Guzaev, et al., "A New Approach for Chemical Phosphorylation of Oligonucleotides at the 5'-Terminus," Tetrahedron, vol. 51, No. 34 (1995), pp. 9375-9384. |
Modrich et al., "Deoxyribonucleic Acid Ligase," The Journal of Biological Chemistry, vol. 248, No. 21 (1973), pp. 7502-7511. |
Fritz, "The Oligonucleotide-directed Construction of Mutations in Recombinant Filamentous Phage," Chapter 8, DNA Cloning: A Practical Approach, vol. I, IRL Press, Oxford, 1985, pp. 151-163. |
Barany, "The Ligase Chain Reaction in a PCR World," PCR Methods and Applications, vol. I (1991), pp. 5-16. |
Bannwarth et al. "A New Combined Purification/Phosphorylation Procedure for Oligodeoxynucleotides," Helvetica Chimica Acta, vol., 73 (1990), pp. 1139-1147. |
Gorn et al., "Synthesis of 5'-Phosphorylated Oligodeoxyribonucleotides by Phosphotriester Solid Phase Method in Manual and Automated Variants," Bioorg. Khim. (Moscow), vol. 12, No. 8 (1986), pp. 1054-1063. |
Gaffney et al. "Large-Scale Oligonucleotide Synthesis by the H-Phosphonate Method," Tetrahedron Letters, vol. 29, No. 22 (1988), pp. 2619-2622. |
Marsters et al. "5'-Phosphorylation of Oligonucleotides with Phosphorous Acid in Automated DNA Synthesis," Nucleosides & Nucleotides, vol. 9, No. 8 (1990), pp. 1079-1086. |
Horn et al., "A Chemical 5'-Phosphorylation of Oligodeoxyribonucleotides," DNA, vol. 5, No. 5 (1986), pp. 421-426. |
Wosnick et al., "Rapid Construction of Large Synthetic Genes: Total Chemical Synthesis of Two Different Versions of the Bovine Prochymosin Gene," Gene, vol. 60 (1987), pp. 115-127. |
Robertson et al., "The Use of 5'-Phospho-2 Deoxyribocytidylylriboadenosine as a Facile Route to Chemical Aminoacylation of tRNA," Nucleic Acids Research, vol. 17, No. 23 (1989), pp. 9649-9660. |
Horn et al., "A Chemical 5-Phosphorylation of Oligodeoxyribonucleotides that can be Monitored by Trityl Cation Release," Tetrahedron Letters, vol. 27, No. 39 (1986), pp. 4705-4708. |
Coe et al., "An Improved Method for the Synthesis of Highly Substituted Alkyl Phosphates Including Nucleoside 5'-Phosphates," Chemistry & Industry, No. 21 (1989), pp. 724-725. |
Sekine et al., "A Convenient Method for Removal of the t-Butyl Group from Nucleoside Bis(t-Butyl) Phosphates under Non-acidic Conditions," Tetrahedron Letters, vol. 32, No. 3 (1991), pp. 395-398. |
Uhlmann et al., "Chemical 5'-Phosphorylation of Oligonucleotides Valuable in Automated DNA Synthesis," Tetrahedron Letters, vol. 27, No. 9 (1986), pp. 1023-1026. |
Uhlmann et al., "Automated 5'-Phosphorylation of Oligodeoxyribonucleotides," Chemica Scripta, vol. 26 (1986), pp. 217-219. |
Schwarz et al., "Synthesis of Terminal Nucleoside Phosphates and Thiophosphates via Phosphoramidite Chemistry," Nucleosides & Nucleotides, vol. 6, Nos. 1 and 2 (1987), pp. 537-539. |
Bower et al., "Synthesis and Characterization of Oligodeoxyribonucleotides Containing Terminal Phosphates," Nucleic Acids Research, vol. 15, No. 8 (1987), pp. 3531-3547. |
Connolly et al., "Chemical Synthesis of Oligonucleotides Containing a Free Sulphydryl Group and Subsequent Attachment of Thiol Specific Probes," Nucleic Acids Research, vol. 13, No. 12 (1985), pp. 4485-4502. |
Connolly, "Solid Phase 5'-Phosphorylation of Oligonucleotides," Tetrahedron Letters, vol. 28, No. 4 (1987), pp. 463-466. |
Celebuski et al., "Synthesis and Utility of a DNA Phosphorylating Agent Based on 2-(Triphenylsilyl)ethanol," Journal of Organic Chemistry, vol. 57, No. 20 (1992), pp. 5535-5538. |
Block, Jr., "Diethyl Bis(hydroxymethyl)malonate," Organic Syntheses, vol. 40 (1960), pp. 27-28. |
Nielsen et al., "Improved Synthesis of (Pr.sub.2.sup.i N).sub.2 POCH.sub.2 CH.sub.2 CN," Nucleic Acids Research, vol. 15, No. 8 (1987), p. 3626. |
Hovinen et al., Novel Solid Supports for the Preparation of 3'-Derivatized Oligonucleotides: Introduction of 3'-Alkylphosphate Tether Groups Bearing Amino, Carboxy, Carboxamido, and Mercapto Functionalities, Tetrahedron, vol. 50, No. 24 (1994) pp. 7203-7218. |
Ramalingam et al., "Synthesis of Nitroimidazole Substituted 3,3,9,9-Tetramethyl-4,8-diaza-undecane-2,10-dione Dioximes (Propylene Amine Oximes, PnAOs): Ligands for Technetium-99m Complexes with Potential for Imaging Hypoxic Tissue," Tetrahedron, vol. 51, No. 10 (1995), pp. 2875-2894. |
MacCorquodale et al., "Cycloalkylmethyl Radicals. Part 8. A Conformational Study of Dioxa- and Dithia-cyclohexylmethyl Radicals by EPR Spectroscopy," Journal of the Chemical Society: Perkin Transactions 2, No. 12 (1991), pp. 1893-1899. |
Hughes et al., "Cycloalkylmethyl Radicals. 6. The Unexpectedly High Barrier to the Rotation of Axial CH.sub.2 Groups in Cyclohexylmethyl Radicals," Journal of the American Chemical Society, vol. 110, No. 22 (1988), pp. 7494-7499. |
Bosies et al., "Synthesis of Thioether Phosphocholine Analogues," Lipids, vol. 22, No. 11 (1987), pp. 947-951. |
Teuber et al., "Synthesis and Thermal Stability of 4-Substituted 1,2-Dithiolanes," Acta Chemica Scandinavica, vol. B42 (1988), pp. 629-634. |
March, "Advanced Organic Chemistry-Reactions, Mechanisms, and Structure, "J. Wiley & Sons, N.Y., 3rd Ed., 1985, pp. 689-691 and 829-834. |
Casy et al., "Mechanism of a Mannich Base Exchange Reaction," Journal of the Chemical Society, (1964), pp. 4639-4640. |
Yanagawa et al., "A Convenient Procedure for the Synthesis of Asparagusic Acids," Synthesis, No. 10 (1973), pp. 607-608. |
Cassady et al., "Methyl .alpha.-(Bromomethyl)acrylate," Organic Syntheses, vol. 61 (1983), pp. 77-82. |
Haynes et al., "Preparation of t-Butyl 2-(Phenylthiomethyl)propenoate, t-Butyl 3-(Phenylthio)-2-(phenylthiomethyl)propenoate and Related Compounds," Australian Journal of Chemistry, vol. 37, No. 7, pp. 1571-1578, (1984). |
Singh et al., "Comparisons of Rate Constants for Thiolate-Disulfide Interchange in Water and in Polar Aprotic Solvents Using Dynamic .sup.1H NMR Line Shape Analysis," Journal of the American Chemical Society, vol. 112, No. 3, pp. 1190-1197, 1990. |
Guzaev, et al., "Synthesis of Oligonucleotide Analogs by using Phosphoramidite Reagents Derived from 2,2-bis(hydroxymethyl)malonates," Chemical Abstracts, vol. 125, No. 25 (1996), Abstract No. 125:329248c. |
Tanaka et al., "An Intermediate for the Synthesis of 5'-Phosphorylated Oligodeoxyribonucleotides," Nucleic Acid Chem., Section IV, Nucleotides and Polynucleotides, Wiley, N.Y., 1991, pp. 314-319. |
Conant et al., "Diacetone Alcohol," Organic Synthesis, Collective vol. 1, pp. 199-201, 1941. |