Claims
- 1. A compound of the formula: ##STR19## or the pharmaceutically acceptable salts thereof wherein: A is arylalkyl, aryl, or heteroaryl optionally substituted with up to 3 groups selected from the group consisting of halogen, trifluoromethyl, hydroxy, straight or branched chain lower alkyl having 1-6 carbon atoms, or straight or branched chain lower alkoxy having 1-6 carbon atoms;
- X is N;
- R.sub.2 is hydrogen, straight or branched chain lower alkyl having 1-6 carbon atoms or phenyl;
- R.sub.3 is hydrogen or straight or branched chain lower alkyl having 1-6 carbon atoms; and
- R.sub.7 is benzyl, phenyl, pyridyl or pyrimidinyl, each of which is unsubstituted or mono or disubstituted with halogen, hydroxy, straight or branched chain lower alkyl having 1-6 carbon atoms, or straight or branched chain lower alkoxy having 1-6 carbon atoms.
- 2. A compound according to claim 1 which is 1-phenyl-4[(4-phenyl-piperazin-1-yl)methyl]imidazole dihydrochloride.
- 3. A compound according to claim 1 which is 1-phenyl-4[(4-phenyl-piperazin-1-yl)methyl]imidazole.
- 4. A compound according to claim 1 which is 1-phenyl-4[(4-(4-fluoropyrimidin-2-yl)piperazin-1-yl)methyl]imidazole dihydrochloride.
- 5. A compound according to claim 1 which is 1-Phenyl-4[(4-(4-fluoropyrimidin-2-yl)piperazin-1-yl)methyl]imidazole.
Parent Case Info
This is a continuation of application Ser. No. 08/459,093, filed Jun. 2, 1995.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
3808212 |
Renth et al. |
Apr 1974 |
|
5478934 |
Yuan et al. |
Dec 1995 |
|
5750700 |
Yuan et al. |
May 1998 |
|
Continuations (1)
|
Number |
Date |
Country |
Parent |
459093 |
Jun 1995 |
|