Claims
- 1. A compound of the formula ##STR12## and salts thereof, wherein R.sub.1 is mercapto-lower alkylene or lower alkylmercapto-lower alkylene;
- R.sub.2 is hydrogen or lower alkyl;
- R.sub.3 is phenyl-lower alkylene;
- R.sub.4 is hydroxy or lower alkoxy; and
- n is 1 or 2.
- 2. A compound as in claim 1 wherein n is 1.
- 3. A compound as in claim 1 wherein R.sub.1 is mercapto-lower alkylene or lower alkylmercapto-lower alkylene; R.sub.2 is hydrogen or lower alkyl; R.sub.3 is phenyl-lower alkyl; and R.sub.4 is hydroxy.
- 4. A compound as in claim 3 wherein n is 2.
- 5. A compound as in claim 2 wherein R.sub.1 is mercapto-lower alkylene or lower alkylmercapto-lower alkylene; R.sub.2 is hydrogen or methyl; R.sub.3 is phenyl-methyl; and R.sub.4 is hydroxy.
- 6. A compound as in claim 2 wherein R.sub.3 is phenylmethtyl; R.sub.2 is hydrogen or methyl; and R.sub.4 is hydroxy.
- 7. A compound as in claim 6 wherein R.sub.2 is hydrogen.
- 8. A compound as in claim 1 wherein n is 2.
- 9. A composition for relieving angiotension related hypertension is mammalian species comprising about 10 to 500 mg. of a compound of claim 1 and a physiologically acceptable vehicle therefor.
Parent Case Info
This is a division of application Ser. No. 684,605, filed May 10, 1976 now U.S. Pat. No. 4,105,789.
US Referenced Citations (8)
Non-Patent Literature Citations (2)
Entry |
Berse, J. Org. Chem., 27, pp. 3489-3495 (1962). |
Vasilevskii, Zh. Org. Khimii, 2, pp. 244-249 (1970). |
Divisions (1)
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Number |
Date |
Country |
Parent |
684605 |
May 1976 |
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