Not Applicable
Not Applicable
Not Applicable
The transmission of ultrasound pulses is actually the energy traveling of acoustic pulses in the medium. Currently, it is supposed that the speed of ultrasound pulses is fixed in the same medium during transmission. Actually, the energy of ultrasound pulses is gradually reduced due to the acoustic impedance of transmitting medium. The acoustic impedance is directly related to the speed of ultrasound pulses in the medium. So, the question is if the speed of ultrasound pulses can still keep the same when its energy is gradually lower until exhausted?
Ultrasound pulses can be reflected by motionless or moving objects, and it is considered that forward moving objects can compress ultrasound frequency and reversely moving objects decompress the ultrasound frequency. So, Doppler has been widely used to measure the velocity of moving objects based on frequency shift, such as medical ultrasound machine and Doppler radar. In pulse wave Doppler, aliasing is explained with insufficient Doppler sampling rate of the frequency domain analysis. But, the theory of frequency domain can not completely solve the aliasing problem in pulse Doppler and color Doppler.
Comparing lower frequency ultrasound, higher frequency ultrasound has larger attenuation coefficient and thus is more readily absorbed in medium, which limits the depth of penetration. So, if there is way to increase the penetration of higher frequency ultrasound?
Emitted from activated PZT, ultrasound pulses contain their quantity and size. Unlike the changes of sounds from coming or leaving motorcycle, the distance of motorcycles is changing. But more like playing table tennis, the racket hits the ball at fix location and changes the speeds of reflected balls, which changes the time of flight of the ball. No matter in continuous wave or pulse wave or color ultrasound, when checking the velocity of blood flow, the ultrasound system always detect the reflected ultrasound pulses from the fixed locations where the ultrasound beams cross with blood vessels to calculate the shift of time of flight (TOF) of ultrasound pulses. So, the detecting the velocity of moving objects can be calculated based on the TOF shift.
One aspect of the invention, correcting the transmitting distance of ultrasound pulses can rectify the registration of detecting depth, which improves the quality of ultrasound images. During the transmission in the medium, the speed of ultrasound pulse will gradually reduce due to the loss of its energy caused by acoustic impedance. The current calculation of ultrasound reflecting depth is based on fixed ultrasound speed, which will cause miscalculation of reflecting depth due to the change of actual ultrasound speed, and distort the ultrasound images. Because the ultrasound speed is inversely correlated to acoustic impedance and attenuation coefficient, the ultrasound speed reducing coefficient could be used to correct the registration of detecting depth, which will improve the quality of images.
In another aspect of the invention, the thickness of activated piezoelectric crystals (PZT) decides the quantity of ultrasound pulses, which affects their penetrating depth. The penetrating depth of ultrasound pulses is not directly related to their frequencies, but related to their quantity. The thicker PZT is, the greater quantity the ultrasound pulses will be and deeper the penetrating depth will be. Because the frequency is directly proportional to the sound speed in PZT elements, selecting PZT elements with higher speed in the PZT elements will generate the ultrasound pulses with more density and higher frequency and greater quantity. So, the pulses with higher frequency and greater quantity have deeper penetrating ability, which will improve the quality of images for high frequency ultrasound.
Another aspect of the invention is detecting the velocity of moving objects by TOF shift of time domain analysis for continuous wave, pulse wave and color ultrasound. It is based on the speed changes of reflected ultrasound pulses by the moving objects, which change their TOF and TOF shift. The moving objects may change the rebounding forces to the ultrasound pulses. The velocity and angle of moving objects with ultrasound beams decide rebounding force. Faster forward velocity and/or greater angle of moving object with ultrasound beam will generate greater rebound force, which create greater reflecting speed of ultrasound pulses and result in shorter TOF and greater TOF shift. On the contrary, faster reversed velocity and/or smaller angle of moving object with ultrasound beam will reduce rebound force, which produce slower reflecting speed of ultrasound pulses and result in longer TOF and greater TOF shift. For continuous, pulse wave and color Doppler, The velocity of moving objects can be calculated based on the related TOF shift.
Another aspect of the invention is clarifying the mechanism of aliasing and the ways of completely correcting the aliasing for pulsed wave and color ultrasound. If the speed of moving object is too fast, which makes TOF excesses its aliasing limit, the ultrasound system will misinterpret the reflected ultrasound pulse and generate aliasing TOF. For forward moving object, the aliasing limit for TOF is less than the value of half of calculated TOF. If TOF is smaller than the aliasing limit, the ultrasound system will misinterpret the reflected ultrasound pulse and add a value of calculated TOF into actual TOF, which generates aliasing TOF. Then the aliasing TOF is greater than calculated TOF. So, aliasing TOF shift is below baseline, which represent the moving object toward reversed direction. For reversely moving object, its TOF aliasing limit is greater than the value of one and half calculated TOF. If the actual TOF is greater than the aliasing limit, the ultrasound system will subtract a value of calculated TOF from actual TOF. Then the aliasing TOF is smaller than calculated TOF. So, aliasing TOF shift is above the baseline, which represent the moving object as forward direction. A computer program is used to identify the aliasing TOF shift, and the corrected TOF shift can be also used to correct aliasing when TOF excesses its aliasing limit in pulse wave or color ultrasound no matter how fast the velocity of moving objects will be. Correcting aliasing also avoid the interference of aliasing to the disturbed flow.
Based on the speed reduction of ultrasound pulses during the transmission, the quantity of ultrasound pulses, and the TOF changes of ultrasound pulses by the velocity of moving objects, TOF shift can more accurately present the relationship between the TOF of ultrasound pulses and the velocity of moving objects, and it also better explains the effect of the velocity and angle of the moving objects on the ultrasound pulses. So, the calculated velocity of moving objects from TOF shift should be more accurate than the results from Doppler shift.
a is a schematic illustration of aliasing TOF shift for forward flow of pulsed wave ultrasound
b is a schematic illustration of corrected TOF shift for forward flow of pulsed wave ultrasound
a is a schematic illustration of aliasing TOF shift for reversed flow of pulsed wave ultrasound
b is a schematic illustration of corrected TOF shift for reversed flow of pulsed wave ultrasound
The Speed of Ultrasound Pulses Gradually Reduces During Transmission
The transmission of ultrasound energy in the medium is more like pulses, which contain their quantity and size. Nowadays, the ultrasound speed is considered as fixed in the same medium. But, actually the speed of ultrasound pulses is not fixed at the same speed as supposed during the transmission, and it will gradually reduce due to the acoustic impedance of transmitting medium. As the bullets shooting from machine gun, their speed is gradually reduced due to the loss of their energy caused by the resistance of air. But, the frequencies of bullets at any sites of trajectory keep the same. The transmission of ultrasound pulses has the similar mechanism. During the transmission, the speed of ultrasound pulses gradually reduces due to the loss of their energy caused by the acoustic impedance, which will finally exhausts the energy of the ultrasound pulses. The rate of its speed change is decided by attenuation coefficient and acoustic impedance. But, Ultrasound pulses keep the same frequency during the transmission, including reflected frequency.
Currently, the attenuation coefficient is directly proportional to the ultrasound frequency. The lower the frequency is, the smaller the attenuation coefficient will be.
Attenuation Coefficient (dB/cm)=frequency (MHz)/2
Total attenuation (dB)=attenuation coefficient×distance
As the frequency is inversely proportional to the PZT thickness, the more PZT thickness has lower frequency.
frequency=sound speed in PZT/2×PZT thickness
In lower frequency ultrasound, more PZT materials will be activated from more thickness of PZT, it means that higher quantitative ultrasound pulses are generated from these more activated PZT materials.
So, attenuation coefficient is actually decided by the quantity of ultrasound pulses, which is related the thickness of activated PZT. Like heavier ball with more ability of traveling distance, the ultrasound pulses with higher quantity will have lower attenuation coefficient, and have smaller reducing rate of its speed comparing to the ultrasound pulses with smaller quantity.
The acoustic impedance is decided by the density of medium and ultrasound speed in the medium.
Acoustic impedance (rayls)=density (kg/m3)×speed (m/s)
So, higher the speed of ultrasound pulse is, the greater the acoustic impedance will be, which consume more its energy during the transmission. As the energy transmission of acoustic pulses in the medium, the speed of ultrasound pulses should be directly related to its energy, and its speed will gradually reduce due to the loss of its energy during its transmission until the exhaustion of its energy.
Rectifying the Registration of Detecting Depth of Ultrasound Pulses can Improve the Quality of Images
One aspect of the invention is rectifying the errors of the registration of detecting depth due to speed reduction of ultrasound pulses. Because ultrasound speed is affected by acoustic impedance and attenuation coefficient, its speed will gradually reduce as it transmits in the medium. Nowadays, the calculated detecting depth is based on fixed general ultrasound speed in the medium, which will cause miscalculation of detecting depth due to the change of actual ultrasound speed, and distort the ultrasound images. The longer the ultrasound pulses travel, the slower the pulse speed will be. So, actually traveling depth of ultrasound pulses is smaller than calculated detecting depth because of the speed reduction of ultrasound during the transmission. As the reduction of ultrasound speed is directly correlated to acoustic impedance and attenuation coefficient. The ultrasound speed reducing coefficient could be used to correct the errors of calculated detecting depth. The distance shift of ultrasound pulses is directly related of the speed reducing coefficient and traveling time of ultrasound. V is the general speed of ultrasound pulses in the transmitting medium. For instance, the general ultrasound speed in soft tissues is 1540 meter/second. t is the traveling time from emitting to receiving the ultrasound pulses. Calculated depth is the depth based on general ultrasound speed and traveling time of ultrasound pulses between emitting to receiving.
Speed reducing coefficient=acoustic impedance×attenuation coefficient
Depth shift=speed reducing coefficient×t/2
Calculated detecting depth=V×t/2
Corrected detecting depth=calculated depth−depth shift
The Quantity of Ultrasound Pulses Affect their Penetrating Depth
In another aspect of the invention, creating the transducer with more thickness of PZT and faster speed of sound in PZT will generate the ultrasound pulses with higher frequency and higher quantity, which increase their penetrating depth and improve the quality of images. The ultrasound transducers contain piezoelectric (PZT) materials, which emit ultrasound pulses. In the pulsed wave transducer, the PZT thickness and the speed of sound in PZT are related to the transducer frequency. The more thickness and/or slower speed of sound in PZT will induce lower frequency. Actually thicker activated PZT elements will emit greater quantity of the pulses comparing thinner PZT transducer, which explains why the ultrasound pulses with lower frequency have greater penetrating depth. At the same time, increasing the speed of sound in PZT also increases the density of the ultrasound pulses, which can increase the frequency of transducer.
frequency=sound speed in PZT/2×PZT thickness
Moving Objects Will Change TOF and Generate TOF Shift for Ultrasound Pulses
Ultrasound pulses can be reflected by motionless or moving objects. Comparing to motionless objects, moving objects will change the rebound force to the ultrasound pulses. The velocity and angle of moving objects with ultrasound beams will generate rebounding force shift. As in the
The quantity of ultrasound pulses also affects their TOF and TOF shift. As the quantity of ultrasound pulses is directly related the PZT thickness, it is inversely related to the TOF shift. The ultrasound pulses with greater quantity have smaller speed changes of reflected pulses, which elongates its TOF and decreases TOF shift. On the contrary, smaller quantitative pulses have the greater speed changes of reflected pulses, which shortens its TOF and increases TOF shift.
The sound speed in PZT also affects the TOF shift. The higher speed of sound speed in PZT generates higher density of the pulses, which will shorten its TOF and increase its TOF shift.
So, one aspect of the invention is calculating the velocity of moving objects based on TOF shift for continuous or pulsed wave ultrasound. As mentioned above, the speed of ultrasound pulses will gradually reduce, and moving objects will generate rebounding force shift, which changes the speed of reflected ultrasound pulses and their TOF. Therefore, TOF shift can more accurately present the relationship between the velocity of moving objects and the characters of ultrasound pulses.
Calculating the Velocity of Moving Objects by TOF Shift of Continuous Wave Ultrasound
Currently, it is considered that the speed of ultrasound is fixed in the same medium during the transmission. The moving objects will change the frequency of reflected ultrasound waves. As forward moving objects will compress the reflected frequency, which is higher than the emitted frequency. Its Doppler shift is above the baseline. So, calculating continuous wave (CW) Doppler shift is based on the difference between reflected frequency and emitted frequency.
Doppler shift=reflected frequency−emitted frequency
Doppler shift=2×speed of objects×transducer frequency×cos θ/propagation speed
The present invention discloses that TOF shift in continuous wave ultrasound is the difference between the time of emitting period and the time of reflected period. As 101 in
emitted period=1/emitted frequency
reflected period=1/reflected frequency
reflected period=the time between previous and following reflected pulses
TOF shift=emitted period−reflected period
TOF shift=2×speed of objects×transducer frequency×cos θ/propagation speed
There are two PZT parts in CW ultrasound transducer. As in the
As 100 in
Calculating the Velocity of Moving Objects by TOF Shift of Pulse Wave and Color Ultrasound
there is only one PZT part in pulsed wave ultrasound transducer, which sends and receives ultrasound pulses. So, the transducer has to receive previous reflected pulses before sending following emitted pulses. In order to detect the velocity of moving objects, the gate or detecting depth must be set as 103 in
TOF shift=calculated TOF−actual TOF
TOF shift=2×speed of objects×transducer frequency×cos θ/propagation speed
The actual TOF is usually the detected time between emitting and receiving pulses by ultrasound system. But if the velocity of moving objects is too fast, and makes its TOF excesses its aliasing limit, the ultrasound system will misinterpret it and produce aliasing TOF and aliasing TOF shift, which present the moving objects as toward opposite direction.
For the forward moving object, its aliasing limit of TOF is less than half value of calculated TOF. if the actual TOF is less than half of calculated TOF, the ultrasound system will misinterpret the reflected pulse, and add a calculated TOF value in aliasing TOF, which is larger than calculated TOF as 104 in
Aliasing TOF=actual TOF+calculated TOF
Aliasing TOF shift=calculated TOF−aliasing TOF
Aliasing TOF shift=−actual TOF
So, in the invention, a computer program is designed to identify and correct the aliasing. As the value of TOF shift approaches the half value of calculated TOF, the computer program will compare the value o following TOF shift with the value of previous TOF shift. If the value of following TOF shift is located on opposite site of baseline to the value of previous TOF shift. There is a TOF shift. After identifying the aliasing TOF shift, the ultrasound system will rectify the registering corrected TOF shift by subtracting the value of aliasing TOF shift from calculated TOF (116 in
TOF shift=calculated TOF−actual TOF
Aliasing TOF shift=−actual TOF
corrected TOF shift=calculated TOF−|aliasing TOF shift|
After rectifying the registering errors of TOF shift, the value of corrected TOF shift will increase as the value of TOF decreases, which reestablish the continuation of profile of TOF shift (
For the reversely moving objects, the rebounding force is reduced, which decreases the reflected speed of ultrasound pulses and increases their TOF, which is greater than the value of calculated TOF. So, the value of TOF shift is below the baseline. The aliasing limit of TOF for reversely moving objects is the value of actual TOF larger than the value of one and half calculated TOF. If the value of actual TOF excesses its aliasing limit, the ultrasound system will misinterpret the reflected ultrasound pulses and subtract a calculated TOF value in aliasing TOF, which is smaller than calculated TOF. So, aliasing TOF shift will be above baseline, which misrepresents the moving objects from forward direction. As a result, the continuity of the profile of TOF shift is disrupted (
Aliasing TOF=actual TOF−calculated TOF
Aliasing TOF shift=calculated TOF−aliasing TOF
Aliasing TOF shift=2×calculated TOF−actual TOF
After identifying the aliasing TOF shift, the computer program will rectify the aliasing TOF shift by subtract the value of a calculated TOF from the value of aliasing TOF shift, which is based on following equations:
TOF shift=calculated TOF−actual TOF and
aliasing TOF shift=2×calculated TOF−actual TOF
correct TOF shift=aliasing TOF shift−calculated TOF
After correcting aliasing TOF shift, their correct registration will be established, which continues the profile of its TOF shift (
Increasing the Quantity of Ultrasound Pulses or Reducing Detecting Depth Helps Improving Aliasing
Increasing the quantity of ultrasound pulses will decrease the speed changes of reflected pulses, which increase their TOF and delays their value reaching their aliasing limits.