Weinert, T.A. and L.H. Hartwell, "Cell Cycle Arrest of cdc Mutants and Spficity of the RAD9 Checkpoint," Genetics 134:63-80 (1993). |
Millar, J.B.A. and Russell, P., "The cdc25 M-Phase Inducer: An Unconventional Protein Phosphatase," Cell 68:407-410 (1992). |
Hunter, T. and Pines, J., "Cyclins and Cancer," Cell 66:1071-1074 (1991). |
Koff, A. et al., "Human Cyclin E, a New Cyclin That Interacts with Two Members of the CDC2 Gene Family," Cell 66:1-12 (1991). |
Haas, A.L. et al., "Ubiquitin Conjugation by the Yeast RAD6 and CDC34 Gene Products: Comparison to Their Putative Rabbit Homologs, E2.sub.20k and E2.sub.32K, " The Journal of Biological Chemistry 266(8):5104-5112 (1991). |
Hunt, T., "Destruction's Our Delight," Nature 349:100-101 (1991). |
Glotzer, M. et al., "Cyclin is Degraded by the Ubiquitin Pathway," Nature 349:132-138 (1991). |
Lew, et al., Cell 66:1197-1206 (1991). |
Igarashi, et al., Nature 353:80-83 (1991). |
Weinert, T.A. and Hartwell, L.H., "Characterization of RAD9 of Saccharomyces cerevisiae and Evidence that its Function Acts Posttranslationally in Cell Cycle Arrest after DNA Damage," Molecular and Cellular Biology 10(12):6554-6564 (1990). |
Lock, R.B. and Ross, W.E., "Inhibition of p34.sup.cdc2 Kinase Activity by Etoposide or Irradiation as a Mechanism of G.sub.2 Arrest in Chinese Hamster Ovary Cells.sup.1, " ExpH. and Cell Res. 50:3761-3766 (1990). |
Seufert, W. and Jentsch, S., "Ubiquitin-conjugating enzymes UBC4 and UBC5 mediate selective degradation of short-lived and abnormal proteins," The EMBO Journal 9(2):543-550 (1990). |
Lock, et al., Canc. Res. 50:3767-3771 (1990). |
Hartwell, L.H. and Weinert, T.A., "Checkpoints: Controls That Ensure the Order of Cell Cycle Events," Science 246:629-633 (1989). |
Schiestl, R.H. et al., "Cloning and Sequence Analysis of the Saccharomyces cerevisiae RAD9 Gene and Further Evidence that Its Product Is Required for Cell Cycle Arrest Induced by DNA Damage," Molecular and Cellular Biology 9:1882-1896 (1989). |
Goebl, M.G. et al., "The Yeast Cell Cycle Gene CDC34 Encodes a Ubiquitin-Conjugating Enzyme," Science 241:1331-1335 (1988). |
Weinert, T.A. and Hartwell, L.H., "The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae," Science 241:317-322 (1988). |
Lee, M.G. and Nurse, P., "Complementation used to clone a human homologue of the fission yeast cell cycle gene cdc2," Nature 327:31-35 (1987). |
Pringle, J.R. and Hartwell, L.H., "The Saccharomyces cerevisiae cell cycle," In: The Molecular Biology of the Yeast Saccharomyces: Life cycle and Inheritance (ed. J.N. Strathen et al.), Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, p. 97 (1981). |
Hartwell, L.H., "Three Additional Genes Required for Deoxyribonucleic Acid Synthesis in Saccharomyces cerevisiae," Journal of Bacteriology 115(3):966-974 (1973). |
Zheng, P. et al., "SPK1 Is an Essential S-Phase-Specific Gene of Saccharomyces cerevisiae That Encodes a Nuclear Serine/Threonine/Tyrosine Kinase," Molecular and Cellular Biology 13(9):5829-5842 (1993). |
Weinert, T.A. et al., "Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair," In: Genes & Development, Cold Spring Harbor Laboratory, Cold Sprin Harbor, New York, pp. 1-14 (1994). |
Stern, D.F. et al., "Spkl, a New Kinase from Saccharomyces cerevisiae, Phosphorylates Proteins on Serine, Threonine, and Tyrosine," Molecular and Cellular Biology 11(2):987-1001 (1991). |
Hennessy, K.M. et al., "Subcellular Localization of yeast CDC46 varies with the cell cycle," Genes & Development, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, pp. 2252-2263 (1990). |
Plon, S.E. and Groudine, M., "Defining the human cell checkpoint system," 42nd Annual Meeting of The American Society of Human Genetics, San Francisco, California, Nov. 9-13, 1992. The American J. of Human Genetics 51(4) Abstract No. 259 (1992). |
Plon, S.E. et al., "Complementation of yeast cell-cycle checkpoint mutations by human cDNAS," Abstracts of papers presented at the 1992 Meeting on The Cell Cycle, May 13-17, 1992, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, p. 153 (1992). |
Plon, S.E. et al., "Cloning of the human CDC34 cell cycle gene and a putative human G2 checkpoint gene by complementation in yeast," 43rd Annual Meeting of The American Society of Human Genetics, New Orleans, Louisiana, Oct. 5-9, 1993. The American J. of Human Genetics 53(3) Abstract No. 30 (1993). |
Plon, S.E. et al., "Isolation of human cell cycle genes: CDC34 and a potential G2 checkpoint gene, CCCI," Abstracts of papers presented at the 1994 Meeting on The Cell Cycle, May 18-22, 1994, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, p. 221 (1994). |