Claims
- 1. A 1,2-dioxetane corresponding to the formula
- 2. A method for generating light which comprises:
(a) providing a stable 1,2-dioxetane of the formula of claim 1. (b) decomposing the stable 1,2-dioxetane with an activating agent to give the corresponding carbonyl compounds
- 3. The method of claim 2 wherein the dioxetane corresponds to the formula:
- 4. The method of claim 3 wherein the dioxetane is of the formula:
- 5. The method of claim 3 wherein the dioxetane is of the formula:
- 6. The method of claim 3 wherein the dioxetane is of the formula:
- 7. The method of claim 3 wherein the dioxetane is of the formula:
- 8. The 1,2-dioxetane of claim 1 which is any of:
[(4-methoxy)-4-(3-phosphoryloxyphenyl)] spiro [1,2-dioxetane-3,13′-(8-n-propyl) tricyclo[7.3.1.02,7] tridec-2,7-ene], disodium salt; [(4-Methoxy)-4-(3-phosphoryloxyphenyl)] spiro [1,2-dioxetane-3,13′-tricyclo [7.3.1,02,7] tridec-2,7-ene], disodium salt; [(4-methoxy)-4-(3-phosphoryloxyphenyl] spiro [1,2-dioxetane-3,2′-adamantan-4,5-ene], disodium salt; [4-(2,2,2-trifluoroethoxy)-4-(3-phosphoryloxyphenyl)] spiro [1,2-dioxetane-3,13′-tricyclo[7.3.1.02,7]tridec-2,7-ene], disodium salt; [4-(2-phenoxyethoxyl)-4-(3-phosphoryloxyphenyl) spiro [1,2-dioxetane-3,2′-adamantane], disodium salt; [4-(2-phenoxyethoxyl)-4-(3-phosphoryloxyphenyl)spiro [1,2-dioxetane-3 13′-tricyclo[7.3.1.02,7]tridec-2,7-ene], disodium salt; [4-(2-phenoxyethoxyl)-4-(3-phosphoryloxyphenyl) spiro [1,2-dioxetane-3,2′-5-chloro-adamantane], disodium salt; [(4-Methoxy)-4-(3-phosphoryloxy-4-chlorophenyl)] spiro [1,2-dioxetane-3,13′-tricyclo [7.3.1,02,7] tridec-2,7-ene], disodium salt; [(4-Methoxy)-4-(3-phosphoryloxyphenyl)] spiro [1,2-dioxetane-3,9′-(2,4-diphenylbicyclo[3.3.1]non-2-ene)], disodium salt;
- 9. An alkene intermediate for the formation of a stable 1,2-dioxetane corresponding to the formula of claim 2:
- 10. The method of claim 3 wherein the activating agent is an enzyme from a biological source.
CROSS REFERENCE TO RELATED APPLICATION
[0001] This application is a national application based on PCT Application, Serial No. 99/20590, filed Sep. 8, 1999, which is a completion application of U.S. provisional patent application Serial No. 6-0/099693, filed Sep. 8, 1998 for “Chemiluminescent 1,2 dioxetanes”, the disclosures of which are hereby incorporated by reference.
Divisions (1)
|
Number |
Date |
Country |
Parent |
09643063 |
Aug 2000 |
US |
Child |
10313109 |
Oct 2002 |
US |