Claims
- 1. A composition comprising:(A) at least one active agent; and (B) a compound having the following formula or a salt thereof.
- 2. A composition as defined in claim 1, wherein said active agent is selected from the group consisting of a biologically active agent, a chemically active agent, and a combination thereof.
- 3. A composition as defined in claim 2, wherein said biologically active agent comprises at least one peptide, hormone, polysaccharide, mucopolysaccharide, carbohydrate, or lipid.
- 4. The composition as defined in claim 3, wherein said biologically active agent is selected from the group consisting of human growth hormone, bovine growth hormone, growth hormone-releasing hormone, an interferon, interleukin-1, interleukin-II, insulin, heparin, low molecular weight heparin, calcitonin, erythropoietin, atrial naturetic factor, an antigen, a monoclonal antibody, somatostatin, adrenocorticotropin, gonadotropin releasing hormone, oxytocin, vasopressin, cromolyn sodium, vancomycin, parathyroid hormone, desferrioxamine, an anti-microbial agent, an anti-fungal agent, and any combination thereof.
- 5. A composition as defined in claim 4, wherein said biologically active agent comprises an interferon, interleukin-II, insulin, heparin, low molecular weight heparin, calcitonin, oxytocin, vasopressin, vancomycin, DFO, parathyroid hormone, or a combination thereof.
- 6. A composition as defined in claim 2, wherein said biologically active agent comprises parathyroid hormone.
- 7. A composition as defined in claim 2, wherein said biologically active agent comprises recombinant human growth hormone.
- 8. A composition as defined on claim 2, wherein said biologically active agent comprises interferon.
- 9. A composition as defined in claim 2, wherein said biologically active agent comprises heparin.
- 10. A composition as defined in claim 2, wherein said biologically active agent it comprises low molecular weight heparin.
- 11. A composition as defined in claim 1, wherein said compound comprises a poly(amino acid).
- 12. A composition as defined in claim 1, wherein said compound comprises a polypeptide.
- 13. A dosage unit form comprising:(A) a composition as defined in claim 1; and (B) (a) an excipient (b) a diluent, (c) a disintegrant, (d) a lubricant, (e) a plasticizer, (f) a colorant, (g) a dosing vehicle, or (h) any combination thereof.
- 14. The dosage unit form as defined in claim 13, wherein said active agent is selected from the group consisting of a biologically active agent, a chemically active agent, and a combination thereof.
- 15. The dosage unit form as defined in claim 14, wherein said biologically active agent comprises at least one peptide, hormone, polysaccharide, mucopolysaccharide, carbohydrate, or lipid.
- 16. The dosage unit form as defined in claim 15, wherein said biologically active agent is selected from the group consisting of human growth hormone, bovine growth hormone, growth hormone-releasing hormone, an interferon, interleukin-1, interleukin-II, insulin, heparin, low molecular weight heparin, calcitonin, erythropoietin, atrial naturetic factor, an antigen, a monoclonal antibody, somatostatin, adrenocorticotropin, gonadotropin releasing hormone, oxytocin, vasopressin, cromolyn sodium, vancomycin, parathyroid hormone, desferrioxamine, an anti-microbial agent, an anti-fungal agent, and any combination thereof.
- 17. A dosage unit form as defined in claim 16, wherein said biologically active agent comprises an interferon, interleukin-II, insulin, heparin, low molecular weight heparin, calcitonin, oxytocin, vasopressin, vancomycin, DFO, parathyroid hormone, or a combination thereof.
- 18. A dosage unit form as defined in claim 14, wherein said biologically active agent comprises parathyroid hormone.
- 19. A dosage unit form as defined in claim 14, wherein said biologically active agent comprises recombinant human growth hormone.
- 20. A dosage unit form as defined on claim 14, wherein said biologically active agent comprises interferon.
- 21. A dosage unit form as defined in claim 14, wherein said biologically active agent comprises heparin.
- 22. A dosage unit form as defined in claim 14, wherein said biologically active agent comprises low molecular weight heparin.
- 23. A dosage unit form as defined in claim 13, comprising a tablet, a capsule, or a liquid.
- 24. A dosage unit form as defined in claim 23, wherein said dosing vehicle is selected from the group consisting of water, 1,2-propane diol, ethanol, and any combination thereof.
- 25. A method for administering a biologically-active agent to an animal in need of said agent, said method comprising administering orally to said animal a composition as defined in claim 2.
- 26. A compound having the formula or a salt thereof.
- 27. A method for preparing a composition, said method comprising mixing:(A) at least one active agent; (B) at least one compound as defined in claim 26, and (C) optionally, a dosing vehicle.
- 28. A composition comprising:(A) at least one active agent; and (B) a poly(amino acid) comprising a monomer having the formula or a salt thereof.
- 29. A composition as defined in claim 28, wherein the poly(amino acid) comprises a peptide.
Parent Case Info
This is a continuation of U.S. application Ser. No. 09/305,506, filed May 5, 1999, which is a continuation of U.S. application Ser. No. 08/798,031, filed Feb. 6, 1997, now U.S. Pat. No. 6,001,347, which is a continuation of PCT application Ser. No. PCT/US96/04580, filed Apr. 1, 1996, published as International Publication No. WO 96/30036, which is a continuation-in-part of application Ser. No. 08/414,654, filed Mar. 31, 1995, now U.S. Pat. No. 5,650,386, and which claims the benefit to application Ser. No. 60/003,111, filed Sep. 1, 1995, and application Ser. No. 60/017,902, filed Mar. 29, 1996.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
6071510 |
Leone-Bay et al. |
Jun 2000 |
A |
Foreign Referenced Citations (3)
Number |
Date |
Country |
56-118050 |
Sep 1981 |
JP |
59-196849 |
Nov 1984 |
JP |
7-138219 |
May 1995 |
JP |
Provisional Applications (2)
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Number |
Date |
Country |
|
60/017902 |
Mar 1996 |
US |
|
60/003111 |
Sep 1995 |
US |
Continuations (3)
|
Number |
Date |
Country |
Parent |
09/305506 |
May 1999 |
US |
Child |
10/142009 |
|
US |
Parent |
08/798031 |
Feb 1997 |
US |
Child |
09/305506 |
|
US |
Parent |
PCT/US96/04580 |
Apr 1996 |
US |
Child |
08/798031 |
|
US |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
08/414654 |
Mar 1995 |
US |
Child |
PCT/US96/04580 |
|
US |