Claims
- 1. A topical composition, comprising at least L-2-oxothiazolidine-4-carboxylic acid (I), and at least one polyol (II), the amounts by weight of compounds (I) and (II) being in the relationship: (I)/(II).ltoreq.1/3.
- 2. The topical composition of claim 1, wherein said L-2-oxothiazolidine-4-carboxylic acid is present in an amount of from about 0.1 to 10% by weight based upon the total weight of the composition.
- 3. The topical composition of claim 2, wherein said L-2-oxothiazolidine-4-carboxylic acid is present in an amount of from about 2 to 5% by weight.
- 4. The topical composition of claim 1, which is in a form of an aqueous solution, aqueous-alcoholic solution, oily solution, oil-in-water emulsion, water-in-oil solution, aqueous gel, oily gel or vesicle dispersion.
- 5. The topical composition of claim 1, which further comprises one or more of fatty substances, preserving agents, vitamins, gelling agents, fragrances, surfactants, water, antioxidants, fillers, moisturizers or screening agents.
- 6. The topical composition of claim 5, wherein said fatty substance comprises an oil, wax, silicone, fatty alcohol or fatty acid.
- 7. The topical composition of claim 1, wherein said one or more polyols are selected from the group consisting of linear-, branched- and cyclic-saturated or unsaturated polyhydroxylated compounds having from 2 to 12 carbon atoms, and polyethers of said polyhydroxylated compounds.
- 8. The topical composition of claim 1, wherein said oil comprises mineral oil, liquid petroleum or jojoba oil.
- 9. The topical composition of claim 7, which comprises in % by weight:
- ______________________________________L-2-oxothiazolidine-4-carboxylic acid 5 Jojoba oil 13 Sipol wax 6 Isopropyl palmitate 2 Glycerol 15 Alkyl paraben 0.5 Fragrance 1 Water 100.______________________________________
- 10. The topical composition of claim 1, wherein said polyol is selected from the group consisting of glycerol, sorbitol, ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, pentylene glycol, butylidiglycol, 1,2,3-trihydroxyhexane, dipropylene glycol and hexaglycerol.
- 11. The topical composition of claim 1, wherein the ratio (I)/(II).ltoreq.1/4.
- 12. The topical composition of claim 1, which further comprises water.
- 13. The topical composition according to claim 12, wherein the amount of water is less than or equal to 35% by weight relative to the total weight of the composition.
- 14. The topical composition of claim 12, which is suitable for the depigmentation or bleaching of human skin or of human hair.
- 15. The topical composition of claim 12, which is suitable for prevention of hair loss or to stimulate the regrowth of the hair.
- 16. The topical composition of claim 12, wherein the aqueous phase is neutralized by adjusting its pH to a value between about 6 and 8.
- 17. A method of depigmenting or bleaching mammalian skin or both, which comprises administering to the skin of a mammal in need of depigmenting or bleaching or both an effective amount of a composition which comprises an amount of L-2-oxothiazolidine-4-carboxylic acid (I), and at least one polyol (II), the amount by weight of compounds (I) and (II) being in the relationship: (I)/(II).ltoreq.1/3.
- 18. The method of claim 17, wherein said L-2-oxothiazolidine-4-carboxylic acid is in a cosmetic composition comprising from about 0.1 to 10% by weight based upon the total weight of the composition.
- 19. The method of claim 17, wherein said mammal is a human.
- 20. The method of claim 18, wherein said L-2-oxothiazolidine-4-carboxylic acid is present in an amount of from about 2 to 5% by weight.
- 21. The method of claim 17, wherein said composition is topically administered.
- 22. The method of claim 17, wherein said composition is aerosolically administered.
- 23. The method of claim 17, wherein said polyol of said composition is selected from the group consisting of glycerol, sorbitol, ethylene glycol, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, butyldiglycol, 1,2,3-trihydroxyhexane, dipropylene glycol and hexaglycerol.
Priority Claims (1)
Number |
Date |
Country |
Kind |
95 15335 |
Dec 1995 |
FRX |
|
Parent Case Info
The present application is a continuation-in-part (CIP) Application of application Ser. No. 08/773,514, filed on Dec. 23, 1996.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
RE34185 |
Amick |
Feb 1993 |
|
Foreign Referenced Citations (2)
Number |
Date |
Country |
0 656 201 |
Jun 1995 |
EPX |
0 780 120 |
Jun 1997 |
EPX |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
773514 |
Dec 1996 |
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