Number | Date | Country | Kind |
---|---|---|---|
9912413 | May 1999 | GB |
Number | Name | Date | Kind |
---|---|---|---|
4081450 | Zimmerman | Mar 1978 | A |
4191771 | Zimmerman | Mar 1980 | A |
4737505 | Guillaume et al. | Apr 1988 | A |
5136040 | Werner | Aug 1992 | A |
5498718 | Werner | Mar 1996 | A |
Number | Date | Country |
---|---|---|
4341403 | Jun 1995 | DE |
0013078 | Jul 1980 | EP |
0136863 | Apr 1985 | EP |
0506468 | Mar 1992 | EP |
0506468 | Mar 1992 | EP |
0287339 | Aug 1994 | EP |
0657428 | Jun 1995 | EP |
0506478 | Sep 1997 | EP |
0938898 | Sep 1999 | EP |
2038812 | Jul 1980 | GB |
9515327 | Jun 1995 | WO |
9603400 | Feb 1996 | WO |
9850358 | Nov 1998 | WO |
9959971 | Nov 1999 | WO |
9967237 | Dec 1999 | WO |
0039089 | Jul 2000 | WO |
Entry |
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Charles H. Mitch, et al.; 3,4-Dimethyl-4-(3-hydroxyphenyl)piperidines: Opioid Antagonists with Potent Anorectant Activity; J. Med. Chem. (1993) 36, 2842-2850. |
Dennis M. Zimmerman, et al.; Structure-Activity Relationships of trans-3,4-Dimethyl-4-(3-hydroxyphenyl)piperidine Antagonists for μ-and K-Opioid Receptors; J. Med. Chem (1993) 36, 2833-2841. |
Patent Abstract of Japan, vol. 13, No. 179 (C-590), 1988. |