit 30 to sample-rack collection unit 33 and quickly supply the next sample rack 81 from sample-rack supply unit 32 to transport unit 30. As a result, it is possible to effectively reduce the processing time required for the sample test.
Sample rack supply unit 32 can supply sample rack 81, which holds sample containers 80 that store the sample before the sample measurement and the smear preparation are carried out, to belt unit 31. Sample-rack collection unit 33 can collect sample rack 81 that holds sample containers 80, which stores the sample after the sample measurement and the smear preparation are carried out. Sample-rack supply unit 32 feeds sample rack 81 to one end portion (an X1-side end portion) of belt unit 31. Sample-rack collection unit 33 collects sample rack 81 from the other end portion (an X2-side end portion) of belt unit 31. Therefore, in belt unit 31, the one end portion (the X-1 side end portion) side is an upstream side and the other end portion (the X-2 side end portion) side is a downstream side. Blood-cell-count measurement unit 10 is disposed on the upstream side of belt unit 31 with respect to smear preparation unit 20. Smear preparation unit 20 is disposed on the downstream side of belt unit 31 with respect to blood-cell-count measurement unit 10.
Information processing apparatus 40 is configured from, for example, a PC (Personal Computer) electrically connected to blood-cell-count measurement unit 10, smear preparation unit 20, and transport unit 30. Information processing apparatus 40 is connected to host apparatus 50 such as a host computer. Information processing apparatus 40 includes control unit 41 that performs control of the transport of sample rack 81 by transport unit 30. Control unit 41 is configured as, for example, a function realized by information processing apparatus 40, which is the PC, executing a computer program for transport control.
Information processing apparatus 40 acquires a measurement order and smear preparation order for samples from host apparatus 50. Information processing apparatus 40 transmits the acquired measurement order to blood-cell-count measurement unit 10 and causes blood-cell-count measurement unit 10 to perform measurement processing based on the measurement order. Information processing apparatus 40 transmits the acquired smear preparation order to smear preparation unit 20 and causes smear preparation unit 20 to perform the smear preparation according to the smear preparation order. Information processing apparatus 40 acquires measurement data of the sample from blood-cell-count measurement unit 10 and performs necessity determination of a retest and necessity determination of smear preparation based on the measurement data.
(Transport Unit)
As illustrated in
In a configuration example illustrated in
In the configuration example illustrated in
When sample container 80 is transported to blood-cell-count measurement unit 10, transport unit 30 transports sample rack 81 such that measurement target sample container 80 is disposed in first position 91 on the upstream side on belt unit 31. First position 91 is a taking-in position of sample container 80 by blood-cell-count measurement unit 10. Blood-cell-count measurement unit 10 takes out sample container 80 transported to first position 91 and perform the sample test.
When transporting sample container 80 to smear preparation unit 20, transport unit 30 transports sample rack 81 such that smear preparation target sample container 80 is disposed in second position 92 on the downstream side of belt unit 31. Second position 92 is taking-in position of sample container 80 by smear preparation unit 20. Smear preparation unit 20 takes out sample container 80 transported to second position 92 and performs the smear preparation.
Transport unit 30 includes delivery unit 33a for pushing sample rack 81 from belt unit 31 to sample-rack collection unit 33. Sample-rack collection unit 33 moves delivery unit 33a in the Y direction, thereby moving sample rack 81 to sample-rack collection unit 33 side (the Y2 direction) and collecting sample rack 81 into sample-rack collection unit 33 from the other end portion (the X2-side end portion) of belt unit 31.
Transport unit 30 includes ID reading unit 35 for reading respective identification IDs of sample containers 80 held by sample rack 81 on belt unit 31. The identification ID is given to sample container 80 and sample rack 81 in a form such as a barcode or a two-dimensional code. ID reading unit 35 is a reader device for reading the identification ID. Transport unit 30 can transport sample rack 81 such that the sample is transported to a reading position where ID reading unit 35 reads the identification ID of sample container 80.
Transport unit 30 includes control unit 36 capable of communicating with information processing apparatus 40. Control unit 36 is configured by a control board or the like for controlling transport unit 30. Control unit 36 controls, according to a transporting operation command transmitted from information processing apparatus 40, delivery of sample rack 81 from sample-rack supply unit 32 onto belt unit 31, transport of sample container 80 to blood-cell-count measurement unit 10 and smear preparation unit 20, and delivery of sample rack 81 from belt unit 31 to sample-rack collection unit 33.
(Aspirator)
Aspirators (11 and 21) of blood-cell-count measurement unit 10 and smear preparation unit 20 are explained.
In the configuration example illustrated in
In the configuration example illustrated in
In the configuration example illustrated in
Gripping unit 11a grips sample container 80 held by sample rack 81 on first belt 31a and second belt 31b. Consequently, even in a configuration in which sample rack 81 can be transported in the forward and backward direction using belts (31a and 31b), transported sample container 80 can be gripped by gripping unit 11a. Therefore, it is possible to surely aspirate the sample. Gripping unit 11a grips, from the upward direction (the Z1-direction side), sample container 80 held by sample rack 81 on belt unit 31 and lifts sample container 80 upward to thereby take out sample container 80 from sample rack 81.
Container transfer unit 11b of aspirator 11 and aspirator 21 is configured as a holding unit that can hold sample container 80. Container transfer unit 11b can move to a position right above first position 91 or second position 92 of belt unit 31 and aspiration position 93 by aspiration tube 11c. Aspiration position 93 is provided on the inside of each of blood-cell-count measurement unit 10 and smear preparation unit 20 separated from the upward direction of belt unit 31. Container transfer unit 11b is disposed in a position further in the upward direction (the Z1-direction) than sample container 80 on sample rack 81. Sample container 80 taken out from sample rack 81 by gripping unit 11a is set in container transfer unit 11b.
When sample container 80 is returned to sample rack 81, container transfer unit 11b transfers sample container 80 from aspiration position 93 to a position right above first position 91 or second position 92. Gripping unit 11a grips and takes out sample container 80 from container transfer unit 11b. After container transfer unit 11b is retracted to a predetermined position on the inside, gripping unit 11a sets sample container 80 in sample rack 81 on belt unit 31.
With this configuration, immediately after sample container 80 is taken out from sample rack 81 by gripping unit 11a, transport unit 30 can start transport of sample rack 81.
(Smearing Unit)
Dripping unit 22a is connected to aspirator 21 in terms of fluid. Dripping unit 22a drips the sample having a dispensing amount A set under smearing conditions onto slide glass 85. Smearing member 22b is moved, by moving mechanisms 22c, in the up-down direction in which smearing member 22 approaches and separates from slide glass 85 and in a horizontal direction parallel to the surface of slide glass 85. Smearing unit 22 brings smearing member 22b close to the surface of slide glass 85 and translates smearing member 22b, thereby smearing the sample dripped onto the surface of slide glass 85. Smearing unit 22 can adjust, according to smearing conditions, the dispensing amount A of the sample, moving velocity V of smearing member 22b, and an inclination angle θ of smearing member 22b with respect to slide glass 85. The sample is smeared to be applied in an amount and thickness suitable for a microscopic test in which slide glass 85 is used.
Control unit 24 acquires, for each sample, information concerning the smearing conditions from information processing apparatus 40. Control unit 24 controls smearing unit 22 and staining unit 23 according to the smearing conditions set for each sample aspirated by aspirator 21.
(Information Processing Apparatus)
Information processing apparatus 40 is a computer including a CPU, a ROM, a RAM, a storage device such a hard disk, an input/output interface, a communication interface, and a reading device. The CPU executes computer program 60, whereby the computer functions as information processing apparatus 40. Information processing apparatus 40 includes display unit 42 and input device 43. Display unit 42 can display an analysis result and the like obtained by analyzing data of a digital signal transmitted from blood-cell-count measurement unit 10. Computer program 60 is, for example, read from a recording medium by the reading device and installed in information processing apparatus 40.
The CPU executes computer program 60, whereby information processing apparatus 40 functions as control unit 41 and transmits a transporting operation command to transport unit 30. In transport unit 30, control unit 36 (see
(Retest/Smear Preparation Rules)
When acquiring measurement data of the sample from blood-cell-count measurement unit 10, information processing apparatus 40 performs necessity determination of a retest and necessity determination of smear preparation according to retest/smear preparation rules 61.
Retest/specimen preparation rules 61 mainly include a repeat rule and a rerun/reflex rule concerning necessity determination of a retest, and a specimen preparation rule concerning necessity determination of smear preparation.
The repeat rule is a rule for determining, when a measurement error occurs, whether to execute a repeat test for performing a retest in the same measurement items as the measurement items of the initial test. The reflect rule and the rerun rule are rules for performing a retest, for example, when initial test measurement is normally performed but abnormality is present in measurement values. The reflex rule is a rule for determining whether to execute a reflex test for performing a retest concerning retest items including measurement items different from measurement items measured for the sample in the initial test. The rerun rule is a rule for determining whether to execute a rerun test for performing a retest in the same measurement items as the initial test.
The smear preparation rule is a rule for determining, based on a measurement result of the initial test or the retest of the sample, whether to prepare a smear sample of the sample.
As illustrated in
When acquiring the measurement order of the initial test, information processing apparatus 40 transmits the measurement order to blood-cell-count measurement unit 10 and causes blood-cell-count measurement unit 10 to carry out sample measurement of the initial test. When acquiring measurement data of the initial test from blood-cell-count measurement unit 10, information processing apparatus 40 transmits measurement result data to host apparatus 50, performs necessity determination of a retest according to retest/smear preparation rules 61. In a case where the retest is to be performed, information processing apparatus 40 sets a retest order including measurement items of the retest. The retest order is various because the retest order is set according to the measurement result of the initial test. For example, when it is determined that a retest is necessary for a measurement result of CBC (the number of all blood cells), a retest order to which a PLT is added to measurement items in addition to CBC is set.
Information processing apparatus 40 performs necessity determination of the smear preparation according to retest/smear preparation rules 61. In a case where the smear preparation is to be performed, information processing apparatus 40 sets a smear preparation order including smearing conditions. Note that, in a case where the retest and the smear preparation are not to be performed, a retest order and a smear preparation order are not set. The subsequent processing concerning the same sample is not performed.
When performing the retest, information processing apparatus 40 transmits the retest order to blood-cell-count measurement unit 10 and acquires measurement data of the retest from blood-cell-count measurement unit 10. When the smear preparation is performed, information processing apparatus 40 transmits the smear preparation order to smear preparation unit 20 and causes smear preparation unit 20 to execute the smear preparation. Information processing apparatus 40 transmits measurement result data to host apparatus 50 and performs determination by retest/smear preparation rules 61. To prevent the retest from being limitlessly repeated, the retest is limited to a predetermined number of times. Since the smear preparation is performed only once, when the smear preparation order is already set, the necessity determination of the smear preparation is not performed.
In this way, concerning the sample in respective sample containers 80, there are a large number of cases such as a case in which only the initial test is performed, a case in which the initial test and the retest are performed, a case in which the initial test and the smear preparation are performed, and a case in which the initial test, the retest, and the smear preparation are performed.
(Smearing Conditions)
Smearing condition list 62 includes smearing conditions. The smearing conditions includes, as parameter, the dispensing amount A (see
Information processing apparatus 40 designates, for each sample, smearing conditions in a smearing level corresponding to the determination conditions and transmits the smearing conditions to smear preparation unit 20. Consequently, smear preparation unit 20 is configured to prepare a smear under smearing conditions corresponding to a measurement result of the sample by blood-cell-count measurement unit 10. As a result, it is possible to prepare a high-quality smear under appropriate smearing conditions corresponding to a state of the sample grasped from the measurement result. Note that smear preparation unit 20 may always prepare a smear under the same smearing conditions. Rather than information processing apparatus 40, control unit 24 of smear preparation unit 20 may perform the determination of the smearing conditions.
In order to determine the smear conditions corresponding to the measurement result of the sample by blood-cell-count measurement unit 10, at least a measurement result of the initial test of the sample needs to be generated. The smear preparation order is set in advance before measurement of the sample in some case and set after the measurement of the sample based on the measurement result of the sample in other cases.
Therefore, as illustrated in
As illustrated in
In a condition in which the transport of sample container 80 to second position 92 is started before the generation of the measurement result, in order to set the smearing conditions, the measurement result only has to be acquired at the latest before timing when the sample is aspirated from sample container 80 in smear preparation unit 20 and smearing unit 22 starts the smearing processing. Note that, even in a condition in which the smear preparation order is set in advance before the measurement of the sample, control unit 41 may be configured to start the transport of sample container 80 to second position 82 after the generation of the measurement result of the sample.
(Transporting Operation Control of the Transport Unit)
Transporting operation control of transport unit 30 is explained in detail.
(Distribution of the Sample Containers on the Rack)
First, transport of each of the sample containers 80 held by sample rack 81 is explained. Control unit 41 causes transport unit 30 to sequentially transport sample containers 80 held by sample rack 81 to first position 91 and second position 92. In the following explanation, sample containers 80 held by sample rack 81 are referred to as first to eighth sample containers according to positions counted from the downstream side (the X2 side).
As illustrated in
For example, as illustrated in
By reciprocating sample rack 81 between blood-cell-count measurement unit 10 and smear preparation unit 20 in this way, even while any one sample container 80 is transported to blood-cell-count measurement unit 10 and the sample measurement is performed, it is possible to transport another sample container 80 to smear preparation unit 20 and start the smear preparation. As a result, it is possible to reduce the processing time required for the sample test processing including the sample measurement and the smear preparation.
In a configuration example illustrated in
That is, as illustrated in
Consequently, even after the other sample container 80 is transported to smear preparation unit 20, before the other sample container 80 is collected into sample rack 81, it is possible to collect one sample container 80 from blood-cell-count measurement unit 10 and transport the next sample container 80 to blood-cell-count measurement unit 10. As a result, during processing in one of blood-cell-count measurement unit 10 and smear preparation unit 20, it is possible to continuously carry out an operation for transporting sample container 80 to the other and causing the other to start processing. Therefore, it is possible to further reduce the processing time required for the sample test. When the sample measurement and the smear preparation are continued, control unit 41 can perform control to repeat the operation explained above.
(Transport Order of the Respective Sample Containers)
Transport order in transporting one sample container 80 to places is explained. For example, control unit 41 selects which of first position 91 and second position 92 sample container 80 for which the measurement of the initial test is already performed by blood-cell-count measurement unit 10 is to be first transported to. In this case, since the transport order is not fixed, for example, when both of the retest and the smear preparation are to be performed, it is possible to select blood-cell-count measurement unit 10 or smear preparation unit 20 to which sample container 80 can be transported more quickly, and then to transport sample container 80. As a result, it is possible to further reduce the processing time required for the sample test.
For example, concerning sample container 80 for which the measurement of the initial test by blood-cell-count measurement unit 10 is performed, control unit 41 causes transport unit 30 to transport sample container 80 to first position 91 or second position 92, to which a transport distance of sample rack 81 is shorter. Consequently, it is possible to reduce a time required for the transport of sample rack 81. Therefore, it is possible to reduce a standby time of blood-cell-count measurement unit 10 or smear preparation unit 20 to which sample container 80 is transported. As a result, it is possible to further reduce the processing time required for the sample test.
For example, in a condition in which both of a retest order and a smear preparation order are set for sample container 80 for which the measurement of the initial test is performed, control unit 41 causes transport unit 30 to transport sample container 80 in either one of (1) first transport of transporting sample container 80 first to first position 91 and then to second position 92 and (2) second transport of transporting sample container 80 first to second position 92 and then to first position 91.
Consequently, in a condition in which the same sample container 80 is to be transported to both of blood-cell-count measurement unit 10 and smear preparation unit 20, it is possible to transport sample container 80 to the positions in the order in which the standby time is short and sample container 80 can be more quickly processed. As a result, it is possible to further reduce the processing time required for the sample test.
As illustrated in
In this case, in the first transport, control unit 41 causes transport unit 30 to transport sixth sample container 80 to first position 91 at predetermined timing after the initial test and serves sixth sample container 80 for the sample measurement of the retest by blood-cell-count measurement unit 10. After the end of the retest, control unit 41 causes transport unit 30 to transport sixth sample container 80 to second position at predetermined timing and serves sixth sample container 80 for the smear preparation by smear preparation unit 20.
As illustrated in
Any of the first transport and the second transport can be selected depending on a transport distance of sample rack 81 and the operation states of blood-cell-count measurement unit 10 and smear preparation unit 20. For example, in a condition in which a transport distance of sample rack 81 to first position 91 is shorter than a transport distance of sample rack 81 to second position 92 and blood-cell-count measurement unit 10 is usable to measure the sample, control unit 41 selects the first transport.
Specifically, for example, as illustrated in
On the other hand, in a case where the transport distance of sample rack 81 to second position 92 is shorter than the transport distance of sample rack 81 to first position 91 and smear preparation unit 20 is usable to prepare a smear, control unit 41 selects the second transport. For example, as illustrated in
Note that the transport order of sample containers 80 is not limited to this. Control unit 41 may be configured to perform only either one of the first transport and the second transport. Control unit 41 may select a transport order without taking into account the transport distance of sample rack 81.
(Control Processing of the Blood Sample Testing Apparatus)
Control processing concerning rack transport of transport unit 30 in blood sample testing apparatus 100 is explained with reference to
(Transport Control Processing)
Examples of the unit transport processes include the measurement processing, the smear preparation processing, container return processing, rack taking-in processing, and ID reading processing. In this way, the unit transport processes include, besides the measurement processing and the smear preparation processing, the container return processing for executing an operation for collecting sample container 80 transported to blood-cell-count measurement unit 10 or smear preparation processing unit 20 from the transport destination of sample container 80.
In step S2, control unit 41 selects a unit transport process out of processing list 63 and executes the unit transport process. Control unit 41 selects and executes one unit transport process for processing executed once. Control unit 41 deletes the completed unit transport process from processing list 63.
In step S3, control unit 41 determines whether all the unit transport processes of processing list 63 end. That is, control unit 41 determines whether all the unit transport processes are deleted. In a case where a unit transport process remains in processing list 63, control unit 41 returns to step S1. In a case where all the unit transport processes are deleted, control unit 41 ends the processing.
In this way, in a processing example illustrated in
(Unit Transport Process)
All of the measurement processing, the smear preparation processing, and the container return processing are transporting operations each for moving a predetermined holding position of sample rack 81, in which sample container 80 is held, to a taking-in position of blood-cell-count measurement unit 10 or smear preparation processing 20 (i.e., first position 91 or second position 92) and supplying sample container 80 from sample rack 81 or collecting sample container 80 into sample rack 81.
When executing the measurement processing, the smear preparation processing, and the container return processing, in step S11, control unit 41 moves, with transport unit 30, predetermined sample container 80 or the predetermined holding position of sample rack 81 to the taking-in position of blood-cell-count measurement unit 10 or smear preparation unit 20. In step S12, control unit 41 stays on standby until sample container 80 is taken from sample rack 81 or until sample container 80 is returned to sample rack 81 in the transport destination.
The rack taking-in processing is processing for feeding sample rack 81 from sample-rack supply unit 32 to belt unit 31. When the rack taking-in processing is executed, in step S13, control unit 41 delivers sample rack 81 onto belt unit 31 with sample-rack supply unit 32. In step S14, control unit 41 adds ID reading processing for sample container 80 held by sample rack 81 to processing list 63.
The ID reading processing is processing for transporting sample container 80 held by sample rack 81 to ID reading positions of ID reading unit 35. Eight ID reading positions are set to correspond to respective eight holding positions of sample rack 81. When executing the ID reading processing, in step S15, control unit 41 causes transport unit 30 to transport sample rack 81 to the ID reading positions. In step S16, information processing apparatus 40 inquires host apparatus 50 about a measurement order and a smear preparation order using a sample ID of sample container 80 read by ID reading unit 35. In step S17, control unit 41 adds measurement processing and smear preparation processing corresponding to the measurement order and the smear preparation order acquired from host apparatus 50 to processing list 63.
<Processing List Update Processing>
In step S21, control unit 41 determines whether new sample rack 81 is present in sample-rack supply unit 32. In a case where new sample rack 81 is absent, control unit 41 advances the processing to step S23. In a case where new sample rack 81 is present, in step S22, control unit 41 adds rack taking-in processing to processing list 63.
In step S23, control unit 41 acquires a measurement result by blood-cell-count measurement unit 10.
In step S24, control unit 41 determines, based on the acquired measurement result and retest/smear preparation rules 61 (see
In a case where a retest order is to be set, in step S25, control unit 41 sets the retest order in association with the sample ID and adds measurement processing to processing list 63. In a case where a retest order is not to be set in step S24, control unit 41 advances the processing to step S26.
In step S26, control unit 41 determines, based on the acquired measurement result and retest/smear preparation rules 61 (see
In a case where a smear preparation order is to be set, in step S27, control unit 41 sets a smear preparation order in association with the sample ID and adds smear preparation processing to processing list 63. In a case where a smear preparation order is not set in step S26, control unit 41 advances the processing to step S28.
In step S28, control unit 41 determines, concerning measured all measurement results, whether the determination for determining whether the retest and the smear preparation is performed ends. In a case where the determination does not end, control unit 41 acquires the next measurement result in step S23 and performs necessity processing based on retest/smear preparation rules 61. In a case where the determination concerning the measured all measurement results ends, control unit 41 advances the processing to step S29.
In step S29, control unit 41 determines whether an aspiration completion notification is received from blood-cell-count measurement unit 10 or from smear preparation unit 20. In a case where the aspiration completion notification is received, control unit 41 adds container return processing to processing list 63 in step S30. In a case where the aspiration completion notification is not received, control unit 41 advances the processing to step S31.
In step S31, control unit 41 determines, concerning sample rack 81 on belt unit 31, whether sample rack 81 for which all the unit transport processes such as the measurement processing, the smear preparation processing, and the container return processing are completed is present. In a case where sample rack 81 for which all the unit transport processes are completed is present, in step S32, control unit 41 adds rack discharge processing to processing list 63 and ends the processing list update processing. The rack discharge processing is processing for transporting sample rack 81 to sample-rack collection unit 33 with delivery unit 33a. In a case where sample rack 81 for which all the unit transport processes is completed is absent, control unit 41 ends the processing list update processing without adding the rack discharge processing.
(Selection and Execution Processing of the Unit Transport Process)
In step S41, control unit 41 determines selection order of the unit transport processes to be executed. In this example, control unit 41 determines the selection order of the unit transport processes depending on the present position of sample rack 81 at selection and execution timing of each unit transport process.
Specifically, control unit 41 causes transport unit 30 to transport rack 81 preferentially to blood-cell-count measurement unit 10 or smear preparation unit 20 to which a distance from sample rack 81 is shorter. That is, first, control unit 41 determines whether to execute a unit transport process for blood-cell-count measurement unit 10 or smear preparation unit 20 which is closer from the present position of sample rack 81 and has a shorter transport distance of sample rack 81. In a case where the unit transport process for blood-cell-count measurement unit 10 or smear preparation unit 20 which has the shorter transport distance is absent, control unit 41 determines whether to execute the unit transport process for blood-cell-count measurement unit 10 or smear preparation unit 20 to which the transport distance is longer. In a case where the transport distance of sample rack 81 to blood-cell-count measurement unit 10 is shorter, control unit 41 advances the processing to step S42 first and determines blood-cell-count measurement unit 10 first. In a case where the transport distance of sample rack 81 to smear preparation unit 20 is shorter, control unit 41 advances processing to step S46 first and determines smear preparation unit 20 first.
In step S42, control unit 41 determines whether the container return processing of blood-cell-count measurement unit 10 is present in processing list 63. In a case where the container return processing is absent, control unit 41 advances the processing to step S44. In a case where the container return processing is present, in step S43, control unit 41 executes the container return processing and, after the execution, advances the processing to step S57.
In step S44, control unit 41 determines whether the following conditions (1) to (3) are satisfied. (1) The transport distance of sample rack 81 from the present position to blood-cell-count measurement unit 10 is shorter than the transport distance of sample rack 81 from the present position to smear preparation unit 20, (2) the measurement processing is present in processing list 63, and (3) blood-cell-count measurement unit 10 is usable to measure the next sample.
In a case where the conditions (1) to (3) are not satisfied, control unit 41 advances the processing to step S50. In a case where the conditions (1) to (3) are satisfied, control unit 41 executes the measurement processing in step S45 and, after the execution, advances the processing to step S57.
On the other hand, in step S46, control unit 41 determines whether the container return processing of smear preparation unit 20 is present in processing list 63. In a case where the container return processing is absent, control unit 41 advances the processing to step S48. In a case where the container return processing is present, in step S47, control unit 41 executes the container return processing and, after the execution, advances the processing to step S57.
In step S48, control unit 41 determines whether the following conditions (4) to (6) are satisfied. (4) The transport distance of sample rack 81 from the present position to smear preparation unit 20 is shorter than the transport distance of sample rack 81 from the present position to blood-cell-count measurement unit 10, (5) the smear preparation processing is present in processing list 63, and (6) smear preparation unit 20 is usable to perform the smear preparation of the next sample.
In a case where the conditions (4) to (6) are not satisfied, control unit 41 advances the processing to step S50. In a case where the conditions (4) to (6) are satisfied, control unit 41 executes the smear preparation processing in step S49 and, after the execution, advances the processing to step S57.
In step S50, control unit 41 determines whether the determination is completed for both of blood-cell-count measurement unit 10 or smear preparation unit 20, the transport distance of sample rack 81 to which from the present position is shorter, and blood-cell-count measurement unit 10 or smear preparation unit 20, the transport distance of sample rack 81 to which from the present position is longer. In a case where the determination is performed for only blood-cell-count measurement unit 10 or smear preparation unit 20, the transport distance of sample rack 81 to which is shorter, control unit 41 returns the processing to step S41 and executes the processing concerning blood-cell-count measurement unit 10 or smear preparation unit 20, the transport distance of sample rack 81 to which is longer. That is, in a case where the transport distance of sample rack 81 to blood-cell-count measurement unit 10 is shorter, control unit 41 advances the processing from step S41 to step S46. In a case where the transport distance of sample rack 81 to smear preparation unit 20 is shorter, control unit 41 advances the processing from step S41 to step S42.
In a case where the determination is completed for both of blood-cell-count measurement unit 10 and smear preparation unit 20, in step S51, control unit 41 determines whether the ID reading processing is present in processing list 63. In a case where the ID reading processing is present, in step S52, control unit 41 executes the ID reading processing.
In a case where the ID reading processing is absent, in step S54, control unit 41 determines whether the rack taking-in processing is present in processing list 63. In a case where the rack taking-in processing is present, in step S54, control unit 41 executes the rack taking-in processing.
In a case where the rack taking-in processing is absent, in step S55, control unit 41 determines whether the rack discharge processing is present in processing list 63. In a case where the rack discharge processing is present, control unit 41 executes the rack discharge processing in step S56.
In a case where the rack discharge processing is absent, control unit 41 ends the selection and execution processing of the unit transport processes and advances the processing to step S3 in
In the processing example illustrated in
Further, in the processing example illustrated in
In the processing example illustrated in
(Operation Example of the Blood Sample Testing Apparatus)
An example of the operation of blood sample testing apparatus 100 is explained with reference to
In
When sample rack 81 is fed into belt unit 31 at time t1, a sample ID of first sample container 80 is read at time t2. First sample container 80 is transported to first position 91 at time t3 and measurement of the first sample by blood-cell-count measurement unit 10 is started. At time t8, a first holding position of sample rack 81 is moved to first position 91, and first sample container 80 is returned from blood-cell-count measurement unit 10.
Second sample container 80 is transported to blood-cell-count measurement unit 10 at time t9 and returned from blood-cell-count measurement unit 10 at time t14. Third sample container 80 is transported to blood-cell-count measurement unit 10 at time t15 and returned from blood-cell-count measurement unit 10 at time t20.
In this operation example, the retest of third sample container 80 is performed next. Returned third sample container 80 is transported to blood-cell-count measurement unit 10 again at time t21 and returned from blood-cell-count measurement unit 10 at time t26. Fourth sample container 80 is transported to blood-cell-count measurement unit 10 at time t27 and returned from blood-cell-count measurement unit 10 at time t32.
Fifth sample container 80 is transported to blood-cell-count measurement unit 10 at time t33 and returned from blood-cell-count measurement unit 10 at time t38. Between time t33 and time 38, immediately after fifth sample container 80 is transported to blood-cell-count measurement unit 10 at time t33, movement of sample rack 81 to smear preparation unit 20 side is started at time t34, and fourth sample container 80 is transported to smear preparation unit 20 at time t35. Movement of sample rack 81 to blood-cell-count measurement unit 10 side is started at time t37, and sample rack 81 is returned to blood-cell-count measurement unit 10 side. This is equivalent to the transporting operation illustrated in
Fourth sample container 80 is returned from smear preparation unit 20 to sample rack 81 at time t44. Sixth sample container 80 is transported to blood-cell-count measurement unit 10 at time t39 and returned from blood-cell-count measurement unit 10 at time t44. Sixth sample container 80 is transported to smear preparation unit 20 at time t45. Seventh sample container 80 is transported to blood-cell-count measurement unit 10 at time t47 and returned from blood-cell-count measurement unit 10 at time t52.
Eighth sample container 80 is transported to blood-cell-count measurement unit 10 at time t53 and returned from blood-cell-count measurement unit 10 at time t58. Between time t53 and time t58, movement of sample rack 81 to smear preparation unit 20 side is started at time t55. Sixth sample container 80 is returned from smear preparation unit 20 to sample rack 81 at time t56. Movement of sample rack 81 to blood-cell-count measurement unit 10 side is started at time t57, and sample rack 81 is returned to blood-cell-count measurement unit 10 side. This is equivalent to the transporting operation illustrated in
Thereafter, the retest of sixth sample container 80 is performed. Sixth sample container 80 is transported to blood-cell-count measurement unit 10 again at time t59 and returned from blood-cell-count measurement unit 10 at time t64. In this example, in the operation example illustrated in
Consequently, the measurement and the smear preparation of all of sample containers 80 held by sample rack 81 are completed. Therefore, sample rack 81 is discharged from belt unit 31 to sample-rack collection unit 33 at time t65.
Note that, although not illustrated in the figure, in a case where sample rack 81 is transported to smear preparation unit 20 and the smear preparation is performed after all the kinds of sample measurement including the initial test and the retest are ended, sample rack 81 is discharged to sample-rack collection unit 33 at time t87. Therefore, as illustrated in
In this case, in order to shift timing for collecting fourth sample container 80 from smear preparation unit 20, measurement of fifth sample container 80 started at time t36. Therefore, the initial test of sixth sample container 80 is delayed and ends at time t47. Returned sixth sample container 80 is transported to blood-cell-count measurement unit 10 again at time t48 and returned to sample rack 81 at time t53. Thereafter, sixth sample container 80 is transported to smear preparation unit 20 at time t55 and returned to sample rack 81 at time t68. The measurement and the smear preparation of all of sample containers 80 are completed and sample containers 80 are discharged to sample rack 81 at time t71.
Therefore, in this operation example, since the first transport illustrated in
According to the above explanation, since sample containers 80 for which the retest order and the smear preparation order are set and sample container 80 for which the retest order and the smear preparation order are not set are mixed, the transporting operation of sample rack 81 is complicated. As in one or more embodiments, it is seen that the processing time required for the sample test is effectively reduced by the control for selecting the first transport and the second transport and preferentially transporting sample rack 81 to blood-cell-count measurement unit 10 or smear preparation unit 20, to which the transport distance of sample rack 81 is shorter.
Note that it should be considered that the embodiment disclosed herein is illustrative in all aspects and is not limiting. The scope of the present invention is indicated by claims rather than the above explanation of the embodiment. Further, all changes within meanings and scopes equivalent to the claims are included in the scope of the present invention.
Number | Date | Country | Kind |
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2016-191450 | Sep 2016 | JP | national |