Claims
- 1. A method of contraception whereby at least one steroid hemiacetal of the skeletal formula: ##SPC4##
- (where Y is a ketone oxygen atom or represents a grouping convertible thereto, R.sup.1 is a group COCH.sub.2 X, where X is a hydrogen or halogen atom, and R.sup.2 is a hydrogen atom or an acyloxy group or R.sup.1 is a hydroxy group and R.sup.2 is an aliphatic group which may carry one or more halogen atoms as substituents and where the 6.beta.-, 9.alpha.- and 16-positions carry hydrogen atoms or substituents selected from the group consisting of a halogen atom or an alkyl group at the 6.beta.-position, a halogen atom at the 9.alpha.-position, or a methyl or methylene group, a halogenated methyl or methylene group or a halogen atom at the 16-position) is administered orally to a human subject.
- 2. A method as claimed in claim 1 in which R.sup.2 is a methyl, vinyl or ethynyl groups or a chlorovinyl group.
- 3. A method as claimed in claim 1 in which R.sup.1 is an acetyl group.
- 4. A method as claimed in claim 1 in which Y is ketonic oxygen, R.sup.1 is a hydroxy group and R.sup.2 is an ethynyl group.
- 5. A method as claimed in claim 1 in which the active substance of formula I is administered at a daily dose level of 1 to 25 mg per day.
- 6. A method as claimed in claim 1 in which the active substance of formula I is administered at a daily dose level of 2 to 10 mg per day.
Parent Case Info
This is a continuation of application Ser. No. 190,633, filed 10/19/71, now abandoned, which is in turn a continuation of Ser. No. 14,802, filed 3/2/70, now abandoned, which is in turn a continuation of Ser. No. 747,827, filed 7/26/68, now abandoned, which in turn is a division of Ser. No. 514,691 filed 12/17/65, now abandoned.
Foreign Referenced Citations (1)
Number |
Date |
Country |
941,140 |
Nov 1963 |
UK |
Continuations (1)
|
Number |
Date |
Country |
Parent |
190633 |
Oct 1971 |
|