Claims
- 1. A deliverable composition comprising: an amphipathic compound, a polycation selected from the group consisting of polyvinylamine and polyallylamine, and an siRNA.
- 2. The composition of claim 1 wherein the amphipathic compound has the structure comprising:
- 3. The composition of claim 2 wherein R1 and R2 of the amphipathic compound are the same.
- 4. The composition of claim 2 wherein R1 and R2 of the amphipathic compound of are different.
- 5. A process for delivering a siRNA to an animal cell comprising: associating the cell with a composition comprising an amphipathic compound, an effective amount of a polycation selected from the group consisting of polyvinylamine and polyallylamine, and a siRNA in solution.
- 6. The process of claim 6 wherein the animal cell is in vivo.
- 7. A process of claim 6 wherein the animal cell is in vitro.
- 8. The process of claim 6 wherein the animal cell is ex vivo.
- 9. The process of claim 6 wherein the animal cell is a mammalian cell.
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is a Continuation-In-Part of U.S. application Ser. No. 10/186,757 filed Jul. 1, 2002, U.S. application Ser. No. 10/157,674 filed May 23, 2002, and U.S. application Ser. No. 10/345,021 filed Jan. 15, 2003.
Continuation in Parts (3)
|
Number |
Date |
Country |
Parent |
10186757 |
Jul 2002 |
US |
Child |
10621760 |
Jul 2003 |
US |
Parent |
10157674 |
May 2002 |
US |
Child |
10621760 |
Jul 2003 |
US |
Parent |
10345021 |
Jan 2003 |
US |
Child |
10621760 |
Jul 2003 |
US |