Claims
- 1 (NEW). An isolated polypeptide encoded by a nucleic acid molecule comprising a nucleotide sequence selected from the group consisting of:
(a) SEQ ID NO: 3; (b) nucleotides 243 through 1307 of SEQ ID NO: 3; and (c) a nucleotide sequence encoding an amino acid sequence selected from the group consisting of SEQ ID NO: 10, the amino acid sequence of SEQ ID NO: 10 from which one through five amino acids have been removed from the N-terminus, the amino acid sequence of SEQ ID NO: 10 from which one through five amino acids have been removed from the C-terminus, amino acids 23 through 279 of SEQ ID NO: 10, the amino acid sequence of a kinase domain that is at least 90% identical to amino acids 23 through 279 of SEQ ID NO: 10; and the amino acid sequence of a kinase domain that is at least 95% identical to amino acids 23 through 279 of SEQ ID NO: 10.
- 2 (NEW). The polypeptide of claim 1 in non-glycosylated form.
- 3 (NEW). The polypeptide of claim 1 encoded by a nucleic acid molecule comprising nucleotides 243 through 1307 of SEQ ID NO: 3.
- 4 (NEW). The polypeptide of claim 1 encoded by a nucleic acid molecule comprising a nucleotide sequence encoding amino acids 23 through 279 of SEQ ID NO: 10.
- 5 (NEW). The polypeptide of claim 1 encoded by a nucleic acid molecule comprising a nucleotide sequence encoding a kinase domain that is at least 95% identical to amino acids 23 through 279 of SEQ ID NO: 10.
- 6 (NEW). An isolated polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 10, the amino acid sequence of SEQ ID NO: 10 from which one through five amino acids have been removed from the N-terminus, the amino acid sequence of SEQ ID NO: 10 from which one through five amino acids have been removed from the C-terminus, amino acids 23 through 279 of SEQ ID NO: 10, the amino acid sequence of a kinase domain that is at least 90% identical to amino acids 23 through 279 of SEQ ID NO: 10, and the amino acid sequence of a kinase domain that is at least 95% identical to amino acids 23 through 279 of SEQ ID NO: 10.
- 7 (NEW). The polypeptide of claim 6 in non-glycosylated form.
- 8 (NEW). The polypeptide of claim 6 comprising SEQ ID NO: 10.
- 9 (NEW). The polypeptide of claim 6 comprising amino acids 23 through 279 of SEQ ID NO: 10.
- 10 (NEW). The polypeptide of claim 6 comprising the amino acid sequence of a kinase domain that is at least 95% identical to amino acids 23 through 279 of SEQ ID NO: 10.
- 11 (NEW). An isolated polypeptide produced according to the method of culturing a recombinant host cell comprising a nucleic acid encoding said polypeptide under conditions promoting expression of said polypeptide, wherein said polypeptide comprises an amino acid sequence selected from the group consisting of SEQ ID NO: 10, the amino acid sequence of SEQ ID NO: 10 from which one through five amino acids have been removed from the N-terminus, the amino acid sequence of SEQ ID NO: 10 from which one through five amino acids have been removed from the C-terminus, amino acids 23 through 279 of SEQ ID NO: 10, the amino acid sequence of a kinase domain that is at least 90% identical to amino acids 23 through 279 of SEQ ID NO: 10, and the amino acid sequence of a kinase domain that is at least 95% identical to amino acids 23 through 279 of SEQ ID NO: 10.
- 12 (NEW). The polypeptide produced according to the method of claim 11, wherein the nucleic acid comprises a nucleotide sequence selected from the group consisting of:
(a) SEQ ID NO: 3; (b) nucleotides 243 through 1307 of SEQ ID NO: 3; and (c) a nucleotide sequence encoding an amino acid sequence selected from the group consisting of SEQ ID NO: 10, the amino acid sequence of SEQ ID NO: 10 from which one through five amino acids have been removed from the N-terminus, the amino acid sequence of SEQ ID NO: 10 from which one through five amino acids have been removed from the C-terminus, amino acids 23 through 279 of SEQ ID NO: 10, and the amino acid sequence of a kinase domain that is at least 95% identical to amino acids 23 through 279 of SEQ ID NO: 10.
- 13 (NEW). The polypeptide produced according to the method of claim 11, wherein the recombinant host cell is selected from the group consisting of bacterial cells, yeast cells, plant cells, insect cells, and animal cells.
- 14 (NEW). The polypeptide produced according to the method of claim 11 in non-glycosylated form.
- 15 (NEW). The polypeptide produced according to the method of claim 11, wherein the polypeptide comprises SEQ ID NO: 10.
- 16 (NEW). The polypeptide produced according to the method of claim 11, wherein the polypeptide comprises amino acids 23 through 279 of SEQ ID NO: 10.
- 17 (NEW). The polypeptide produced according to the method of claim 11, wherein the polypeptide comprises the amino acid sequence of a kinase domain that is at least 95% identical to amino acids 23 through 279 of SEQ ID NO: 10.
Parent Case Info
[0001] This application is a divisional application of U.S. Ser. No. 09/579,664, filed May 26, 2000; which claims the priority under 35 U.S.C. § 119(e) of provisional application U.S. Serial No. 60/136,781, filed May 28, 1999, all of which are incorporated by reference herein.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60136781 |
May 1999 |
US |
Divisions (1)
|
Number |
Date |
Country |
Parent |
09579664 |
May 2000 |
US |
Child |
10355975 |
Jan 2003 |
US |