Benefit is claimed to German Patent Application No. 102020115648.0, filed on Jun. 12, 2020 and German Patent Application No. 102020132517.7, filed on Dec. 7, 2020; the contents of both of which are incorporated by reference herein in their entirety.
The present invention relates to a camera. International patent application WO2013/007612 A1 describes a light field camera for fundus imaging comprising a lens array. The focal length of the lenses of the lens array is constant.
The camera described herein is arranged to capture images or videos. In particular the camera is a funds camera. For example, the camera is a non-mydriatic fundus camera, which enables retinal photography without pharmacologic dilation of the pupil. Non-mydriatic imaging is effective through pupils with a diameter of at least 2.0 mm. The fundus camera makes use of the retina's reflective properties to show details and store images that are superior to slit lamps and other commonly-used tools. Advantageously, the fundus camera does not require pupil dilation in the majority of cases and is painless for patients
As shown in
The camera 1 comprises an aperture 10 having an opaque element 13 with multiple through holes 14 and a plurality of tunable lenses 12. Each tunable lens is arranged to one of the through holes. In particular a tunable lens arranged in each through hole.
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A shown in
The illumination device is arranged on a side of the aperture, facing away from the sensor element. The tunable lenses are arranged in a common plane. The illumination device is arranged to illuminate a region of interest on a side of the aperture facing away from the sensor element. In particular, the camera is arranged to capture images of an eye which is arranged in the region of interest. The sensor is arranged to capture a portion of the light reflected in the region of interest, wherein the portion of the reflected light passes through the tunable lenses and the through holes.
For example, each tunable lens comprises a tunable surface or at least two tunable surfaces, wherein the refractive power is tunable by changing the curvature of the tunable surface or the tunable surfaces. The tunable surface may be formed by a membrane which is arranged adjacent to a volume filled with a liquid, wherein the curvature of the tunable surface is altered by moving the liquid. The volume of the tunable lenses is arranged in the through holes of the aperture and the aperture delimits the volume at least partially. In particular, the plurality of tunable lenses comprises a common membrane which extends continuously over the plurality of through holes. The refractive power of the tunable lenses is tunable in a range −40 diopters to +30 diopters.
As shown in
In particular, the aperture comprises blocking elements 19. The blocking elements are arranged between the opaque element and the image sensor. The blocking elements are made from an opaque material. As shown in
For example, the camera has a single field of view range of at least 200°. In particular, eye position guidance allows to enlarge the field of view. An image captured by eye position guidance has a field of view of at least 240°.
According to one embodiment, the camera comprises a focus unit 30. The focus unit is arranged to tune the tunable lenses to a dedicated tuning state or to define a time span in which an image is captured by means of the sensor element. In particular the focus unit is arranged to identify patterns. Thereby the focus unit may identify the retina and the choroid of a human eye. In particular the focus unit is arranged to control the camera, so that images of the choroid and the retina are captured automatically, in particular essentially simultaneously.
According to one embodiment the camera is arranged for external eye and anterior segment imaging.
According to one embodiment, the camera has an automatic mode, wherein the focus unit automatically controls the focus plane in which an image is captured. Furthermore, the camera may have a manual mode, wherein the user defines in which focus plane an image is captured.
According to one embodiment, the optical power of the tunable lenses is tunable in a range from −13 diopters to +12 diopters.
According to one embodiment, the camera is arranged to capture an image in less than 1 second. In particular said image may consist of multiple sub-images, wherein the sub-images are taken at different tuning states of the tunable lenses. The image may be taken without considering light in the wavelength range of red light. In particular, the illumination unit does not emit light in a wavelength rang of red light or the aperture or the image senor comprise a sensor, blocking light in the red wavelength range from being captured. In particular the image captured may be a monochromatic image. In particular, the camera is arranged to detect autofluorescence. Autofluorescence is the natural emission of light by biological structures such as mitochondria and lysosomes when they have absorbed light, and is used to distinguish the light originating from artificially added fluorescent markers (fluorophores). The most commonly observed autofluorescencing molecules are NADPH and flavins; the extracellular matrix can also contribute to autofluorescence because of the intrinsic properties of collagen and elastin. Generally, proteins containing an increased amount of the amino acids tryptophan, tyrosine and phenylalanine show some degree of autofluorescence.
The tunable lenses of the camera work similar to the refractive optical element described in connection with the display unit disclosed in the German patent application 10 2020 115 648.0 which content is hereby incorporated by reference.
According to a first aspect, the camera comprises a sensor element, and an aperture, wherein
According to a second aspect the camera is a fundus camera.
According to a third aspect, the illumination device is arranged to illuminate a region of interest on a side of the aperture facing away from the sensor element, wherein the sensor is arranged to capture a portion of the light reflected in the region of interest, wherein the portion of the reflected light passes through the tunable lenses and the through holes.
According to a fourth aspect the illumination device comprises an LED which is arranged between two of the through holes and in particular which is fixedly attached to the aperture.
According to a fifth aspect, the tunable lenses are arranged in a common plane.
According to a sixth aspect, the tunable lenses are arranged at the corner points of an imaginary repetitive hexagonal line pattern, at the corner points of an imaginary repetitive rectangular line pattern or along the lines of an imaginary concentric circular pattern.
According to a seventh aspect the tunable lenses are arranged in the through holes of the aperture respectively.
According to an eighth aspect, the tunable lens comprises a tunable surface or at least two tunable surfaces, wherein the refractive power is tunable by changing the curvature of the tunable surface or the tunable surfaces.
According to a ninth aspect, the tunable surface is formed by a membrane which is arranged adjacent to a volume filled with a liquid, wherein the curvature of the tunable surface is altered by moving the liquid.
According to a tenth aspect, the volume of the tunable lenses is arranged in the through holes of the aperture and the aperture delimits the volume at least partially.
According to an eleventh aspect, the plurality of tunable lenses comprises a common membrane which extends continuously over the plurality of through holes.
According to a twelfth aspect refractive power of the tunable lenses is tunable in a range −40 diopters to +30 diopters.
According to a thirteenth aspect, the a method for operating a camera comprising a sensor element and an aperture having a plurality of through holes and a plurality of tunable lenses is provided, wherein the refractive optical element (12) has a refractive power, which is tunable, comprising the steps of,
According to a fourteenth aspect the sensor element comprises multiple subregions, wherein the aperture images different sections of the region of interest in the subregions, and the method comprises the method steps a1) and b1), wherein the time span in which each subregion captures the image is selected independently.
According to a fifteenth aspect the camera is a fundus camera which is arranged to capture an image of a mammal's eye, wherein the method comprises the method steps a1) and b1) and at least one subregion captures an image of the retina and at least one subregion captures an image of the choroid during one period of the oscillation of the oscillation of the tunable lenses, or the method comprises the method steps a2) and b2) and at least one subregion captures an image of the retina and at least one subregion captures an image of the choroid simultaneously.
According to a sixteenth aspect in method step a1) the refractive power is tuned with a frequency of at least 45 Hz, in particular at least 60 Hz, and an amplitude of at least 5 diopters in particular at least 10 diopters.
According to a seventeenth aspect the refractive power is set to an offset value, and the refractive power oscillates around said offset value in method step a1).
According to an eighteenth aspect, the offset value is between −40 and +30 diopters and the offset value depends on the ametropia of the person using the camera.
According to a nineteenth aspect, the camera comprises a focus unit, which is arranged to automatically adjust the tuning state of the tunable lenses and/or which is arranged to automatically select a time span.
According to a twentieth aspect the camera is a fundus camera, the focus unit is arranged to identify the retina and the choroid, the focus unit is arranged to adjust the tuning state of the tunable lenses and/or the time span to capture an image so that at least one of the subregions captures an image of the retina and at least one of the subregions captures an image of the choroid.
1 Camera
2 Human eye
10 Aperture
11 Illumination unit
12 Tunable lens
13 Opaque element
14 Through hole
122 Membrane
121 Lens shaper
123 Liquid volume
19 Blocking element
20 Image sensor
21 Subsection
30 Focus unit
Number | Date | Country | Kind |
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102020115648.0 | Jun 2020 | DE | national |
102020132517.7 | Dec 2020 | DE | national |