The present invention relates to a biosafety cabinet that eliminates, using an air barrier, a contamination risk from outside.
In the related art, in the industrial fields such as the medical field and the pharmaceutical field, a biosafety cabinet is used as a countermeasure against biological hazard. The biosafety cabinet has the isolation capability of being able to protect a specimen from sundry bacteria from outside by providing an air barrier and performing an operation in a partitioned space having an opening portion in a portion thereof.
Patent Document 1 and Patent Document 2 disclose the background art of the technical field. Patent Document 1 discloses a biosafety cabinet that includes a coupling portion connected to an exhaust port of the biosafety cabinet, an opening portion which is different from the coupling portion and into which air flows, and an open type duct having an exhaust duct, the cabinet includes a differential pressure sensor that detects a difference between a pressure in a space where the open type duct is disposed and a pressure in the open type duct, and detection means for outputting a detection signal when an absolute value of the differential pressure sensor becomes less than or equal to a predetermined threshold value. In addition, Patent Document 2 discloses a point that see-through windows are provided in a portion of a back wall or a side wall of an operation space of the biosafety cabinet and in a portion of a main body rear wall or a main body side wall of a biosafety cabinet which is separated from the back wall or the side wall by a circulation flow path, so as to enable an operator to see through both walls, a display device is installed in an outside part of the see-through window, and the operator inserts the arms from a front opening portion of the biosafety cabinet to perform an operation from a front shutter while seeing the operation space.
Patent Document 1: JP 2017-078527 A
Patent Document 2: JP 2016-165249 A
As shown in Patent Document 1 and Patent Document 2, in the biosafety cabinet for safely performing an operation while maintaining an inside purity, there is a case where the operator uses a bottle containing a solution such as purified water, a pharmaceutical solution, or a reagent in the biosafety cabinet. At the time, if the bottle is disposed on an operation stage in the operation space, the operation stage becomes contaminated, which is a concern. Furthermore, an air flow becomes restricted, which is a concern. In addition, the operation space above the operation stage is reduced, which is a problem. For this reason, it is conceivable to hold the bottle in the air via a bottle holder; however, at the time, a bottle holder which is capable of facilitating the exchange of the bottle has not been considered.
The present invention is made in light of the problems, and an object of the present invention is to provide a bottle holder that is capable of facilitating the exchange of a bottle, and a biosafety cabinet having a bottle holder.
The present invention is made in light of the background art and the problems, and as an example of the present invention, there is provided a bottle holder for a bottle that is used in a biosafety cabinet which has an operation space and is provided with a support rod lying across the operation space in a width direction, the holder including: a side holding portion that holds a side periphery of the bottle; a bottom holding portion that holds the vicinity of a bottle cap of the bottle and has a bottom opening which embraces the bottle cap; and an opening, which continues from the bottom opening to an upper surface, in the bottom holding portion and the side holding portion, in which the holder holds the bottle downward.
According to the present invention, it is possible to provide a bottle holder that is capable of facilitating the exchange of a bottle, and a biosafety cabinet having a bottle holder.
Hereinafter, examples of the present invention will be described with reference to the drawings.
First of all, initially, a biosafety cabinet in the related art which is the premise of the present example will be described.
An opening is provided in a central area of a housing 101 of a biosafety cabinet 100, and an operation space 104 is provided therebehind. A front plate 102 is provided on a front surface side of the operation space 104 so as to block an upper portion of the opening, an operation opening 103 is provided on a lower side thereof, and an operator inserts the hands into the operation space 104 from the operation opening 103 to perform an operation. The front plate 102 is formed of a transparent material such as glass, and the operator can see an operation through the front plate. In addition, a support rod 20 lies across the operation space 104 in a width direction, and a specimen, an instrument, or the like including an infusion solution bag which is used in the operation space can be suspended thereon.
An operation stage 105 which is substantially planar is provided on a bottom surface of the operation space 104, and the operator performs an operation on the operation stage. An air intake port 107 leading downward is provided close to the operation opening 103 on a front side of the operation stage 105. The air intake port 107 is formed of, for example, a slit that extends along the operation opening 103 in a rightward and leftward direction of the housing. A back flow path 108 leading from the air intake port 107 to an upper portion of the housing is provided on a back surface side of the operation space 104.
An air blow side fan filter unit (FFU) 109 is provided above the operation space 104. The air blow side FFU 109 is formed of a fan which is rotated by a motor, and a filter, for example, a HEPA filter 109A which removes microparticles, and blows purified air, from which the microparticles are removed, into the operation space 104. An exhaust side fan filter unit (FFU) 110 is provided in the upper portion of the housing 101, and removes microparticles from a portion of air with a filter, for example, a HEPA filter 110A to exhaust the portion of air outside the device.
In
Therefore, even though the operator inserts the hands into the operation space 104 through the operation opening 103 to perform an operation, it is possible to realize the maintenance of the purity and the prevention of contamination.
Here, there is a case where the operator uses a bottle containing a solution such as purified water, a pharmaceutical solution, or a reagent in the biosafety cabinet. At the time, if the bottle is disposed on the operation stage in the operation space, the operation stage becomes contaminated, which is a concern. Furthermore, an air flow becomes restricted, which is a concern. In addition, the operation space above the operation stage becomes small, which is a problem. Then, it is conceivable to suspend, via a bottle holder, the bottle on the support rod on which a specimen, an instrument, or the like including an infusion solution bag which is used in the operation space can be suspended and which lies across the operation space in the width direction; however, merely if the bottle is suspended, the solution does not naturally come out from the bottle, which a problem. Then, it is configured that a tube is attached to the bottle, the bottle is held in the air with the tube facing downward, a cock is provided in the middle of the tube, and the solution in the bottle can be injected into the specimen by opening the cock when necessary.
In the present example, hereinafter, a bottle holder which is capable of facilitating the exchange of the bottle with a tube will be described.
As illustrated in
As described above, the bottle holder in the present example has the opening 45 that continues from the bottom opening 46 to the upper surface in the bottom holding portion 42 and the front holding portion 41. Therefore, even though there is a tube, it is possible to easily exchange the bottle. When exchanging the bottle with a tube, it is possible to realize a simple operation of temporarily stopping the solution from flowing with the cock provided in the middle of the tube, replacing only the bottle, and continuing to reuse the bottle with a tube. In addition, the opening 45 also provides the effect of being able to easily read the label 33 which discloses the contents of the bottle.
Incidentally, in
As described above, according to the present example, it is possible to provide the bottle holder that is capable of facilitating the exchange of the bottle with a tube.
In the present example, a configuration where a bottle holder is provided with a hook portion onto which a hook for suspending on the support rod is to be hung will be described.
As described above, according to the present example, it is possible to provide the bottle holder that is capable of facilitating the exchange of the bottle with a tube, and a biosafety cabinet having the bottle holder.
In the present example, a bottle holder for a bottle which is taper-shaped on a bottle cap side will be described.
As described above, according to the present example, it is possible to provide the bottle holder that is capable of reliably holding also the bottle with a taper.
In the present example, a configuration where a bottle holder is provided with a temperature regulation mechanism will be described.
If there is a temperature difference between a specimen and a solution in the bottle, when the solution in the bottle is injected into the specimen, there is a possibility of causing a temperature difference in the specimen and generating a temperature history in the cultured cells or the like. In order to prevent the possibility, in the present example, a bottle holder is provided with a temperature regulation mechanism. In particular, since in many cases, it is desirable to raise the temperature higher than a room temperature when performing an operation in the biosafety cabinet, a heating mechanism is provided as the temperature regulation mechanism. Various means such as a nichrome wire heater and a ceramic heater can be applied as the heating mechanism. A configuration view in the present example is not illustrated; however, it is possible to heat the bottle holder and to heat the solution in the bottle held with the bottle holder by adding the heating mechanism at a random location on the bottle holder. Incidentally, the bottle holder is preferably made of stainless steel due to the ease to raise the temperature and the ease to maintain a purified state. In addition, the bottle held with the bottle holder may be directly heated instead of heating the bottle holder.
In addition, since it is necessary to supply an electric power to the heating mechanism, it is possible to realize an electric power supply to the heating mechanism of the bottle holder via the support rod 20, for example, by providing an electric power supply wiring integrally with the hook 48 in
As described above, according to the present example, it is possible to provide the bottle holder which when a solution in the bottle is injected into a specimen, is capable of preventing the generation of a temperature history induced by a temperature difference in the specimen.
In the present example, a specific configuration of the bottle holder in Example 3 will be described.
In
In addition, the bottle holder has a structure where the hook portion 47 is provided in each of the right side holding portion 44R and the left side holding portion 44L, and the bottle can be suspended on the support rod via the hook 48 coupled to the support rod by hanging the U-shaped part of the hook 48, which is an accessory to the support rod, onto the hook portion 47. Incidentally, the hook 48 is detachable by inserting and removing the hook portion 47 in an opening direction of the U-shaped part of the hook 48.
As described above, according to the present example, it is possible to provide the bottle holder that is capable of facilitating the exchange of the bottle with a tube, and a biosafety cabinet having the bottle holder.
In the present example, a specific configuration of a bottle holder, which corresponds to a bottle where the bottle cap is formed to be inclined rather than facing directly upward, will be described.
In
As described above, according to the present example, it is possible to provide the bottle holder that is capable of reliably holding the bottle where the bottle cap is formed to be inclined and facilitating the exchange of the bottle with a tube, and a biosafety cabinet having the bottle holder.
The examples have been described above; however, the present invention is not limited to the examples, and includes various modification examples. For example, the examples have been described in detail so as to facilitate the understanding of the present invention, and the present invention is not necessarily limited to including all of the described configurations. In addition, a portion of a configuration of an example can be replaced with a configuration of another example. In addition, a configuration of another example can also be added to a configuration of an example. In addition, the addition, the deletion, or the replacement of another configuration can be made with respect to a portion of a configuration of each example.
20 Support rod
30 Bottle main body
31 Bottle cap
32 Tube
33 Label
34 Taper portion
41 Front holding portion
42 Bottom holding portion
43 Rear holding portion
44R Right side holding portion
44L Left side holding portion
45 Opening
46 Bottom opening
47 Hook portion
48 Hook
100 Biosafety cabinet
101 Housing
102 Front plate
103 Operation opening
104 Operation space
105, 105T Operation stage
107 Air intake port
108 Back flow path
109 Air blow side fan filter unit (FFU)
109A Air blow side HEPA filter
110 Exhaust side fan filter unit (FFU)
110A Exhaust side HEPA filter
Number | Date | Country | Kind |
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2018-083424 | Apr 2018 | JP | national |
Filing Document | Filing Date | Country | Kind |
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PCT/JP2019/003894 | 2/4/2019 | WO | 00 |