Claims
- 1. A method of treating inflammation in a human or animal, wherein said method comprises administering to said human or animal an effective amount of a compound having the following formula:
- 2. The method, according to claim 1, wherein said compound has the following structure:
- 3. The method, according to claim 2, wherein said compound has the following structure:
- 4. The method, according to claim 1, wherein said method is used to treat inflammation in which the primary activating inflammation is of neurogenic origin.
- 5. The method, according to claim 4, wherein said method is used to block a nociceptive inflammatory pathway.
- 6. The method, according to claim 1, wherein said compound is administered as a pharmaceutical composition, said pharmaceutical composition comprising one or more compounds of claim 1 and an acceptable pharmaceutical carrier.
- 7. The method, according to claim 1, wherein said compound is administered as a cosmetic composition.
- 8. An anti-inflamatory composition comprising a compound having the formula:
- 9. The composition, according to claim 8, wherein said compound has the following structure:
- 10. The composition, according to claim 9, wherein said compound has the following structure:
- 11. The composition, according to claim 8, wherein said composition further comprises a second active ingredient.
- 12. The composition, according to claim 11, wherein said second active agent is selected from the group consisting of a steroidal anti-inflammatory compound, a non-steroidal anti-inflammatory compound, an antiviral compound, an antibacterial compound, an antifungal compound, and an anti-tumor compound.
- 13. The composition, according to claim 8, wherein said compound is about 0.1% to about 45% weight percent of said composition.
- 14. The composition, according to claim 13, wherein said compound is about 1% to about 25%, weight percent, of said composition.
- 15. A compound having the following structure:
- 16. The compound, according to claim 15, wherein said compound has the following structure:
- 17. A method for treating a condition, in a human or animal, wherein said condition is selected from the group consisting of pain, burns, allergic responses, wound healing, anaphylactic reactions, inflammatory bowel disease, nephritis, conjunctivitis, inflammatory gum disease, and acute asthmatic attack and inflammation of the lung due to chemical exposure, said method comprising administering an effective amount of a bis-heterocyclic compound or a salt, analog, or derivative thereof, wherein said compound is selected from the group consisting of
- 18. The method, according to claim 17, wherein said pain is caused by a condition selected from the group consisting of migraine, rhinitis, thermal induced pain, radiation induced pain, and chemical induced pain.
- 19. The method, according to claim 17, wherein said burn is selected from the group consisting of chemical burns, chemical induced lesions, radiation bums, and thermal bums.
- 20. The method, according to claim 17, wherein said condition is allergic response.
- 21. The method, according to claim 17, wherein said treatment facilitates the promotion of wound healing.
- 22. The method, according to claim 17, wherein said condition is a systemic anaphylactic reaction in an animal or a human.
- 23. The method, according to claim 17, wherein said condition is inflammatory bowel disease.
- 24. The method, according to claim 17, wherein said condition is nephritis.
- 25. The method, according to claim 17, wherein said condition is conjunctivitis.
- 26. The method, according to claim 17, wherein said condition is inflammatory gum disease.
- 27. The method, according to claim 17, wherein said condition is selected from the group consisting of acute asthmatic attack and inflammation of the lung from chemical exposure.
CROSS-REFERENCE TO A RELATED APPLICATION
[0001] This application is a continuation of application Ser. No.09/253,118, filed Feb. 19, 1999; which claims priority to provisional patent application Ser. No. 60/091,990, filed Jul. 8, 1998; and Ser. No. 60/075,476, filed Feb. 20, 1998.
DESCRIPTION
[0002] The subject invention was made with government support under a research project supported by NOAA Grant No. NA36RG0537. The government has certain rights in this invention.
Provisional Applications (2)
|
Number |
Date |
Country |
|
60091990 |
Jul 1998 |
US |
|
60075476 |
Feb 1998 |
US |
Continuations (1)
|
Number |
Date |
Country |
Parent |
09253118 |
Feb 1999 |
US |
Child |
09944881 |
Aug 2001 |
US |