Claims
- 1. A compound selected from the group consisting of:
- 4-nitrobenzyl 7-[2-(tert-butoxycarbonylmethoxyimino)-2-(2-formamidothiazol-4-yl)acetamido]-3-chloro-3-cephem-4-carboxylate (syn isomer),
- 7-[2-(tert-butoxycarbonylmethoxyimino-2-(2-formamidothiazol-4-yl)-acetamido]-3-chloro-3-cephem-4-carboxylic acid (syn isomer),
- 7-[2-(tert-butoxycarbonylmethoxyimino)-2-(2-aminothiazol-4-yl)-acetamino]-3-chloro-3-cephem-4-carboxylic acid (syn isomer), and
- 7-[2-carboxymethoxyimino-2-(2-aminothiazol-4-yl)acetamido]-3-chloro-3-cephem-4-carboxylic acid (syn isomer).
- 2. A compound of claim 1, which is 7-[2-carboxymethoxyimino-2-(2-aminothiazol-4-yl)acetamido]-3-chloro-3-cephem-4-carboxylic acid (syn isomer).
- 3. A pharmaceutical composition comprising an antimicrobially effective amount of a compound of claim 1 in association with a pharmaceutically acceptable, substantially non-toxic carrier or excipient.
Parent Case Info
This application is a Continuation-In-Part of parent application Ser. No. 886,340, filed Mar. 14, 1978.
US Referenced Citations (2)
Number |
Name |
Date |
Kind |
4166115 |
Takaya et al. |
Aug 1979 |
|
4278793 |
Durckheimer et al. |
Jul 1981 |
|
Foreign Referenced Citations (5)
Number |
Date |
Country |
866038 |
Oct 1978 |
BEX |
2805655 |
Aug 1978 |
DEX |
2810922 |
Sep 1978 |
DEX |
2812625 |
Sep 1978 |
DEX |
2912829 |
Oct 1979 |
DEX |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
886340 |
Mar 1978 |
|