E. K. Rowinsky and R.C. Donehower, "The Clinical Pharmacology and Use of Antimicrotubule Agents in Cancer Chemotherapeutics," Pharmac. Ther., 52:35-84, 1991. |
C. M. Spencer and D. Faulds, "Paclitaxel, A Review of its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Potential in the Treatment of Cancer," DRUGS, 48(5), 794-847, 1994. |
K.C. Nicolaou, et al, "Chemistry and Biology of Taxol," Angew. Chem., Int. Ed. Engl., 33:15-44, 1994. |
Greene and Wuts, Protective Groups in Organic Synthesis, 2nd Ed., John Wiley & Sons, and McOmie, 1991. |
Protective Groups in Organic Chemistry, Ed. J.F.W. McOmie, Plenum Press, 1973. |
S.-H. Chen, et al, "First Syntheses of Novel Paclitaxel (Taxol) Analogs Modified at the C4-Position," J. Org. Chem., 59, pp. 6156-6158, 1994. |
S.-H. Chen, et al, "Structure-Activity Relationships of Taxol: Synthesis and Biological Evaluation of C2 Taxol Analogs," Bioorganic and Medicinal Chemistry Letters, vol. 4, No. 3, pp. 479-482, 1994. |
R.A. Johnson, et al, "Taxol Chemistry. 7-O-Triflates as Precursors to Olefins and Cyclopropanes," Tetrahedron Letters, vol. 35, No. 43, pp. 7893-7896, 1994. |
G. Roth, et al, "Reaction of Paclitaxel and 10-Desacetyl Baccatin III with Diethylamino Sulfurtrifluoride," Tetrahedron Letters, vol. 36, No. 10, pp. 1609-1612, 1995. |
S.-H. Chen, et al, "The Chemistry of Taxanes: Reaction of Taxol and Baccatin Derivatives with Lewis Acids in Aprotic and Protic Media," Tetrahedron, vol. 49, No. 14, pp. 2805-2828, 1993. |
Physician's Desk Reference, 49th Edition, Medical Economics, p. 682, 1995. |
J. Kant, et al, "A Chemoselective Approach to Functionalize the C-10 Position of 10-Deacetylbaccatin III. Synthesis and Biological Properties of Novel C-10 Taxel Analogues," Tetrahedron Letters, 35, No. 31, pp. 5543-5546, 1994. |
S.-H. Chen, et al, "Taxol.RTM. Structure-Activity Relationships: Synthesis and Biological Evaluation of Taxol Analogs Modified at C-7," Bioorganic & Medicinal Chemistry Letters, vol. 4, No. 18, pp. 2223-2228, 1994. |
Mahendra D. Chordia, et al, "Synthesis and Biological Evaluation of 4-Deacetoxy-paclitaxel," Tetrahedron Letters, vol. 35, No. 37, pp. 6843-6846, 1994. |
D. A. Scudieri, et al, Evaluation of Soluble Tetrazolium/ Formazan Assay for Cell Growth and Drug Sensitivity in Culture Using Human and Other Tumor Cell Lines, Cancer Res., vol. 48, pp. 4827-4833. 1988. |
K.A. Neidigh, et al, "Synthesis and Biological Evaluation of 4-Deacetylpaclitaxel," Tetrahedron Letters, vol. 35, No. 37, pp. 6839-6842, 1994. |