Claims
- 1. A compound of the formula II ##STR24## in which R.sub.1 and R.sub.2 independently of one another are hydrogen, C.sub.1 -C.sub.8 alkyl or C.sub.3 -C.sub.8 cycloalkyl; C.sub.2 -C.sub.8 alkyl or C.sub.3 -C.sub.8 cycloalkyl, each of which is substituted by halogen; C.sub.1 -C.sub.8 alkyl or C.sub.3 -C.sub.8 cycloalkyl, each of which is substituted by --NR.sub.5 R.sub.6, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkyl--S(O).sub.n --; C.sub.1 -C.sub.4 alkyl or C.sub.3 -C.sub.6 cycloalkyl, each of which is substituted by C.sub.2 -C.sub.4 alkenyl, C.sub.5 -C.sub.6 cycloalkenyl, C.sub.2 -C.sub.6 alkynyl or C.sub.4 -C.sub.8 alkadienyl, wherein the C.sub.2 -C.sub.4 alkenyl, C.sub.5 -C.sub.6 cycloalkenyl or C.sub.4 -C.sub.8 alkadienyl radicals are optionally substituted by halogen; or R.sub.1 and R.sub.2 together are a 4-5-membered C.sub.4 -C.sub.10 alkylene chain which can be interrupted by oxygen, sulfur or N--R.sub.7 ; R.sub.3 is hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkylthio; or C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkylthio which is substituted by halogen; R.sub.5, R.sub.6 and R.sub.7 independently of one another are hydrogen or C.sub.1 -C.sub.4 alkyl, and n is 0, 1 or 2; with the provisos that R.sub.1, R.sub.2 and R.sub.3 are not simultaneously hydrogen and that R.sub.1 and R.sub.2 are not simultaneously hydrogen when R.sub.3 is C.sub.1 -C.sub.4 alkyl.
- 2. A compound of the formula II according to claim 1, in which R.sub.1 and R.sub.2 independently of one another are hydrogen, C.sub.1 -C.sub.8 alkyl or C.sub.3 -C.sub.8 cycloalkyl; C.sub.2 -C.sub.8 alkyl or C.sub.3 -C.sub.8 cycloalkyl which are substituted by halogen; C.sub.1 -C.sub.8 alkyl or C.sub.3 -C.sub.8 cycloalkyl which are substituted by --NR.sub.5 R.sub.6, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkyl--S(O).sub.n --; C.sub.1 -C.sub.4 alkyl or C.sub.3 -C.sub.6 cycloalkyl which are substituted by C.sub.2 -C.sub.4 alkenyl, C.sub.5 -C.sub.6 cycloalkenyl, C.sub.2 -C.sub.6 alkynyl or C.sub.4 -C.sub.8 alkadienyl, wherein the C.sub.2 -C.sub.4 alkenyl, C.sub.5 -C.sub.6 cycloalkenyl or C.sub.4 -C.sub.8 alkadienyl radicals are optionally substituted by halogen; or R.sub.1 and R.sub.2 together are a 4-5-membered C.sub.4 -C.sub.5 alkylene chain which can be interrupted by oxygen, sulfur or N--R.sub.7.
- 3. A compound of the formula II according to claim 1, in which R.sub.1 and R.sub.2 independently of one another are hydrogen, C.sub.1 -C.sub.8 alkyl or C.sub.3 -C.sub.8 cycloalkyl; C.sub.2 -C.sub.8 alkyl or C.sub.3 -C.sub.8 cycloalkyl which are substituted by halogen; C.sub.1 -C.sub.8 alkyl or C.sub.3 -C.sub.8 cycloalkyl which are substituted by --NR.sub.5 R.sub.6, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkyl--S(O).sub.n --; C.sub.1 -C.sub.4 alkyl or C.sub.3 -C.sub.6 cycloalkyl which are substituted by C.sub.2 -C.sub.4 alkenyl, C.sub.5 -C.sub.6 cycloalkenyl, C.sub.2 -C.sub.6 alkynyl or C.sub.4 -C.sub.8 alkadienyl, wherein the C.sub.2 -C.sub.4 alkenyl, C.sub.5 -C.sub.6 cycloalkenyl or C.sub.4 -C.sub.8 alkadienyl radicals are optionally substituted by halogen.
- 4. A compound of the formula II according to claim 1, in which R.sub.1 and R.sub.2 independently of one another are hydrogen, C.sub.1 -C.sub.6 alkyl or C.sub.3 -C.sub.6 cycloalkyl; C.sub.2 -C.sub.6 alkyl or C.sub.3 -C.sub.6 cycloalkyl which are monosubstituted to trisubstituted by halogen; C.sub.1 -C.sub.6 alkyl or C.sub.3 -C.sub.6 cycloalkyl which are substituted by --NR.sub.5 R.sub.6, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkyl--S(O).sub.n --; C.sub.1 -C.sub.4 alkyl or C.sub.3 -C.sub.6 cycloalkyl which are substituted by C.sub.2 -C.sub.4 alkenyl, C.sub.5 -C.sub.6 cycloalkenyl, C.sub.2 -C.sub.4 alkynyl or C.sub.4 -C.sub.8 alkadienyl, wherein the C.sub.2 -C.sub.4 alkenyl, C.sub.5 -C.sub.6 cycloalkenyl or C.sub.4 -C.sub.8 alkadienyl radicals are optionally monosubstituted to trisubstituted by halogen; and R.sub.3 is hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkylthio; or C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkylthio which are monosubstituted to trisubstituted by halogen.
- 5. A compound of the formula II according to claim 1, in which R.sub.3 is in the 6-position of the pyridine ring.
- 6. A compound of the formula II according to claim 1, in which R.sub.3 is hydrogen.
- 7. A compound of the formula II according to claim 1, in which R.sub.2 and R.sub.3 are hydrogen and R.sub.1 is C.sub.1 -C.sub.6 alkyl or C.sub.3 -C.sub.6 cycloalkyl; C.sub.2 -C.sub.6 alkyl or C.sub.3 -C.sub.6 cycloalkyl which are monosubstituted to trisubstituted by halogen; C.sub.1 -C.sub.6 alkyl or C.sub.3 -C.sub.6 cycloalkyl which are substituted by --NR.sub.5 R.sub.6, C.sub.1 -C.sub.4 alkoxy or C.sub.1 -C.sub.4 alkyl--S(O).sub.n --; C.sub.1 -C.sub.4 alkyl or C.sub.3 -C.sub.6 cycloalkyl which are substituted by C.sub.2 -C.sub.4 alkenyl, C.sub.5 -C.sub.6 cycloalkenyl, C.sub.2 -C.sub.4 alkynyl or C.sub.4 -C.sub.8 alkadienyl, wherein the C.sub.2 -C.sub.4 alkenyl, C.sub.5 -C.sub.6 cycloalkenyl or C.sub.4 -C.sub.8 alkadienyl radicals are optionally monosubstituted to trisubstituted by halogen.
- 8. A compound of the formula II according to claim 24, in which R.sub.1 is C.sub.1 -C.sub.6 alkyl, allyl or propargyl, and R.sub.2 is hydrogen, methyl or allyl.
- 9. 3-n-Butylaminopyridin-2-ylsulfonamide according to claim 7.
Priority Claims (1)
Number |
Date |
Country |
Kind |
1826/90 |
May 1990 |
CHX |
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Parent Case Info
This is a Divisional of Ser. No. 07/705,459, filed May 24, 1991 U.S. Pat. No. 5,221,315.
US Referenced Citations (8)
Non-Patent Literature Citations (3)
Entry |
Chemical Abstracts, vol. 102 (No. 7) Abst. No. 102:62050-Z (Feb. 18, 1985). |
J. Pharm. Belg. (1984), vol. 39, (4), pp. 217-224. |
Farmaco Ed., Scient., vol. 12, 392 (1957), pp. 387-393. |
Divisions (1)
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Number |
Date |
Country |
Parent |
705459 |
May 1991 |
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