Patent Application
20250163345
The invention relates to compositions comprising at least one biosurfactant and at least one persicomycin.
Persicomycins are 3-(3′-hydroxy)hydroxy fatty acids and represent a family among the phytobacterial toxins. They are associated with necrosis in peach trees, with 3-(3′-hydroxydecanoyloxy)hexadecenoic acid being the most prominent persicomycin, see Eur J Biochem. 1996 Aug. 1; 239(3):702-9.
EP2797571 discloses compositions comprising water, at least one biosurfactant and at least one fatty acid, wherein the fraction of the sum of all surfactants in the composition is from 1 to 30% by weight, and that the fraction of fatty acid, based on the sum of fatty acid and surfactants, is from 0.1 to 20% by weight.
It is an object of the intent invention to provide compositions with outstanding cleaning capabilities, especially in household care applications.
It was found that, surprisingly, compositions comprising at least one biosurfactant and at least one persicomycin have special properties well suited for cleaning applications.
The present invention therefore provides a composition comprising
The invention further provides a method of cleaning articles as described in more detail in claim 9.
One advantage of the present invention is that the compositions of the instant invention have a very good cleaning performance, especially in fatty stain removal from fabrics.
Another advantage of the present invention is that the compositions of the instant invention can be rinsed off from a surface, preferably from fibres, that had been cleaned, very easily.
A further advantage is that the compositions of the instant invention support enzyme stability in terms of storage.
One advantage of the present invention is that a pure biological detergent is provided with all ingredients being of biological origin by the composition of the instant invention.
Another advantage of the present invention is that detergents with less total surfactant load while maintaining cleaning capabilities are provided by the composition of the instant invention.
Another advantage of the present invention is that a detergent with increases performance, especially on fatty stains.
A further advantage is by the composition of the instant invention a high-performance detergent is provided, which uses less ingredients. Thereby, the formulation complexity is reduced greatly, resulting in a simpler production process.
Another advantage of the present invention is that the formula shows especially good emulsification and dispersing properties.
Another advantage of the present invention is that detergents using mild surfactants with low aqua toxicity are provided by the composition of the instant invention.
Another advantage of the present invention is that the compositions of the instant invention can be formulated as 100% biodegradable.
Another advantage is that the formulation shows excellent compatibility with all materials contained in washing machines with respect to corrosion.
Another advantage is that the formulation can be diluted very easily with water without the necessity of excessive stirring.
One advantage of the present invention is that the compositions according to the instant invention have a positive odour profile.
Another advantage of the present invention is that the compositions according to the instant invention have an improved colour stability. Colour change reactions could come from Maillard reaction, which is a chemical reaction between proteins or amino acids and sugars. Both reaction partners, proteins and sugars, are typically contained in small amounts in a fermentative produced biosurfactant like Rhamnolipids, Sophorolipids or Rubiwettin. These small concentrations are sufficient to have a colour change from light to dark.
A further advantage is that the compositions according to the instant invention have improved cleaning properties of surfaces.
Another advantage is that the compositions according to the instant invention has excellent foaming properties.
A further advantage is that the compositions according to the instant invention is their reduced irritation for human skin.
Another advantage is that the compositions according to the instant invention is their mildness and good physiological compatibility, in particular characterized by a high value in the red blood cell (RBC) test.
A further advantage is that the compositions according to the instant invention is their good skin feel during and after washing.
Another advantage is that the compositions according to the instant invention is that they leave behind a smooth and soft skin feel after washing.
Another advantage is that the compositions according to the instant invention is their outstanding microbial stability.
Another advantage is that the compositions according to the instant invention have an improved ability to dissolve oils and fats.
Another advantage is that that the composition according to the instant invention has a higher viscosity than the corresponding composition without persicomycin.
The present invention provides a composition comprising
Within the context of the present invention, “biosurfactants” are understood as meaning all glycolipids produced by fermentation. The term “biosurfactant” also covers glycolipids that are chemically or enzymatically modified after fermentation, as long as structurally a glycolipid remains. Raw materials for producing the biosurfactants that can be used are carbohydrates, in particular sugars such as e.g. glucose and/or lipophilic carbon sources such as fats, oils, partial glycerides, fatty acids, fatty alcohols, long-chain saturated or unsaturated hydrocarbons.
In the context of the present invention, the terms “surfactant” is understood to mean organic substances having interface-active properties that have the ability to reduce the surface tension of water at 20° C. and at a concentration of 0.5% by weight based on the overall composition to below 45 mN/m. Surface tension is determined by the Du Nouy ring method at 20° C.
Within the context of the present invention “persicomycins” are understood as meaning 3-(3′-hydroxy)hydroxy fatty acids as well as the corresponding salts thereof.
Where average values are stated hereinbelow, then, unless stated otherwise, these are number-averaged average values.
Unless stated otherwise, percentages are data in percent by weight.
Wherever measurement values are stated hereinbelow, then, unless stated otherwise, these have been determined at a temperature of 25° C. and a pressure of 1013 mbar.
The composition according to the instant invention preferably comprises as component A) at least one biosurfactant selected from rhamnolipids, sophorolipids, glucolipids, cellulose lipids, mannosylerythritol lipids and trehalose lipids, preferably rhamnolipids, sophorolipids and glucolipids, most preferably rhamnolipids. The biosurfactants can be produced e.g. as in EP 0 499 434, U.S. Pat. No. 7,985,722, WO 03/006146, JP 60 183032, DE 19648439, DE 19600743, JP 01 304034, CN 1337439, JP 2006 274233, KR 2004033376, JP 2006 083238, JP 2006 070231, WO 03/002700, FR 2740779, DE 2939519, U.S. Pat. No. 7,556,654, FR 2855752, EP 1445302, JP 2008 062179 and JP 2007 181789 or the documents cited therein. Suitable biosurfactants can be acquired e.g. from Soliance, France.
Preferably, the composition according to the instant invention has, as biosurfactant at least one selected from rhamnolipids, in particular mono-, di- or polyrhamnolipids, glucolipids, in particular mono-, di- or polyglucolipids, and sophorolipids, in particular mono-, di- or polysophorolipids, preferably selected from rhamnolipids and glucolipids, most preferably rhamnolipids.
The term “rhamnolipids” in the context of the present invention preferably is understood to mean particularly compounds of the general formula (I) and salts thereof,
where
The term “di-rhamnolipid” in the context of the present invention is understood to mean compounds of the general formula (I) or salts thereof, where nRL=1.
The term “mono-rhamnolipid” in the context of the present invention is understood to mean compounds of the general formula (I) or salts thereof, where nRL=0.
Distinct rhamnolipids are abbreviated according to the following nomenclature:
The nomenclature used therefore does not distinguish between “CXCY” and “CYCX”.
For rhamnolipids where mRL=0, monoRL-CX or diRL-CX is used accordingly.
If one of the abovementioned indices X and/or Y is provided with “:Z”, this signifies that the respective residue R1RL and/or R2RL is equal to an unbranched, unsubstituted hydrocarbon residue having X-3 or Y-3 carbon atoms having Z double bonds.
Methods for preparing the relevant rhamnolipids are disclosed, for example, in EP2786743 and EP2787065.
Rhamnolipids applicable in the context of the instant invention can also be produced by fermentation of Pseudomonas, especially Pseudomonas aeruginosa, which are preferably non genetically modified cells, a technology already disclosed in the eighties, as documented e.g. in EP0282942 and DE4127908. Rhamnolipids produced in Pseudomonas aeruginosa cells which have been improved for higher rhamnolipid titres by genetical modification can also be used in the context of the instant invention; such cells have for example been disclosed by Lei et al. in Biotechnol Lett. 2020 June; 42(6):997-1002.
Rhamnolipids produced by Pseudomonas aeruginosa are commercially available from Jeneil Biotech Inc., e.g. under the tradename Zonix, from Logos Technologies (technology acquired by Stepan), e.g. under the tradename NatSurFact, from Biotensidion GmbH, e.g. under the tradename Rhapynal, from AGAE technologies, e.g. under the name R90, R95, R95Md, R95Dd, from Locus Bio-Energy Solutions and from Shanghai Yusheng Industry Co. Ltd., e.g. under the tradename Bio-201 Glycolipids.
The present invention provides a composition preferably comprising as biosurfactant rhamnolipids, characterized in that the biosurfactant component A) comprises
This surprisingly elevates the viscosity of the composition according to the instant invention. Preferably this preferred embodiment is combined with a content of soil release agents (see below), preferably of the carboxy methyl inulin type.
The present invention further provides a composition preferably comprising as biosurfactant rhamnolipids, characterized in that the biosurfactant component A) comprises
A preferred composition according to the invention is characterized in that the composition comprises as biosurfactant rhamnolipids as described above with a content of
A further preferred composition according to the invention is characterized in that the composition comprises as biosurfactant rhamnolipids as described above with a content of
A further preferred composition according to the invention is characterized in that the composition comprises as biosurfactant rhamnolipids as described above with a content of
An even further preferred composition according to the invention is characterized in that the composition comprises as biosurfactant rhamnolipids as described above with a content of
The present invention provides a composition alternatively preferably comprising as biosurfactant rhamnolipids, characterized in that the biosurfactant component A) comprises
The alternatively preferred composition according to the invention is preferably characterized in that the composition comprises as biosurfactant rhamnolipids as described above with a content of
The alternatively preferred composition according to the invention is preferably characterized in that the composition comprises as biosurfactant rhamnolipids as described above with a content of
The alternatively preferred composition according to the invention is preferably characterized in that the composition comprises as biosurfactant rhamnolipids as described above with a content of
The alternatively preferred composition according to the invention is preferably characterized in that the composition comprises as biosurfactant rhamnolipids as described above with a content of
Methods for preparing the relevant rhamnolipids are disclosed, for example, in EP2786743 and EP2787065.
Rhamnolipids applicable in the context of the instant invention can also be produced by fermentation of Pseudomonas, especially Pseudomonas aeruginosa, which are preferably non genetically modified cells, a technology already disclosed in the eighties, as documented e.g. in EP0282942 and DE4127908. Rhamnolipids produced in Pseudomonas aeruginosa cells which have been improved for higher rhamnolipid titres by genetical modification can also be used in the context of the instant invention; such cells have for example been disclosed by Lei et al. in Biotechnol Lett. 2020 June; 42(6):997-1002.
Rhamnolipids produced by Pseudomonas aeruginosa are commercially available from Jeneil Biotech Inc., e.g. under the tradename Zonix, from Logos Technologies (technology acquired by Stepan), e.g. under the tradename NatSurFact, from Biotensidion GmbH, e.g. under the tradename Rhapynal, from AGAE technologies, e.g. under the name R90, R95, R95Md, R95Dd, from Locus Bio-Energy Solutions and from Shanghai Yusheng Industry Co. Ltd., e.g. under the tradename Bio-201 Glycolipids.
In the context of the present invention, the term “sophorolipids” preferably is understood as meaning compounds of the general formulae (IIa) and (IIb) and salts thereof
where
Sophorolipids may be used in accordance with the invention in their acid form or their lactone form. Preferred compositions according to the instant invention comprise a sophorolipid in which the ratio by weight of lactone form to acid form is in the range of 20:80 to 80:20, especially preferably in the ranges of 30:70 to 40:60.
To determine the content of sophorolipids in the acid or lactone form in a formulation, refer to EP1411111B1, page 8, paragraph [0053].
In connection with the present invention, the term “glucolipids” preferably is understood as meaning compounds of the general formula (III) and salts thereof,
where
Distinct glucolipids are abbreviated according to the following nomenclature:
“GL-CXCY” is understood as meaning glucolipids of the general formula (III) in which one of the radicals R1GL and R2GL=(CH2)o—CH3 where o=X-4 and the remaining radical R1GL or R2GL=(CH2)o—CH3 where o=Y-4.
The nomenclature used thus does not differentiate between “CXCY” and “CYCX”.
If one of the aforementioned indices X and/or Y is provided with “:Z”, then this means that the respective radical R1GL and/or R2GL=an unbranched, unsubstituted hydrocarbon radical with X-3 or Y-3 carbon atoms having Z double bonds.
Methods for production of glucolipids can be carried out as described in WO2019154970.
A preferred composition according to the instant invention is characterized in that the ratio of component B) to component A) is in the range of 1:2000 to 1:3, preferably 1:1000 to 1:10, more preferably 1:300 to 1:20, most preferably 1:100 to 1:25.
When determining the content of component A) and B) in the context of the present invention, the mass of the non-salt form is taken into account; thus, the weight of the corresponding cation is disregarded.
A preferred composition according to the instant invention further comprises
Enzymes are useful additives in laundry compositions. The enzymes preferably comprised in the composition according to the instant invention are selected from the group consisting of protease, amylase, lipase, pectinase, cellulase, phosphodiesterase, mannanase, cutinase, pectate lyase, peroxidase, oxidase and laccase with protease, amylase, lipase, pectinase, cellulase, phosphodiesterase and mannanase being especially preferred.
The enzymes to be used in the context of the present invention can, for example, originally originate from microorganisms, for example of the genera Bacillus, Streptomyces, Humicola, or Pseudomonas, and/or be produced by suitable microorganisms according to known biotechnological processes, for example by transgenic expression hosts, for example of the genera Escherichia, Bacillus, or filamentous fungi.
It is emphasized that it can in particular also be technical enzyme preparations of the respective enzyme, i.e. accompanying substances may be present. The enzymes can therefore be packaged and used together with accompanying substances, for example from fermentation or with other stabilizers.
Suitable proteases include those of bacterial, fungal, plant, viral or animal origin e.g. vegetable or microbial origin. Microbial origin is preferred. Chemically modified or protein engineered mutants are included. It may be an alkaline protease, such as a serine protease or a metalloprotease. A serine protease may for example be of the S1 family, such as trypsin, or the S8 family such as subtilisin. A metalloproteases protease may for example be a thermolysin from e.g. family M4 or other metalloprotease such as those from M5, M7 or M8 families.
Examples of proteases are the subtilisins BPN from Bacillus amyloliquefaciens and Carlsberg from Bacillus licheniformis, the protease PB92, the subtilisins 147 and 309, the protease from Bacillus lentus, subtilisin DY and the subtilases, but no longer assigned to the subtilisins in the narrower sense Thermitase, Proteinase K and the proteases TW3 and TW7.
Subtilisin Carlsberg is in a further developed form under the trade name Alcalase® from the Novozymes A/S, Bagsvasrd, Denmark.
The subtilisins 147 and 309 are sold by the Novozymes company under the trade names Esperase® and Savinase®, respectively. The protease variants under the name BLAP® are derived from the protease from Bacillus lentus DSM 5483. Further usable proteases are, for example, those under the trade names Durazym®, Relase®, Everlase®, Nafizym®, Natalase®, Kannase® and Ovozyme® from Novozymes, which are among trade names, Purafect®, Purafect® OxP, Purafect® Prime, Excellase® and Properase® from the company Danisco/Genencor, which operates under the trade name Protosol® from Company Advanced Biochemicals Ltd., Thane, India, which operates under the trade name Wuxi® from the company Wuxi Snyder Bioproducts Ltd., China, which operates under the trade name Proleather® and Protease P® from Amano Pharmaceuticals Ltd., Nagoya, Japan, and the enzyme available under the name Proteinase K-16 from Kao Corp., Tokyo, Japan.
The proteases from Bacillus gibsonii and Bacillus pumilus, which are disclosed in the international patent applications WO 08/086916 and WO 07/131656, are also particularly preferably used. Further advantageously usable proteases are disclosed in the patent applications WO 91/02792, WO 08/007319, WO 93/18140, WO 01/44452, GB 1243784, WO 96/34946, WO 02/029024 and WO 03/057246. Other proteases that can be used are those found in the microorganisms Stenotrophomonas maltophilia, in particular Stenotrophomonas maltophilia K279a, Bacillus intermedius and Bacillus sphaericus are naturally present.
Other commercially available proteases are: Liquanase® EC 3.5 L, Liquanase® Evity® EC 3.5 L, Liquanase® 3.5 L, Liquanase® Evity® 3.5 L, Preferenz P100, Preferenz P200, Preferenz P300, Biotouch ROC, BIOPROTEASA L 800 ST, Bioproteasa 800 P, Bioproteasa L 800, Lavergy® Pro 114 LS, Progress Uno EC 100 L, Progress Uno 100 L, Progress Uno 101 L, EFFECTENZ™ P 100 (A01339), EFFECTENZ™ P 150, Savinase® Evity® EC 16 L, Savinase® Evity® EC 24 T, Savinase® Evity® 16 L, Savinase® Evity® 24 T, Excellenz P 1250, Blaze® Evity® EC 150 T, Blaze® Evity® 150 T, Blaze® Evity® 125 T, Blaze Evity 16 L, Excellase, Purafect, Purafect OxP, Purafect Prime, Properase, Blaze® Pro EC 100 L, Blaze® Pro 100 L, Blaze Exceed 100 T, Progress Key 150 T, Progress Excel 101 L.
A protease preferably comprised in the composition according to the instant invention is Liquanase® 2.5 L.
Suitable amylases which can be used herein may be an alpha-amylase or a glucoamylase and may be of bacterial or fungal origin. Chemically modified or protein engineered mutants are included. Amylases include, for example, alpha-amylases obtained from Bacillus, e.g., a special strain of Bacillus licheniformis, described in more detail in GB 1,296,839.
Examples of amylases are the α-amylases from Bacillus licheniformis, from Bacillus amyloliquefaciens or from Bacillus stearothermophilus and, in particular, their improved further developments for use in detergents or cleaning agents.
The enzyme from Bacillus licheniformis is available from the Novozymes company under the name Termamyl® and from the Danisco/Genencor company under the name Purastar® ST.
Further development products of this α-amylase are available from Novozymes under the trade names Duramyl® and Termamyl® ultra, from Danisco/Genencor under the name Purastar® OxAm and from Daiwa Seiko Inc., Tokyo, Japan, as Keistase®.
The α-amylase from Bacillus amyloliquefaciens is sold by the Novozymes company under the name BAN®, and variants derived from the α-amylase from Bacillus stearothermophilus under the names BSG® and Novamyl®, also from the Novozymes company.
Furthermore, the α-amylase from Bacillus sp.
A 7-7 (DSM 12368) and the cyclodextrin glucanotransferase (CGTase) from Bacillus agaradherens (DSM 9948) should be emphasized.
The amylolytic enzymes disclosed in the international patent applications WO 03/002711, WO 03/054177 and WO07/079938 can also be used.
Fusion products of all the molecules mentioned can also be used. In addition, the further developments of the α-amylase from Aspergillus niger and A. oryzae available from the Novozymes company under the trade names Fungamyl® are suitable. Further commercial products that can be used advantageously are, for example, the Amylase-LT® and Stainzyme® or Stainzyme Ultra® or Stainzyme Plus®, the latter also from Novozymes. Variants of these enzymes obtainable by point mutations can also be used according to the invention.
Other commercially available amylases are: Amplify Prime EC 110 L, Amplify Prime 100 L, PREFERENZ S 110, Bioamyl P, Stainzyme Plus Evity, Stainzyme® Plus Evity® EC 12 T, Stainzyme® Plus Evity® EC 24 T, Stainzyme® Plus Evity® 24 T, EFFECTENZ™ S 100, EFFECTENZ™ S210, Bialfa T, Achieve Alpha EC 110 L, Achieve Alpha 100 L, Achieve® Advance 150 T, Stainzyme, Amplify, Duramyl, Novamyl, Amplify™ Prime 100 L is preferably comprised in the composition according to the instant invention
Suitable cellulases include those of bacterial or fungal origin. Chemically modified or protein engineered mutants are included. Suitable cellulases include cellulases from the genera Bacillus, Pseudomonas, Humicola, Fusarium, Thielavia, Acremonium, e.g., the fungal cellulases produced from Humicola insolens, Myceliophthora thermophila and Fusarium oxysporum disclosed in U.S. Pat. Nos. 4,435,307, 5,648,263, 5,691,178, 5,776,757 and WO 89/09259.
Examples of cellulases (endoglucanases, EG) is the fungal, endoglucanase (EG)-rich cellulase preparation or its further developments, which is offered by the Novozymes company under the trade name Celluzyme®.
The products Endolase® and Carezyme®, also available from Novozymes, are based on the 50 kD-EG, or the 43 kD-EG from Humicola insolens DSM 1800. Other commercial products from this company that can be used are Cellusoft®, Renozyme® and Celluclean®. Cellulases, for example, which are available from the company AB Enzymes, Finland, under the trade names Ecostone® and Biotouch®, and which are at least partly based on the 20 kD EG from Melanocarpus, can also be used. Other cellulases from AB Enzymes are Econase® and Ecopulp®. Further suitable cellulases are from Bacillus sp. CBS 670.93 and CBS 669.93, the ones from Bacillus sp. CBS 670.93 from the company Danisco/Genencor is available under the trade name Puradax®. Other commercial products from Danisco/Genencor that can be used are “Genencor detergent cellulase L” and IndiAge® Neutra.
Other commercially available cellulases are: Carezyme® Premium EC 4510 L, Carezyme® Premium Evity® EC 5000 T, Carezyme® Premium 4500 L, Carezyme® Premium Evity® 5000 T, REVILATENZ 200, Biotouch DCL/FCL, Biosoft L Pure, Rocksoft, Retrocell, Retrocell ZircoN, Puradax EG 7000L, Biotouch FCC, BIOCELULASA MC L, BIOCELULASA MC P, Celluclean® EC 5000 L, Celluclean® 5000 L, REVILATENZ 200, Biotouch FLX, Lavergy® C Bright 100 L, Celluclean® Evity® EC 4500 T, Celluclean® Evity® 4500 T, Biotouch DCC,
Further preferred enzymes present in the composition of the instant invention are those known under the term glycosidases (E.C. 3.2.1.X). These include in particular arabinases, fucosidases, Galactosidases, galactanases, arabico-galactan-galactosidases, mannanases (also referred to as mannosidases or mannases), glucuronosidases, agarase, carrageenases, pullulanases, β-glucosidases, xyloglucanases (xylanases), xanthanases and pectin-degrading enzymes. Preferred glycosidases are also summarized under the term hemicellulases. Hemicellulases include in particular mannanases, xyloglucanases (xylanases), β-glucosidases and carrageenases and also pectinases, pullulanases and β-glucanases. Pectinases are pectin-degrading enzymes, the hydrolytic pectin-degrading enzymes in particular belonging to the enzyme classes EC 3.1.1.1 1, EC 3.2.1.15, EC 3.2.1.67 and EC 3.2.1.82. In the context of the present invention, the pectinases also include enzymes with the designations pectin lyase, pectin esterase, pectin demethoxylase, pectin methoxylase, pectin methylesterase, pectase, pectin methylesterase, pectinoesterase, pectin-galle-lactase, pectin-gal-galase, pectin-gal-galase, pectin-gal-galase, pectin-gal-galase, pectin-gal-galase, pectin-gal-galase, pectin-gal-galonase, pectin-galactolase, endopoly-nolase, pectin-poly-galase, pectin-polyhydrolase, pectin-poly-galase, pectin-polyhydrolase, pectin-poly-galase, pectin-poly-galase-a-1, 4-galacturonide glycanohydrolase, endogalacturonase, endo-D-galacturonase, galacturan 1, 4-a-galacturonidase, exopolygalacturonase, poly (galacturonate) hydrolase, exo-D-galacturonase, exo-D-galacturonanase-Galacturonase, exo-poly-a-galacturonosidase, Exopolygalacturonosidase or exopolygalacturanosidase.
Examples of enzymes suitable in this regard are, for example, under the names Gamanase®, Pektinex AR® or Pectaway® from Novozymes, under the name Rohapec® B1 L from AB Enzymes and under the name Pyrolase® from Diversa Corp., San Diego, CA, USA.
The β-glucanase obtained from Bacillus subtilis is available under the name Cereflo® from the Novozymes company.
Glycosidases or hemicellulases which are particularly preferred according to the invention are mannanases, which for example, under the trade name Mannaway® by the Novozymes company or Purabrite® by the Danisco/Genencor company.
Examples of commercially available mannanases are: Mannaway® EC 200 L, Mannaway® EC 108 L, Mannaway® 200 L, Mannaway® 100 L, PREFERENZ M100, Biotouch M, Biomananasa 2XL. A mannanase preferably comprised in the composition according to the instant invention is Mannaway® 4.0 L.
Examples of commercially available pectate lyases are: Xpect® EC 1000 L, Xpect® EC 1000 T, Xpect® 1000 L, Xpect® 1000 T, PREVERENZ F 1000, Pectex Pure, Lavergy® Pro 106 L, Lavergy® Pro 106 LS.
Examples of commercially available licheninases are: Lift INTENT 100 L, Lift INTENT 100 T.
Suitable lipases and cutinases include those of bacterial or fungal origin. Chemically modified or protein engineered mutant enzymes are included. Examples of lipases or cutinases are those originally from Humicola lanuginose (Thermomyces lanuginosus) obtainable or further developed therefrom, in particular those with the amino acid substitution D96L. They are sold, for example, by the company Novozymes under the trade names Lipolase®, Lipolase® Ultra, LipoPrime®, Lipozyme® and Lipex®.
Another lipase which can be used advantageously is available from the Novozymes company under the trade name Lipoclean®.
Furthermore, for example, the cutinases that were originally isolated from Fusarium solanipisi and Humicola insolens can be used. Lipases that can also be used are available from Amano under the names Lipase CE®, Lipase P®, Lipase B®, or Lipase CES®, Lipase AKG®, Bacillis sp. Lipase®, Lipase AP®, Lipase M-AP® and Lipase AML® available. For example, the lipases or cutinases from the Danisco/Genencor company can be used whose starting enzymes were originally isolated from Pseudomonas mendocina and Fusarium solanii. Other important commercial products are the preparations M1 Lipase® and Lipomax® originally sold by the company Gist-Brocades (now Danisco/Genencor) and those from the company Meito Sangyo KK, Japan, under the name Lipase MY-30®, Lipase OF® and Lipase PL®, as well as the product Lumafast® from Danisco/Genencor.
Other example of commercially available lipases are: Lipex® Evity® EC 100 L, Lipex® Evity® EC 100 T, Lipex® Evity® EC 200 L, Lipex® Evity® 100 L, Lipex® Evity® 100 T, Lipex® Evity® 200 L, PREFERENZ L 100, Biolipasa 2XL, Biolipasa L, Biolipasa P, Lipoclean, Lipolase, Lipolase Ultra.
A lipase preferably comprised in the composition according to the instant invention is Lipex™ 100 L Evity.
Examples of commercially available Phosphodiesterase are: Pristine from Novozyme
Suitable peroxidases/oxidases include those of plant, bacterial or fungal origin. Chemically modified or protein engineered mutants are included. Examples of useful peroxidases include peroxidases from Coprinus, e.g., from C. cinereus, and variants thereof as those described in WO 93/24618, WO 95/10602, and WO 98/15257.
Commercially available peroxidases include Guardzyme™ (Novozymes A/S).
A preferred composition according to the instant invention is characterized in that it comprises the sum of A) and B) in an amount of from 2.0 wt.-% to 60 wt.-%, preferably from 5.0 wt.-% to 40 wt.-%, more preferably from 10.0 wt.-% to 30 wt.-%, as may be the case
A preferred composition according to the instant invention is characterized in that it comprises at least one non-biosurfactant, preferably selected from the group of anionic, cationic, non-ionic, semi-polar, amphoteric and zwitterionic surfactants.
Preferably the non-biosurfactant is selected from the group of fatty alcohol alkoxylates. These can be advantageously used for cleaning a surface of a textile or a fabric containing polyamines.
Non-limiting examples of anionic surfactants include sulfates and sulfonates, in particular, linear alkylbenzenesulfonates (LAS), isomers of LAS, branched alkylbenzenesulfonates (BABS), phenylalkanesulfonates, alpha-olefinsulfonates (AOS), olefin sulfonates, alkene sulfonates, alkane-2,3-diylbis(sulfates), hydroxyalkanesulfonates and disulfonates, alkyl sulfates (AS) such as sodium dodecyl sulfate (SDS), fatty alcohol sulfates (FAS), primary alcohol sulfates (PAS), alcohol ethersulfates (AES or AEOS or FES, also known as alcohol ethoxysulfates or fatty alcohol ether sulfates), secondary alkanesulfonates (SAS), paraffin sulfonates (PS), ester sulfonates, sulfonated fatty acid glycerol esters, alpha-sulfo fatty acid methyl esters (alpha-SFMe or SES) including methyl ester sulfonate (MES), alkyl- or alkenylsuccinic acid, dodecenyl/tetradecenyl succinic acid (DTSA), fatty acid derivatives of amino acids, diesters and monoesters of sulfo-succinic acid or soap, and combinations thereof.
Non-limiting examples of cationic surfactants include alklydimethylethanolamine quat (ADMEAQ), cetyltrimethylammonium bromide (CTAB), dimethyldistearylammonium chloride (DSDMAC), and alkylbenzyldimethylammonium, alkyl quaternary ammonium compounds, alkoxylated quaternary ammonium (AQA) compounds, and combinations thereof.
Non-limiting examples of non-ionic surfactants include alcohol ethoxylates (AE or AEO), which are preferably comprised in the composition according to the instant invention, alcohol propoxylates, propoxylated fatty alcohols (PFA), alkoxylated fatty acid alkyl esters, such as ethoxylated and/or propoxylated fatty acid alkyl esters, alkylphenol ethoxylates (APE), nonylphenol ethoxylates (NPE), alkylpolyglycosides (APG), alkoxylated amines, fatty acid monoethanolamides (FAM), fatty acid diethanolamides (FADA), ethoxylated fatty acid monoethanolamides (EFAM), polyglycerol esters, glycerol esters, propoxylated fatty acid monoethanolamides (PFAM), polyhydroxy alkyl fatty acid amides, or N-acyl N-alkyl derivatives of glucosamine (glucamides, GA, or fatty acid glucamide, FAGA), as well as products available under the trade names SPAN and TWEEN, and combinations thereof.
Non-limiting examples of semipolar surfactants include amine oxides (AO) such as alkyldimethylamineoxide, N-(coco alkyl)-N,N-dimethylamine oxide and N-(tallow-alkyl)-N,N-bis(2-hydroxyethyl)amine oxide, fatty acid alkanolamides and ethoxylated fatty acid alkanolamides, and combinations thereof.
Non-limiting examples of amphoteric and zwitterionic surfactants include betaine, alkyldimethylbetaine, sulfobetaine, hydroxysultaine and combinations thereof.
Furthermore, bio-based surfactants can be included in the composition according to the instant invention, which are not based on glycolipids, for example lipopeptides like surfactins or phospholipids like lecithins.
The composition according to the instant invention can further comprise one or more auxiliary agents selected from the group consisting of bleaching systems, hydrotropes, polymers, which may be synthetic, biopolymers, anti-redeposition aids, fiber protection agents, soil release agents, dye transfer inhibitors, fabric hueing agents, opacifiers, blueing dyes, enzyme stabilizing agents, solvents, viscosity modifiers, preservatives, pH-regulators and salts like NaCl and Na2SO4.
Any polymer known in the art for use in detergents may be utilized. The polymer may function as a co-builder as mentioned above, or may provide antiredeposition, fiber protection, soil release, dye transfer inhibition, viscosity modifiers, grease cleaning and/or anti-foaming properties. Exemplary polymers include (carboxymethyl)cellulose (CMC), poly(vinyl alcohol) (PVA), poly(vinylpyrrolidone) (PVP), poly(ethyleneglycol) or poly(ethylene oxide) (PEG), ethoxylated poly(ethyleneimine), carboxymethyl inulin (CMI), and polycarboxylates such as PAA, PAA/PMA, poly-aspartic acid, and lauryl methacrylate/acrylic acid copolymers, hydrophobically modified CMC (HM-CMC) and silicones, copolymers of terephthalic acid and oligomeric glycols, copolymers of poly(ethylene terephthalate) and poly(oxyethene terephthalate) (PET-POET), PVP, poly(vinylimidazole) (PVI), poly(vinylpyridine-N-oxide) (PVPO or PVPNO) and polyvinylpyrrolidone-vinylimidazole (PVPVI). Further exemplary polymers include sulfonated polycarboxylates, polyethylene oxide and polypropylene oxide (PEO-PPO) and diquaternium ethoxy sulfate. Other exemplary polymers are disclosed in, e.g., WO 2006/130575. Salts of the above-mentioned polymers are also contemplated.
Preferably a composition according to the instant invention is characterized in that it comprises at least one selected from anti-redeposition polymers and soil release polymers, with soil release polymers being preferred. This has the technical effect, that the cleaning capabilities of the composition according to the instant invention is even more enhanced. In combination with glycolipids, which bear one sugar ring in the molecule, e.g. like mono-rhamnolipids and glucolipids of formula (III) a surprising viscosity increase can be observed.
It is preferred in the context of the instant invention, that the anti-redeposition polymer or soil release polymer is selected from the group comprising, preferably consisting of, modified cellulose, preferably carboxymethylcellulose, cellulose acetate and methylcellulose, modified starch, modified inulin, preferably carboxy methyl inulin, polyitaconic acid, polyvinylpyrrolidone, polyvinyl alcohol, and polyethylene glycol, with carboxymethylcellulose and methylcellulose being most preferred.
Further preferred soil release polymers are water soluble polyesters as for example from the TexCare® range commercially available under the name TexCare SRN 260, TexCare SRN 170, TexCare SRN 170 Terra, TexCare SRN 260 SG Terra, TexCare SRN 260 Life and combinations thereof, as well, as the soil release polymers disclosed in EP3218461, EP3218465, EP3489340 and EP3489338.
Further preferred soil release polymers are selected from carboxy methyl inulins. A commercial example is Carboxyline® CMI.
This type of soil release polymer is especially useful in boosting the viscosity build-up, induced by a content of glycolipids, which bear one sugar ring in the molecule, e.g. like mono-rhamnolipids and glucolipids of formula (III).
EP1746109 discloses hybrid polymers of amylose and acrylates, that can also advantageously used in the composition of the instant invention as soil release polymers. A commercial example for this type of soil release polymers is Alcoguard® H 5941.
Non-limiting examples of biopolymers including: starch, like e.g. corn starch, Zea mays starch and tapioca starch, modified starch, like e.g. starch hydroxypropyltrimonium chloride and hydrolyzed corn starch, cellulose, bacterial cellulose, modified cellulose, like e.g. microcrystalline cellulose, hydroxypropyl methylcellulose and cetyl hydroxyethylcellulose, guar gum, pectin, inulin, carrageenan, alginate, galactoarabinan, polycitronellol, carboxymethyl inulin, carboxymethyl cellulose, polyitaconic acid and combinations and salts thereof.
Suitable non-aqueous solvents include monohydric or polyhydric alcohols, alkanolamines or glycol ethers, provided they are miscible with water in the specified concentration range.
The solvents are preferably selected from ethanol, n-propanol, i-propanol, butanols, glycol, propanediol, butanediol, glycerine, diglycol, propyldiglycol, butyldiglycol, hexylene glycol, ethylene glycol methyl ether, ethylene glycol ethyl ether, ethylene glycol propyl ether, n-butyl glycol ether, ethylene glycol mono-glycol ether, Diethylene glycol ethyl ether, propylene glycol methyl ether, propylene glycol ethyl ether, Propylene glycol propyl ether, dipropylene glycol monomethyl ether, dipropylene glycol monoethyl ether, diisopropylene glycol monomethyl ether, diisopropylene glycol monoethyl ether, methoxy triglycol, ethoxy triglycol, butoxy triglycol, 1-butoxyethoxy-2-propanol, n-butoxyethoxy-2-propanol, di-butoxyethoxy-2-propanol, 3-butyl-3-methoxyether solvents, and mixtures of these solvents, butoxyethoxy-2-propanol, 3-butyl-3-butyl ether, propyl glycol, di-octanol ether, di-butoxy-2-propanol, 3-butyl-3-butylether, propanol, propylenglycol, di-butoxyethoxy-2-propanol, di-butoxyethoxy-2-propanol, 3-butoxy-3-methoxyether solvents, diisopropylene glycol monomethylether, diisopropylene glycol monomethylether, and mixtures of these solvents. However, it is preferred that the surfactant preparation contains a polyol as the non-aqueous solvent. The polyol can comprise glycerol, 1,2-propanediol, 1,3-propanediol, ethylene glycol, diethylene glycol and/or dipropylene glycol.
Any preservative known in the art for use in detergents may be utilized. Exemplary preservatives include phenoxyethanol, sodium levulinate, sodium benzoate, p-anisic acid, potassium sorbate, benzoic acid, glyceryl caprylate, capryl glycol, penthylene glycol, methyl propane diol, bronopol, isothiazolinone (methylisothiazolinone, chloromethylisothiazolinone) and combinations thereof
Preferably the composition according to the instant invention comprises one or more encapsulate comprising a benefit agent, preferably a sensorial benefit agent. Preferred encapsulates in this context comprise shear/pressure-sensitive action encapsulates, whereby the sensorial benefit agent is released in response to mechanical force (e.g., friction, pressure, shear stress) on the encapsulate. The encapsulate shell is preferably comprised of materials including but not limited to polyurethane, polyamide, polyolefin, polysaccharide, protein, silicone, lipid, modified cellulose, gums, polyacrylate, polyphosphate, polystyrene, polyesters or combinations of these materials. Preferably the sensorial benefit agent comprises a skin benefit agent or an olfactory benefit agent and/or may be a volatile benefit agent. Sensorial benefit agents may also have benefits for hair and/or hard surfaces and/or fabrics. The sensorial benefit may have anti-foam properties, and as such it is advantageous for foaming purposes that it is encapsulated so as not interfering with the foam until release by rubbing. Suitable volatile benefit agents include but are not limited to perfumes, insect repellents, essential oils, sensates such as menthol and aromatherapy actives, preferably perfumes. Mixtures of volatile benefit agents may be used. The total amount of benefit agent is preferably from 0.01 to 10% by weight, more preferably from 0.05 to 5% by weight, even more preferably from 0.1 to 4.0%, most preferably from 0.15 to 4.0% by weight, based on the total weight of the composition. The preferred benefit agent is a perfume. The composition of the instant invention may also comprise an unconfined (also called non-encapsulated) volatile benefit agent. Where the volatile benefit agent is a perfume, the perfumes described below are suitable for use as the encapsulated volatile benefit agent and also as the unconfined perfume component.
Preferably the composition according to the instant invention has a viscosity in the range of from 5 to 400, preferably of from 10 to 350, preferably of from 15 to 300, mPas (measured: Brookfield LV, s61, 200 rpm, 20° C.).
Preferably the composition according to the instant invention has a turbidity of from 0.005 to 5000, preferably of from 11.0 to 100, Nephelometric Turbidity Units. The measurement of turbidity is conducted with a 2100Q Portable Turbidimeter which measures the intensity of light scattered at 90 degrees as a beam of light passes through a liquid sample, giving a direct response in NTU. The NTU is a unit measuring the lack of clarity of liquids and is used by water and sewage treatment plants, in marine studies, for example. For example, water containing 1 milligram of finely divided silica per liter has a turbidity of 1 NTU. The water to be measured is placed in a standard container. A light beam passes through the water and strikes a sensor on the other side of the container. A second sensor is mounted at right angles to the beam, measuring light scattered by particles in the water. From the ratio between the light intensities at the two sensors the turbidity in NTU can be calculated.
The composition as contemplated herein preferably is a detergent composition. It may be in any convenient form, e.g., a bar, a homogenous tablet, a tablet having two or more layers, a pouch having one or more compartments, a regular or compact powder, a granule, a paste, a gel, or a regular, compact or concentrated liquid. There are a number of detergent formulation forms such as layers (same or different phases), pouches, as well as forms for machine dosing unit. Pouches can be configured as single or multicompartment. It can be of any form, shape and material which is suitable for hold the composition, e.g. without allowing the release of the composition from the pouch prior to water contact. The pouch is made from water soluble film which encloses an inner volume. Said inner volume can be divided into compartments of the pouch. Preferred films are polymeric materials preferably polymers which are formed into a film or sheet. Preferred polymers, copolymers or derivates thereof are selected polyacrylates, and water-soluble acrylate copolymers, methyl cellulose, carboxy methyl cellulose, sodium dextrin, ethyl cellulose, hydroxyethyl cellulose, hydroxypropyl methyl cellulose, malto dextrin, poly methacrylates, most preferably polyvinyl alcohol copolymers and, hydroxypropyl methyl cellulose (HPMC). Preferably the level of polymer in the film for example PVA is at least about 60%. Preferred average molecular weight will typically be from about 20,000 to about 150,000. Films can also be of blend compositions comprising hydrolytically degradable and water-soluble polymer blends such as polyactide and polyvinyl alcohol (known under the Trade reference M8630 as sold by Chris Craft In. Prod. Of Gary, Ind., US) plus plasticizers like glycerol, ethylene glycerol, Propylene glycol, sorbitol and mixtures thereof. The pouches can comprise a solid laundry detergent composition or part components and/or a liquid cleaning composition or part components separated by the water-soluble film. The compartment for liquid components can be different in composition than compartments containing solids, see for example US20090011970.
Detergent ingredients can be separated physically from each other by compartments in water dissolvable pouches or in different layers of tablets. Thereby negative storage interaction between components can be avoided. Different dissolution profiles of each of the compartments can also give rise to delayed dissolution of selected components in the wash solution.
The detergent composition according to the instant invention can be in form of a laundry soap bar and used for hand washing laundry, fabrics and/or textiles. The term laundry soap bar includes laundry bars, soap bars, combo bars, syndet bars and detergent bars. The types of bar usually differ in the type of surfactant they contain, and the term laundry soap bar includes those containing soaps from fatty acids and/or synthetic soaps. The laundry soap bar has a physical form which is solid and not a liquid, gel or a powder at room temperature. The term solid is defined as a physical form which does not significantly change over time, i.e. if a solid object (e.g. laundry soap bar) is placed inside a container, the solid object does not change to fill the container it is placed in. The bar is a solid typically in bar form but can be in other solid shapes such as round or oval.
The detergent composition according to the instant invention can be formulated as a granular detergent as described in WO09/092699, EP1705241, EP1382668, WO07/001262, U.S. Pat. No. 6,472,364, WO04/074419 or WO09/102854.
The detergent composition according to the instant invention preferably is in the form of a liquid or gel detergent. This may be aqueous, typically containing at least 20% by weight water, with the percentages referring to the total composition. Other types of liquids, including without limitation, alkanols, amines, diols, ethers and polyols may be included in an aqueous liquid or gel. An aqueous liquid or gel detergent composition may contain from 0-30 wt.-% organic solvent, with the percentages referring to the total composition. A liquid or gel detergent may be non-aqueous.
A preferred composition according to the invention is characterized in that the pH of the composition at 25° C. is from 3.0 to 10.0, preferably from 4.0 to 9.5 and particularly preferably from 7.0 to 9.0.
The “pH” in connection with the present invention—unless stated otherwise—is defined as the value which is measured for the relevant composition at 25° C. after stirring for five minutes using a pH electrode calibrated in accordance with ISO 4316 (1977).
The instant invention further provides a process for cleaning a surface of an article, preferably a textile or a fabric, comprising the steps of
A preferred process according to the instant invention is characterized in that the weight ratio of the provided article and water in step b) and c) are in the range of from 1:2 to 1:30, preferably from 1:3 to 1:25, more preferably from 1:4 to 1:20.
A preferred process according to the instant invention is characterized in that in step b) per kg of water 0.1 g to 50 g, preferably 1.0 g to 20 g, more preferably 2.0 g to 10 g, composition according to the instant invention are provided.
The instant invention further provides the use of a composition according to the instant invention for cleaning a surface of an article, preferably a textile or a fabric.
Preferably the use according to the instant invention is characterized in that the surface of the article is cleaned from fat and/or oil, preferably from solid fatty stains.
The examples adduced hereinafter describe the present invention by way of example, without any intention that the invention, the scope of application of which is apparent from the entirety of the description and the claims, be restricted to the embodiments specified in the examples.
Rhamnolipids used were prepared as described in example 1 of EP3061442 and resemble di-rhamnolipids; mono-rhamnolipids were prepared as in example 2 of EP3061442.
The sophorolipid used is a sophorolipid REWOFERM SL ONE from Evonik, which has a lactone to acid ratio of 40:60.
Glucolipids were produced according to example 2 of WO2019154970 via fermentation
The following formulations were prepared with the numbers given being weight percentages of active matter, Benchmark 1 and Benchmark 2 (commercially available detergents) as well as Benchmark 3, Benchmark 4 and Benchmark 5 (internal available detergents) being not according to the invention, Detergent 1-6 according to the invention:
For the evaluation of the compositions in table 1 and 2, a stain removal test using the Linitest device, has been carried out.
A Linitest device was used for the test
The used stains were purchased form CFT (Vlaardingen, Nederland's) which was also recommended by A.I.S.E (Laundry Detergent Testing Guidelines)
After the washing, the fabrics were rinsed and then dried in the air.
The evaluation of the degree of stain removal was carried out measuring the reflectance via spectrophotometer, using the Y-value of the Y, x, y color coordinates measurement, light source D65 with a UV cut-off filter at 420 nm. Aperture used for real stains 15 mm (minimum 12 mm). Stains were measured unfolded, 3 measurements per stain (in the center of the circular area, or closest homogenous area) so 18 times per stain. Measurements were taken on each stain before wash (to verify quality of stains) and after the wash and to evaluate standard deviations and are reported.
Results are expressed as the mean of value Y between three replicates and its standard deviation (σ) and shown in table 8 to 14. The better the soil removal, the larger the Y value.
2
indicates data missing or illegible when filed
It was surprisingly found that the addition of the component persicomycin to the biosurfactant-based detergent formulation will lead to a better cleaning performance with regards to stain removal. Especially in the case of fatty stains the combination outperformed both the formulations without persicomycin (Benchmarks 3, 4 and 5) and commercially available formulations (Benchmarks 1 and 2). Moreover, the addition of persicomycin is leading to a higher overall formulation viscosity that would very much fit with market and consumer expectations for liquid laundry detergents.
| Number | Date | Country | Kind |
|---|---|---|---|
| 22181475.9 | Jun 2022 | EP | regional |
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/EP2023/066371 | 6/19/2023 | WO |
