Claims
- 1. A compound of Formula IIIA:
- 2. A compound according to Formula IIA:
- 3. The compound according to claim 1 or 2, wherein the ribosyl moieties are in the D- configuration.
- 4. The compound according to claim 1 or 2, wherein the ribosyl moieties are in the L- configuration.
- 5. A pharmaceutical composition comprising a compound of Formula IA or IB as described in claim 1 or 2, or a pharmaceutically acceptable salt therof together with a pharmaceutically acceptable carrier therefor.
- 6. A method of treating chronic obstructive pulmonary diseases in a mammal by administering an effective chronic obstructive pulmonary disease treatment amount of a compound of Formula IA or IB as described in claim 1 or 2.
- 7. A method of treating sinusitis, otitis media or nasolacrimal duct obstruction in a mammal by administering an effective mucus secretion clearing amount of a compound of Formula IA or IB as described in claim 1 or 2.
- 8. A method of treating dry eye in a mammal by administering an effective dry eye treatment amount of a compound of Formula IA or IB as described in claim 1 or 2.
- 9. A method of treating retinal detachment in a mammal by administering an effective retinal detachment treatment amount of a compound of Formula I as described in claim 1 or 2.
- 10. A method of facilitating sputum induction in a mammal by administering an amount of a compound of Formula IA or IB as described in claim 1 or 2, effective to facilitate sputum induction.
- 11. A method of facilitating expectoration in a mammal by administering an amount of a compound of Formula IA or IB as described in claim 1 or 2, effective to facilitating expectoration.
Parent Case Info
[0001] This application is a continuation of U.S. application Ser. No. 09/101,395, filed Jul.10, 1998, which was the National Stage of International Application No. PCT/US98/02702, filed Feb., 6, 1998, published Aug. 13, 1998 under PCT Article 21(2) in English; which claims the priority of U.S. application Ser. No. 08/798,508, filed Feb. 10, 1997, now U.S. Pat. No. 5,837,861, and U.S. application Ser. No. 08/797,472, filed Feb. 6, 1997, now U.S. Pat. No. 5,900,407.
Continuations (1)
|
Number |
Date |
Country |
Parent |
09101395 |
Jul 1998 |
US |
Child |
10007451 |
Nov 2001 |
US |