The present invention concerns implantable heart monitors, such as defibrillators and cardioverters, particularly structures and methods for capacitors in such devices.
Since the early 1980s, thousands of patients prone to irregular and sometimes life-threatening heart rhythms have had miniature heart monitors, particularly defibrillators and cardioverters, implanted in their bodies. These devices detect onset of abnormal heart rhythms and automatically apply corrective electrical therapy, specifically one or more bursts of electric current, to hearts. When the bursts of electric current are properly sized and timed, they restore normal heart function without human intervention, sparing patients considerable discomfort and often saving their lives.
The defibrillator or cardioverter includes a set of electrical leads, which extend from a sealed housing into the walls of a heart after implantation. Within the housing are a battery for supplying power, monitoring circuitry for detecting abnormal heart rhythms, and a capacitor for delivering bursts of electric current through the leads to the heart.
The capacitor can take the form of a flat aluminum electrolytic capacitor. Flat capacitors include a stack of flat capacitor elements, with each element including one or more separators between two sheets of aluminum foil. The capacitor elements, each of which has an individual capacitance (or energy-storage capacity) proportional to the surface area of the aluminum foil, are connected together to provide a total capacitance. The stack of capacitor elements is housed within an aluminum capacitor case which is filled with electrolyte.
The capacitor includes one or more metal wires, known as feedthroughs, which connect the capacitor elements to defibrillator or cardioverter circuitry located outside the case. A feedthrough reaches the outside of the case through a hole in the case called a feedthrough hole. After the capacitor elements are assembled within the capacitor case and the feedthrough is inserted through the feedthrough hole, manufacturers insulate the feedthrough from the case and seal the feedthrough hole. This involves, for instance, assembling an insulating sleeve, a nut, a gasket and/or other hardware around the feedthrough wire.
Thus, assembling the feedthrough, insulating the feedthrough, and sealing the feedthrough is a complex, time-consuming process.
To address these and other needs, the inventors have devised new capacitor structures and methods. An exemplary capacitor includes a case containing a capacitor stack. A coupling member having a base surface is directly attached to the capacitor stack. A feedthrough conductor has a portion which extends through a feedthrough hole in the case and into a mounting hole in the coupling member. The capacitor includes a sealing member adjacent the feedthrough hole and the feedthrough conductor for sealing the feedthrough hole.
One option provides an exemplary feedthrough assembly which includes a plug having a hole and a feedthrough conductor mounted within the hole. The feedthrough conductor has a diameter approximately equal to or larger than the plug hole diameter, thus sealing the feedthrough hole without requiring any epoxy or excess hardware.
Among other advantages, the relatively uncomplicated feedthrough structure of the exemplary capacitor provides for easier manufacturing and more reliable capacitors. Other facets of the invention include various implantable medical devices, such as pacemakers, defibrillators, and cardioverters, incorporating one or more features of the novel capacitors.
The following detailed description, which references and incorporates the figures, describes and illustrates one or more specific embodiments of the invention. These embodiments, offered not to limit but only to exemplify and teach the invention, are shown and described in sufficient detail to enable those skilled in the art to practice the invention. Thus, where appropriate to avoid obscuring the invention, the description may omit certain information known to those of skill in the art.
Case 101 includes a feedthrough hole 107 which is drilled, molded, or punched in a portion of a wall of case 101. Feedthrough hole 107 is in part defined by an edge 107a which outlines the feedthrough hole within case 101. Feedthrough hole 107 provides a passage for connecting feedthrough assembly 103 to circuitry outside of case 101. In some embodiments, case 101 includes two or more feedthrough holes for providing a second or third feedthrough assembly.
Feedthrough assembly 103 and terminal 104 connect capacitor elements to outside circuitry. In the exemplary embodiment, feedthrough assembly 103 extends through feedthrough hole 107 and is insulated from case 101. Terminal 104 is directly connected to case 101. Alternatively, in some embodiments, the capacitor incorporates other connection methods, depending on other design factors. In various embodiments, two or more insulated feedthrough assemblies are employed.
In the exemplary embodiment, sealing member 105, such as an epoxy, is deposited around feedthrough hole 107 and feedthrough assembly 103 to insulate feedthrough assembly 103 from case 101 and to seal an electrolyte within the case. An exemplary epoxy is a two-part epoxy manufactured by Dexter Hysol. This includes a casting resin compound (manufacturer No. EE 4183), a casting compound (manufacturer No. EE 4215), and a hardener (manufacturer No. HD 3404). The exemplary two-part epoxy is mixed in a ratio of hardener=0.055*casting resin. The mixture is cured at 0.5 hours at 60 degrees Celsius or 1.5 hours at room temperature. Another exemplary epoxy is a UV cure epoxy such as manufactured by Dymax, Inc., which can be cured using an Acticure (manufactured by GenTec) ultraviolet curing system at 7 W/cm2 at a distance of 0.25″ for approximately 10 seconds.
In one embodiment, the sealing member provides a non-hermetic seal. In one embodiment, the sealing member includes an elastic plug which will be discussed in further detail below.
Each anode includes one or more anode members in a stack. These anodes and cathodes are foil structures and can be made from aluminum, tantalum, hafnium, niobium, titanium, zirconium, and combinations of these metals. A major surface of each anode foil is roughened to increase its effective surface area. This increases the capacitive effect of the foil with no relative increase in volume. However, none of the embodiments are limited to any particular foil composition or class of foil compositions.
The separators include one or more electrolyte impregnated separators between each anode and each cathode. In the exemplary embodiment, each separator consists of two kraft papers impregnated with an electrolyte. The electrolyte can be any suitable electrolyte for an electrolytic capacitor, such as an ethylene-glycol base combined with polyphosphates, ammonium pentaborate, and/or an adipic acid solute. Other embodiments incorporate different numbers and arrangements of anodes, cathodes, and separators.
In the exemplary embodiment, each cathode of capacitor stack 202 is connected to the other cathodes and to conductive case 101. Terminal 104 is attached to case 101 to provide a cathode connection to outside circuitry. In some embodiments, the cathode is coupled to a feedthrough conductor extending through a feedthrough hole.
In the exemplary embodiment, each anode is connected to the other anodes of the capacitor. Attached to the anode of each capacitor element 205a-205n is a conductive tab or connection member 201. In one embodiment, each connection member 201 includes an edge face 215 which is substantially perpendicular to the major surface of the anodes. Edge face 215 provides a conductive surface for connecting each capacitor element 205a-205n to feedthrough assembly 103. The anode connection members 201 are welded or crimped together and are coupled to feedthrough assembly 103 for electrically connecting the anode to circuitry outside the case. In some embodiments, the cathode is coupled to a feedthrough assembly and the anode is connected to the case. In other embodiments, both the anode and the cathode are connected to feedthroughs.
In one embodiment, connection members 201 are edge-welded to each other as discussed in U.S. patent application Ser. No. 09/706,518, filed Nov. 3, 2000, now issued as U.S. Pat. No. 6,687,118, which is incorporated herein by reference in its entirety. Edge-welding the connection members provides a flat connection surface 216, which includes one or more edge faces 215 of connection members 201. In some embodiments, connection members 201 are crimped, soldered, and/or connected by an electrically conductive adhesive.
In the exemplary embodiment, feedthrough assembly 103 includes two members, a feedthrough wire or conductor 203 and a coupling member 204. Coupling member 204 is attached to capacitor stack 202 at connection surface 216, and feedthrough conductor 203 is attached to coupling member 204. In the exemplary embodiment, coupling member 204 partially extends through feedthrough hole 107.
Feedthrough conductor 203 is a conductive member which can include material such as nickel, gold plated nickel, platinum, aluminum, or other conductive metal. Feedthrough conductor 203 has a proximal end portion 217 attached to coupling member 204 and a distal end portion 218 for attaching to circuitry outside the case, such as defibrillator or cardioverter circuitry. In the exemplary embodiment, feedthrough conductor 203 has a diameter of approximately 0.016″ (0.4064 mm). However, other embodiments have feedthrough conductors of different diameters and/or non-circular cross-sections.
In the exemplary embodiment, coupling member 204 is a high-purity aluminum member which is able to withstand the high voltages generated within the capacitor case. In other embodiments it is made from another conductive material compatible with the capacitor stack. Coupling member 204 includes a base 404 and a holding tube 407. On one side of base 404 is a planar surface 405 for attaching to the planar surface 216 presented by edge-welded connection members 201.
Referring again to
Holding tube 407 is located on the opposing side of base 404 from surface 405. Tube 407 is a cylindrical member having an outer diameter dimensioned to fit within feedthrough hole 107. Tube 407 has a mounting section such as mounting hole 401 defined in part by an inner surface 402 of holding tube 406 which is generally perpendicular to base surface 405. Hole 401 is located down an axial portion of the tube.
Mounting section or hole 401 is for receiving proximal end portion 217 of feedthrough conductor 203. The surface of feedthrough conductor 203 contacts inner surface 402. In the exemplary embodiment, hole 401 is approximately 0.016″ (0.4064 mm) in diameter. Alternatively, its diameter can conform with the size of conductor 203 so that feedthrough conductor 203 can matably fit within the hole. In the exemplary embodiment, coupling member 204 has a height 204h of approximately 0.085″ (2.519 mm). Other embodiments range from 0.050″ to 0.100″ or higher. Some embodiments provide a height of greater than 0.100″.
In the exemplary embodiment, inner surface 402 of coupling member 204 is a curved surface defining an annular connection member. Crimp 502 compresses and deforms opposing surfaces of annular inner surface 402 to contact conductor 203. In the exemplary embodiment, the opposing surfaces of inner surface 402 are separated by a first distance prior to being crimped and separated by a second distance, smaller than the first distance, after being crimped.
In this embodiment, plug 106 is a double-flanged plug. Plug 106 includes a first flange 108. First flange 108 includes a first surface 108a which faces the inner surface of case 101. When the capacitor begins to become pressurized, pressure against a second surface 108b forces first surface 108a against the case. Thus, flange 108 creates a seal against the inner surface of case 101.
In this embodiment, plug 106 includes a second flange 109. Flange 109 includes a surface which faces the outer surface of case 101.
Plug 106 also includes a plug portion 110 which is located between and defined by first flange 108 and second flange 109. Portion 110 has a smaller diameter than either flange 108 and/or 109. Case edge 107a confronts plug 106 at portion 110. In this embodiment, portion 110 has a normal, unstressed outer diameter approximately equal to the diameter of feedthrough hole 107. In some embodiments, the unstressed outer diameter is larger than the diameter of feedthrough hole 107. In some embodiments, the unstressed outer diameter is smaller than hole 107. As one example, in this embodiment flange 108 has a diameter of approximately 0.080 inches and portion 110 has a diameter of approximately 0.060 inches.
Plug 106 also includes a central passage or hole 1102. In one embodiment, hole 1102 is axially located through the center of plug 106 and has an unstressed diameter 1102d which is smaller than or equal to a diameter 103d of a portion of feedthrough member 103 which is mounted within hole 1102. In various embodiments, diameter 1102d may range from approximately 0.015 inches to approximately 0.033 inches. In other embodiments, diameter 1102d is smaller than 0.015 inches. In some embodiments it is greater than 0.033 inches. Other embodiments vary the hole size depending on the size of the feedthrough conductor used. In some embodiments, when a feedthrough member such as coupling member 204 is inserted through hole 1102, an interference fit seal is developed between the feedthrough member and the plug. In other embodiments, hydrogen gas can escape along the feedthrough member/plug 106 border.
In one embodiment, plug 106 is made from a compressible, elastic material such as rubber, plastic, thermoplastic, or other elastic or elastomeric material. In one embodiment, when plug 106 is mounted within feedthrough hole 107 and feedthrough member 103 is mounted within hole 1102, plug portion 110 is compressed between assembly 103 and edge 107a of feedthrough hole 107 and the plug exerts a radial force on edge 107a of the feedthrough hole. This forces or compresses plug 106 into an interference or compression fit between feedthrough hole edge 107a and member 204, thus helping to seal electrolyte solution within case 101. In other embodiments, the diameter of portion 110 is smaller than hole 107 and an interference fit between feedthrough hole edge 107a and member 204 is not created.
In one embodiment, as noted above, flange 108 provides a sealing means for helping seal electrolyte within the case. Accordingly, in some embodiments, when the diameter of portion 110 is smaller than hole 107 and an interference fit between feedthrough hole edge 107a and member 204 is not created, only flange 108 provides a sealing means between case 101 and plug 106. Advantageously, the seal or seals are formed automatically. Thus, in one embodiment, assembling and tightening a screw or other extraneous hardware is not required to seal the capacitor.
In one embodiment, second flange 109 provides support for mounting plug 106 within hole 107. For instance, when plug 106 is mounted in hole 107, flanges 108 and 109 each help hold plug 106 in place once it is mounted, but before the coupling member 204 is inserted through hole 1102. This aides the manufacturing process.
In one embodiment second flange 109 includes a tapered section wherein an outer portion 109a of flange 109 has a smaller diameter than an inner portion 109b. The tapered shape of flange 109 aids in inserting plug 106 into hole 107. Some embodiments omit the tapered shape and flange 109 has a uniform outer diameter. Other embodiments provide a tapered shape for first flange 108. Other embodiments provide tapered sections on both flanges.
In this embodiment, flange 108 has a larger diameter than flange 109. In some embodiments, the two flanges have substantially equal diameters. In further embodiments, flange 109 has a larger diameter than flange 108.
Some embodiments omit either or both of flanges 108 and 109. For instance, in some embodiments plug 106 has a generally cylindrical shape. In other embodiments, plug 106 has an hour-glass shape or other shape which closely fits within feedthrough hole 107. In some embodiments, plug 106 is a mass of elastic material with a dimension approximately equal to or larger than the width of feedthrough hole 107.
In one embodiment, plug 106 seals the electrolyte within capacitor case 101, but it does not provide a hermetic seal. Hydrogen is created during consumption of water from the electrolyte and continues to be formed throughout the life of the capacitor. This can cause a hermetically sealed capacitor case to bulge outward from the hydrogen gas production within, thus risking long-term device reliability due to shorting.
Accordingly, in one embodiment plug 106 permits out-gassing of hydrogen gas, thus alleviating any problems. For instance, in one embodiment, flange 108 creates a seal to the inner wall of the case 101. A pathway for the gas to escape is then present along the border between coupling member 204 and plug 106.
In one embodiment, narrow section 132b provides an O-ring type interference fit for a feedthrough member such as coupling member 204. In this embodiment, narrow section 132b is generally located within second flange 129. Other embodiments locate the narrow section within central portion 130. Other embodiments locate the narrow section within first flange 128. By way of example, in one embodiment, the nominal diameters of sections 132a and 132c is approximately 0.032 inches, and the diameter of narrow section 132b is 0.026 inches.
Referring again to
Heart monitor 1300 includes a lead system 1303, which after implantation electrically contact strategic portions of a patient's heart. Shown schematically are portions of monitor 1300 including a monitoring circuit 1302 for monitoring heart activity through one or more of the leads of lead system 1303, and a therapy circuit 1301 for delivering electrical energy through one or more of the leads to a heart. Monitor 1300 also includes an energy storage component, which includes a battery 1304 and incorporates at least one capacitor 1305 having one or more of the features of the exemplary capacitors described above.
In addition to implantable heart monitor and other cardiac rhythm management devices, one or more teachings of the present invention can be incorporated into photographic flash equipment or other devices using flat or cylindrical capacitors. Indeed, these teachings of the invention are pertinent to any application where high-energy, high-voltage, or space-efficient capacitors are desirable.
In furtherance of the art, the inventors have devised a capacitor which includes, in an exemplary embodiment, a coupling member attached to a capacitor stack of the capacitor, a feedthrough conductor attached to the coupling member and extending through the feedthrough hole of the capacitor, and means for sealing the feedthrough hole. One embodiment provides a feedthrough assembly which includes a plug having a hole and a feedthrough conductor mounted within the hole. The feedthrough conductor has a diameter approximately equal to or larger than the plug hole diameter, thus sealing the feedthrough hole without requiring any excess hardware. Among other advantages, the relatively uncomplicated feedthrough structure of the exemplary embodiments provides for easier manufacturing and more reliable capacitors.
The embodiments described above are intended only to illustrate and teach one or more ways of practicing or implementing the present invention, not to restrict its breadth or scope. The actual scope of the invention, which embraces all ways of practicing or implementing the teachings of the invention, is defined only by the following claims and their equivalents.
This application is a division of application Ser. No. 10/846,805, filed on May 14, 2004, now issued as U.S. Pat. No. 7,177,692, which is a division of application Ser. No. 09/706,579, filed on Nov. 3, 2000, now issued as U.S. Pat. No. 7,107,099, the specifications of which are incorporated herein by reference. This application is related to application Ser. No. 09/706,447, filed on Nov. 3, 2000, now issued as U.S. Pat. No. 6,699,265, which is incorporated herein by reference in its entirety.
Number | Name | Date | Kind |
---|---|---|---|
1474486 | Macpherson | Nov 1923 | A |
1931043 | Taylor | Oct 1933 | A |
2555326 | Doughty, Jr. | Jun 1951 | A |
3150301 | Schils et al. | Sep 1964 | A |
3389311 | Rayno | Jun 1968 | A |
3424857 | Miller et al. | Jan 1969 | A |
3643168 | Manicki | Feb 1972 | A |
3686535 | Piper | Aug 1972 | A |
3686538 | Webster | Aug 1972 | A |
3723926 | Thomas et al. | Mar 1973 | A |
3777570 | Thomas et al. | Dec 1973 | A |
3803457 | Yamamoto | Apr 1974 | A |
3826143 | Thomas et al. | Jul 1974 | A |
3828227 | Millard et al. | Aug 1974 | A |
3859574 | Brazier | Jan 1975 | A |
3938228 | Kemkers et al. | Feb 1976 | A |
4045644 | Shafer et al. | Aug 1977 | A |
4047790 | Carino | Sep 1977 | A |
4086148 | Badia | Apr 1978 | A |
4088108 | Hager | May 1978 | A |
4131935 | Clement | Dec 1978 | A |
4171477 | Funari | Oct 1979 | A |
4247883 | Thompson et al. | Jan 1981 | A |
4267565 | Puppolo et al. | May 1981 | A |
4307142 | Blitstein et al. | Dec 1981 | A |
4394713 | Yoshida | Jul 1983 | A |
4571662 | Conquest et al. | Feb 1986 | A |
4782340 | Czubatyj et al. | Nov 1988 | A |
4931899 | Pruett | Jun 1990 | A |
5041942 | Carrico | Aug 1991 | A |
5131388 | Pless et al. | Jul 1992 | A |
5333095 | Stevenson et al. | Jul 1994 | A |
5377073 | Fukaumi et al. | Dec 1994 | A |
5439760 | Howard et al. | Aug 1995 | A |
5471087 | Buerger, Jr. | Nov 1995 | A |
5507966 | Liu | Apr 1996 | A |
5522851 | Fayram | Jun 1996 | A |
5527346 | Kroll | Jun 1996 | A |
5554178 | Dahl et al. | Sep 1996 | A |
5584890 | MacFarlane et al. | Dec 1996 | A |
5628801 | MacFarlane et al. | May 1997 | A |
5634938 | Swanson et al. | Jun 1997 | A |
5658319 | Kroll | Aug 1997 | A |
5660737 | Elias et al. | Aug 1997 | A |
5716729 | Sunderland et al. | Feb 1998 | A |
5754394 | Evans et al. | May 1998 | A |
5779699 | Lipson | Jul 1998 | A |
5779891 | Andelman | Jul 1998 | A |
5800724 | Habeger et al. | Sep 1998 | A |
5801917 | Elias | Sep 1998 | A |
5814082 | Fayram et al. | Sep 1998 | A |
5867363 | Tsai et al. | Feb 1999 | A |
5901867 | Mattson | May 1999 | A |
5908151 | Elias | Jun 1999 | A |
5922215 | Pless et al. | Jul 1999 | A |
5926357 | Elias et al. | Jul 1999 | A |
5926362 | Muffoletto et al. | Jul 1999 | A |
5930109 | Fishler | Jul 1999 | A |
5949638 | Greenwood, Jr. et al. | Sep 1999 | A |
5950131 | Vilmur | Sep 1999 | A |
5963418 | Greenwood, Jr. et al. | Oct 1999 | A |
5968210 | Strange et al. | Oct 1999 | A |
5973906 | Stevenson et al. | Oct 1999 | A |
5983472 | Fayram et al. | Nov 1999 | A |
6002969 | Machek et al. | Dec 1999 | A |
6006133 | Lessar et al. | Dec 1999 | A |
6009348 | Rorvick et al. | Dec 1999 | A |
6032075 | Pignato et al. | Feb 2000 | A |
6040082 | Haas et al. | Mar 2000 | A |
6042624 | Breyen et al. | Mar 2000 | A |
6052625 | Marshall | Apr 2000 | A |
6094788 | Farahmandi et al. | Aug 2000 | A |
6099600 | Yan et al. | Aug 2000 | A |
6104961 | Conger et al. | Aug 2000 | A |
6110233 | O'Phelan et al. | Aug 2000 | A |
6117194 | Strange et al. | Sep 2000 | A |
6118651 | Mehrotra et al. | Sep 2000 | A |
6141205 | Nutzman et al. | Oct 2000 | A |
6157531 | Breyen et al. | Dec 2000 | A |
6184160 | Yan et al. | Feb 2001 | B1 |
6191931 | Paspa et al. | Feb 2001 | B1 |
6212063 | Johnson et al. | Apr 2001 | B1 |
6249423 | O'Phelan et al. | Jun 2001 | B1 |
6249709 | Conger et al. | Jun 2001 | B1 |
6256542 | Marshall et al. | Jul 2001 | B1 |
6259954 | Conger et al. | Jul 2001 | B1 |
6275372 | Vassallo et al. | Aug 2001 | B1 |
6275729 | O'Phelan et al. | Aug 2001 | B1 |
6283985 | Harguth et al. | Sep 2001 | B1 |
6297943 | Carson | Oct 2001 | B1 |
6299752 | Strange et al. | Oct 2001 | B1 |
6321114 | Nutzman et al. | Nov 2001 | B1 |
6324049 | Inagawa et al. | Nov 2001 | B1 |
6326587 | Cardineau et al. | Dec 2001 | B1 |
6375688 | Akami et al. | Apr 2002 | B1 |
6380577 | Cadwallader | Apr 2002 | B1 |
6388866 | Rorvick et al. | May 2002 | B1 |
6402793 | Miltich et al. | Jun 2002 | B1 |
6409776 | Yan et al. | Jun 2002 | B1 |
6442015 | Niiori et al. | Aug 2002 | B1 |
6451073 | Farahmandi et al. | Sep 2002 | B1 |
6477037 | Nielsen et al. | Nov 2002 | B1 |
6493212 | Clarke et al. | Dec 2002 | B1 |
6509588 | O'Phelan et al. | Jan 2003 | B1 |
6522525 | O'Phelan et al. | Feb 2003 | B1 |
6556863 | O'Phelan et al. | Apr 2003 | B1 |
6571126 | O'Phelan et al. | May 2003 | B1 |
6585152 | Farahmandi et al. | Jul 2003 | B2 |
6628505 | Andelman | Sep 2003 | B1 |
6674634 | O'Phelan et al. | Jan 2004 | B2 |
6684102 | O'Phelan et al. | Jan 2004 | B1 |
6687118 | O'Phelan et al. | Feb 2004 | B1 |
6699265 | O'Phelan et al. | Mar 2004 | B1 |
6709946 | O'Phelan et al. | Mar 2004 | B2 |
6763265 | O'Phelan et al. | Jul 2004 | B2 |
6795729 | Breyen et al. | Sep 2004 | B1 |
6833987 | O'Phelan | Dec 2004 | B1 |
6885548 | Nyberg | Apr 2005 | B2 |
6885887 | O'Phelan et al. | Apr 2005 | B2 |
6957103 | Schmidt et al. | Oct 2005 | B2 |
6985351 | O'Phelan et al. | Jan 2006 | B2 |
6990375 | Kloss et al. | Jan 2006 | B2 |
6999304 | Schmidt et al. | Feb 2006 | B2 |
7072713 | O'Phelan et al. | Jul 2006 | B2 |
7079897 | Sun et al. | Jul 2006 | B2 |
7107099 | O'Phelan et al. | Sep 2006 | B1 |
7120008 | Sherwood | Oct 2006 | B2 |
7154739 | O'Phelan | Dec 2006 | B2 |
7157671 | O'Phelan et al. | Jan 2007 | B2 |
7177692 | O'Phelan et al. | Feb 2007 | B2 |
7180727 | Poplett | Feb 2007 | B2 |
7190569 | O'Phelan et al. | Mar 2007 | B2 |
7190570 | Schmidt et al. | Mar 2007 | B2 |
7221556 | Schmidt et al. | May 2007 | B2 |
20030072124 | O'Phelan et al. | Apr 2003 | A1 |
20030195568 | O'Phelan et al. | Oct 2003 | A1 |
20040019268 | Schmidt et al. | Jan 2004 | A1 |
20040114311 | O'Phelan et al. | Jun 2004 | A1 |
20040127952 | O'Phelan et al. | Jul 2004 | A1 |
20040193221 | O'Phelan et al. | Sep 2004 | A1 |
20050017888 | Sherwood et al. | Jan 2005 | A1 |
20050052825 | O'Phelan | Mar 2005 | A1 |
20060009808 | Schmidt et al. | Jan 2006 | A1 |
20060012942 | Poplett | Jan 2006 | A1 |
20060107506 | Doffing et al. | May 2006 | A1 |
20060152887 | Schmidt et al. | Jul 2006 | A1 |
20060174463 | O'Phelan et al. | Aug 2006 | A1 |
20060247715 | Youker | Nov 2006 | A1 |
20060257726 | Kelley et al. | Nov 2006 | A1 |
Number | Date | Country |
---|---|---|
0224733 | Jun 1987 | EP |
825900 | Dec 1959 | GB |
2132019 | Jun 1984 | GB |
05-074664 | Mar 1993 | JP |
WO-9827562 | Jun 1998 | WO |
WO-9951302 | Oct 1999 | WO |
WO-9951302 | Oct 1999 | WO |
WO-0019470 | Apr 2000 | WO |
WO-0237515 | May 2002 | WO |
WO-2006002148 | Jan 2006 | WO |
Number | Date | Country | |
---|---|---|---|
20070118182 A1 | May 2007 | US |
Number | Date | Country | |
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Parent | 10846805 | May 2004 | US |
Child | 11668109 | US | |
Parent | 09706579 | Nov 2000 | US |
Child | 10846805 | US |