CELL SEPARATION IN ELECTROMAGNETIC FIELDS

Information

  • Research Project
  • 3497914
  • ApplicationId
    3497914
  • Core Project Number
    R43GM038413
  • Full Project Number
    1R43GM038413-01
  • Serial Number
    38413
  • FOA Number
  • Sub Project Id
  • Project Start Date
    4/1/1987 - 37 years ago
  • Project End Date
    8/31/1987 - 36 years ago
  • Program Officer Name
  • Budget Start Date
    4/1/1987 - 37 years ago
  • Budget End Date
    8/31/1987 - 36 years ago
  • Fiscal Year
    1987
  • Support Year
    1
  • Suffix
  • Award Notice Date
    3/23/1987 - 37 years ago
Organizations

CELL SEPARATION IN ELECTROMAGNETIC FIELDS

A novel cell separation method utilizing oscillating electromagnetic fields is investigated. The principle of separation lies in the polarizable nature of the live cells in the electric field. In this method, a suspension of heterogeneous cell mixture is subjected to oscillating electric and magnetic fields of the same frequency but oriented perpendicular to each other and 90 degrees out of phase. Theoretical calculation of a model system predicted that unidirectional cell migration occurs. The velocity of migration is determined by the dielectric properties and sizes of the cells. Therefore, by varying the field frequency, cells of different polarization relaxation frequencies and sizes will be sorted into various fractions. The process may be completed within minutes. The achievement of the proposed method will greatly facilitate the inevitable cell sorting procedure needed in clinical and research laboratories and bioengineering operations.

IC Name
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
  • Activity
    R43
  • Administering IC
    GM
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    821
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
    SSS
  • Study Section Name
  • Organization Name
    GENETRONICS, INC.
  • Organization Department
  • Organization DUNS
    122735749
  • Organization City
    SAN DIEGO
  • Organization State
    CA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    921211318
  • Organization District
    UNITED STATES