Claims
- 1. A compound having the formula ##STR16## wherein R.sup.1 is a tricycloalkyl or bicycloalkyl group having from 7 to 11 carbon atoms, or indan-2-yl;
- R.sup.2 is methyl or ethyl;
- X is O or NH; and
- Y is ##STR17## a pharmaceutically acceptable acid addition salt of said compound having a basic nitrogen atom; or the racemicdiastereomeric mixtures and optical isomers of said compounds.
- 2. A compound according to claim 1 wherein X is O and Y is ##STR18##
- 3. A compound according to claim 2 wherein R.sup.1 is bicycloalkyl.
- 4. The compound according to claim 3 wherein R.sup.1 is bicyclo[2.2.1]hept-2-yl; R.sup.2 is methyl; and Y is ##STR19##
- 5. The compound according to claim 3 wherein R.sup.1 is indan-2-yl; and R.sup.2 is methyl; and Y is ##STR20##
- 6. A compound according to claim 1 wherein X is O and Y is ##STR21##
- 7. A compound according to claim 6 wherein R.sup.1 is bicycloalkyl.
- 8. The compound according to claim 7 wherein R.sup.1 is bicyclo[2.2.1]-hept-2-yl; R.sup.2 is methyl; and Y is ##STR22##
- 9. The compound according to claim 7 wherein R.sup.1 is indan-2-yl; R.sup.2 is methyl; and Y is ##STR23##
- 10. A method for treating depression in a human suffering therefrom which comprises administering to said human an effective anti-depression treating amount of a compound according to claim 1.
- 11. A method according to claim 10 wherein said compound has the formula ##STR24## wherein R.sup.1 is a bicycloalkyl group and Y is selected from the group consisting of ##STR25##
- 12. A method according to claim 11 wherein R.sup.1 is bicyclo[2.2.1]hept-2-yl or indanyl and R.sup.2 is methyl.
- 13. The method according to claim 12 wherein R.sup.1 is bicyclo[2.2.1]hept-2yl; and Y is ##STR26##
- 14. A pharmaceutical composition for treating depression in a human suffering therefrom which comprises an effective anti-depression treating amount of a compound according to claim 1 and a pharmaceutically acceptable carrier.
Parent Case Info
This is a division of co-pending application Ser. No. 07/696,690, filed on May 30, 1991 now U.S. Pat. No. 5,128,358, which is a division of application Ser. No. 07/155,932, filed Jan. 19, 1988, now allowed as a request for U.S. examination of International application PCT/US/00958, filed Apr. 29, 1986.
US Referenced Citations (11)
Divisions (2)
|
Number |
Date |
Country |
Parent |
696690 |
Aug 1991 |
|
Parent |
155932 |
Jan 1988 |
|