Schwartz et al. Potentiation of apoptosis by flavopiridol in mitomycin-C-treated gastric and breast cancer cells. Clinical Cancer Res. 3 (1997): 1467-1472.* |
Schwartz et al, J. Natl Cancer Inst. vol. 87 No. 18, Sep. 20, 1995.* |
Akinaga et al, Cancer Chemother. Pharmacol., vol. 32: 183-189, 1993.* |
Sachs et al., J. Biol. Chem. vol. 270 (44) p. 26639-26648, Nov. 3, 1995.* |
Kedderis et al., Fundamental & Applied Toxicology 25, 201-217, 1995.* |
Birchall et al., J. Pharm. and Exp. Therapeutics, vol. 268 No. 2, p. 922-929, 1994.* |
Kraft et al., Proc. Natl. Acad. Sci. vol. 83 p. 1334-1338, Mar. 1986.* |
S. Grant, et al., Exp. Cell Res. 7:69-76. (Exhibit 1). |
Akinga et al., (1993) Enhancement of Antitumor Activity of Mitomycin C In Vitro and In Vivo by UCN-01, a Selective Inhibitor of Protein Kinase C, Cancer Chemother. Pharmacol., vol. 32, No. 3:183-189. |
Foti et al., (1993) Proceedings of the American Association for Cancer Research, American Association for Cancer Research, vol. 34: 410-411. |
Foti et al., (1995) Proceedings of the American Association for Cancer Research, American Association for Cancer Research, vol. 36:11. |
Haimovitz-Friedman et al., (1994) Protein Kinase C Mediates Basic Fibroblast Growth Factor Protection of Endothelial Cells against Radiation-induced Apoptosis, Cancer Research, vol. 54: 2591-2597. |
Hofmann et al., (1988) Enhancement of the Antiproliferative Effect of Cis-Diamminedichloroplatinum(II) and Nitrogen Mustard by Inhibitors of Protein Kinase C, Int. J. Cancer, vol. 42: 382-388. |
Jarvis et al., (1994) Effects of Bryostatin 1 and other Pharmacological Activators of Protein Kinase C on 1-[β-D-Arabino-furanosyl]Cytosine-induced Apoptosis in HL-60 Human Promyelocytic Leukemia Cells, Biochemical Pharmacology, vol. 47, No. 5: 839-852. |
Lane et al., (1993) A Death in the Life of p53, Nature, vol. 362: 786-787. |
Mohammad et al., (1994) Successful Treatment of Human Walden-strom's Macroglobulinemia with Combination Biological and Chemo-therapy Agents, Cancer Research, vol. 54: 165-168. |
Mohammad et al., (1995) Bryostatin 1 induces Apoptosis and Aug-ments Inhibitory Effects of Vincristine in Human Diffuse Large Cell Lymphoma, Leukemia Research, vol. 19, No. 9: 667-673. |
Ponnathpur et al., (1995) Effects of Modulators of Protein Kinases on Taxol-induced Apoptosis of Human Leukemic Cells Possessing Dis-parate Levels of p26BCL-2 Protein, Clinical Cancer Research, vol. 1: 1399-1406. |
Robinson et al., (1994) Potentiation of the Antitumor Activity of Doxorubicin by the Protein Kinase C Inhibitor Safingol., Proc. Annu. Meet. Am., Assoc., Cancer Res., vol. 35: A266. |
Schwartz et al., (1991) Protein Kinase C Activity and Multidrug Resistance in MOLT-3 Human Lymphoblastic Leukemia Cells Resistant to Timetrexate, Cancer Research, vol. 51: 55-61. |
Schwartz G.K., (1996) Protein Kinase C Inhibitors as Inducers of Apoptosis for Cancer Therapy, Exp. Opin. Invest. Drugs, vol. 5, No. 12: 1601-1615. |
Schwartz et al., (1995) Potentiation of Apoptosis by Treatment with Protein Kinase C-Specific Inhibitor Safingol in Mitomycin C-Treated Gastric Cancer Cells, Journal of the National Cancer Institute, vol. 87: 1394-1399. |
Wang et al., (1995) Apoptosis in 7-Hydroxystauropurine-treated T Lymphoblasts Correlates with Activitation of Cyclindependent Kinases 1 and 2, Cell Growth and Differentiation, vol. 6: 927-936. |