Claims
- 1. A syn compound of the formula: ##STR37## wherein R.sup.2 is hydrogen or aliphatic hydrocarbon which may be substituted with halogen, carboxy or esterified carboxy,
- R.sup.3 and R.sup.4 are each lower alkyl,
- R.sup.5 is carboxy or carboxy modified to a group from which carboxy may be regenerated, and
- R.sup.6 is amino or protected amino, and pharmaceutically acceptable salt thereof.
- 2. The compound of the claim 1, wherein
- R.sup.2 is lower alkyl and
- R.sup.5 is carboxy or esterified carboxy.
- 3. A pharmaceutical antibacterial composition comprising, as an effective ingredient, the compound of claim 1, in association with a pharmaceutically acceptable, substantially nontoxic carrier or excipient.
- 4. A method for treating an infectious disease caused by pathogens, which comprises administering the compound of claim 1 to infected human being or aminals.
- 5. The compound of the claim 4, which is 7-[2-(2-aminothiazol-4-yl)-2-methoxyiminoacetamido]-2,3-dimethyl-3-cephem-4-carboxylic acid (syn isomer).
- 6. The compound of the claim 4, which is 7-[2-(2-trifluoroacetamidothiazol-4-yl)-2-methoxyiminoacetamido]-2,3-dimethyl-3-cephem-4-carboxylic acid (syn isomer).
- 7. The compound of the claim 2, wherein R.sup.6 is amino or halo(lower)alkanamido.
- 8. The compound of claim 1 wherein R.sup.2 is an aliphatic hydrocarbon which may be substituted with carboxy or lower alkoxycarbonyl.
- 9. The compound of claim 1 wherein R.sup.2 is lower alkyl which may be substituted with carboxy or lower alkoxycarbonyl.
Priority Claims (4)
Number |
Date |
Country |
Kind |
10699/77 |
Mar 1977 |
GBX |
|
29245/77 |
Jul 1977 |
GBX |
|
42315/77 |
Oct 1977 |
GBX |
|
75/78 |
Jan 1978 |
GBX |
|
Parent Case Info
This is a division of application Ser. No. 886,340, filed Mar. 14, 1978.
US Referenced Citations (4)
Divisions (1)
|
Number |
Date |
Country |
Parent |
886340 |
Mar 1978 |
|