Carlsson, A., et al., Neurotransmitter Interactions in Schizophrenia -Therapeutic Implications, Biol. Psychiatry 1999; 46:1388-1395. |
Wettstein, J., et al., Selectivity of Action of Typical and Atypical Anti-Psychotic Drugs as Antagonists of the Behavioral Effects of 1-[2,5-Dimethoxy-4-lodophenyl]-2-Aminopropane (DOI), Prog. Neuroo-Psychophamacol. & Biol. Psychiat, 1999, vol. 23, pp. 533-544. |
Abi-Dargham, A., et al., Increased Baseline Occupancy of D2 Receptors by Dopamine in Schizophrenia, PNAS, Jul. 2000, vol. 97, No. 14, 8104-8109. |
Veenstra-Vanderweele, J. et al., Pharmacogenetics and the Serotonin System: Initial Studies and Future Directions, European Journal of Pharmacology 410 (2000), 165-181. |
Lieberman, J., et al., Serotonergic Basis of Antipsychotic Drug Effects in Schizophrenia, Biol. Psychiatry, 1998, 44, 1099-1117. |
Aghajanian, G., et al., Serotonin Model of Schizophrenia: Emerging Role of Glutamate Mechanisms, Brain Research Reviews 31, (2000), 302-312. |
Yan, Q., Activation of 5-HT 2A/2C Receptors Within the Nucleus Accumbens Increases Local Dopaminergic Transmission, Brain Research Bulletin, vol. 51, 2000, No. 1, 75-81. |
Vollenweider, F., et al., A Systems Model of Altered Consciousness: Integrating Natural and Drug-Induced Psychoses, Brain Research Bulletin, vol. 56, No. 5, 2001, 495-507. |
Gao, W., et al., Presynaptic Regulation of Recurrent Excitation by D1 Receptors in Prefontal Circuits, PNAS, Jan. 2001, vol. 98, No. 1, 295-300. |
Meltzer, H., The Role of Serotonin in Antipsychotic Drug ActionNeuropsychopharmacology, vol. 21, No. 2S, 1999, 106S-115S. |
Dowd, C., et al., 1-[4-(3-Phenylalkyl-phenyl]-2-Aminopropanes as 5-HT2A Partial Agonists, J. Med. Chem., 2000, 43, 3074-3084. |
Geyer, M.A., et al., Pharmacological Studies of Prepulse Inhibition Models of Sensorimotor Gating Deficits in Schizophrenia: A Decade in Review, Psychopharmacology, 2001, 156, 2-3, 117-154. |
Braff, D.L, et al., Human Studies of Prepulse Inhibition of Startle: Normal Subjects, Patient Groups, and Pharmacological Studies, Psychopharmacology, 2001, 156, 2-3, 234-258. |
Cilia, J., et al., Long-term Evaluation of Isolation-rearing Induced Prepulse Inhibition Deficits in Rats, Psychopharmacology, 2001, 156, 2-3, 327-337. |
Kaplan & Sadock's Comprehensive Textbook of Psychiatry, Seventh Edition, vol. 1, Lippincott Williams & Wilkins: Philadelphia, 2000, p. 825. |
Koller, W.C., et al., Pharmacologic Treatment of Essential Tremor, American Academy of Neurology, 54, Suppl 4, Jun. 2000, S30-S38. |
PCT International Search Report PCT/US02/06119 dated Jul. 2, 2002. |