Claims
- 1. A complex of human growth hormone and zinc, comprising human growth hormone and zinc at a molar ratio of about 1:1.6 to about 1:2.4.
- 2. A complex of claim 1, wherein the complex has a mean particle diameter of less than 10 μm.
- 3. A method for producing a complex of human growth hormone and zinc according to claim 1, which comprises mixing human growth hormone and zinc in the form of a zinc salt at a molar ratio of about 1:1.6 to about 1:2.4, for a time and under conditions to produce the complex.
- 4. A method for producing a micronized human growth hormone complex, which comprises atomizing a complex of human growth hormone and zinc, said complex comprising human growth hormone and zinc at a molar ratio of about 1:1.6 to about 1:2.4, thereby to produce the micronized human growth hormone complex.
- 5. A pharmaceutical composition which comprises a complex of claim 1 in admixture with a pharmaceutically acceptable carrier or diluent.
- 6. A pharmaceutical composition for treating pituitary dwarfism, which comprises an effective amount of the complex of claim 1 in admixture with a pharmaceutically acceptable carrier or diluent.
- 7. A method according to claim 3, wherein the zinc salt is a water-soluble zinc salt.
Priority Claims (1)
Number |
Date |
Country |
Kind |
9-261251 |
Sep 1997 |
JP |
|
Parent Case Info
This application is a division of Ser. No. 09/151,783, filed Sep. 11, 1998 now U.S. Pat. No. 6,191,107, which claims the benefit of foreign priority under 35 U.S.C.§119(a)-(d) from Japan Application No. 261251/1997, filed Sep. 26,1997.
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