The present invention relates to x-ray computed tomography (CT) and specifically to a CT system and method providing high-speed data acquisition.
Conventional x-ray computed tomography may employ an x-ray source collimated to produce a narrow fan-shaped beam directed along the transverse plane through a patient to be received by linear multi-element detector array.
The x-ray source and detector array may be mounted on a gantry to be rotated about a patient to obtain “projections” measuring x-ray attenuation at the different gantry angles along a slice plane though the patient. A “projection set” of projections obtained over a range of gantry rotation of 180 degrees plus the angle subtended by the fan beam, may be “reconstructed” into a tomographic image. The tomographic image shows a cross section of the patient along the slice plane.
Reconstructions using too few projections or a limited number of gantry angles may produce images with “artifacts”, typically streaks, that mar the tomographic image.
In a normal CT acquisition, multiple projection sets are obtained along different, sequential slice planes by movement of the patient within the gantry along the z-axis. The slices may be assembled to provide data for an arbitrary volume of the patient which may then be reconstructed into cross-sectional images along arbitrary planes.
The time required to collect projection data over a volume using conventional fan-beam tomography can be substantial and may preclude the use of tomography in situations where large volumes are to be monitored in real-time (for example, in dynamic contrast enhanced studies) or where there is unavoidable patient or organ motion during the acquisition time (for example, cardiac studies).
One method of increasing CT acquisition speed is by using a spiral or helical scan in which the gantry containing the x-ray source and detector is rotated continuously as the patient is moved along the z-axis. This process eliminates the need for stopping and starting the gantry and table.
Wider fan beams known as cone beams may also be used with rectangular detector arrays having, for example, 500 or 1,000 detector elements in the scan plane and sixteen detector elements disposed along the z-axis, perpendicular to the scan plane. This arrangement allows multiple slices to be collected at one time but the z-axis extent of the acquisition is very limited unless the patient table is moved during the scan.
Another approach is the electron beam CT scanner in which a rotating x-ray source is generated without mechanical motion of a gantry. Instead, as shown in U.S. Pat. Nos. 4,352,021; 4,672,649; 6,130,929; 5,491,734; 5,504,791; 5,504,791; 6,009,141; 5,172,401; and 4,158,142 the electron beam is directed to stationary anodes around the subject to produce x-rays from the desired projection angles. Although these “EBCT” systems acquire a 2D slice image very rapidly, the patient table must be moved to acquire additional slice images along the z-axis.
The commercially available scanners are thus not very fast in acquiring x-ray attenuation data over a region of interest (ROI) that is extended in the direction of table motion. One such clinical application, for example, is a contrast enhanced dynamic study of vasculature in the trunk or legs of a subject. In this clinical application it is desirable to acquire data from the extended ROI at a high frame rate so that the inflow of contrast can be observed in a series of images. This is not possible if the table must be moved during the scan to cover the entire ROI. Another clinical application is cardiac imaging in which attenuation data must be obtained over a 3D volume in very short time intervals in order to “capture” the cardiac structures at very specific cardiac phases. This cannot be done well if the scan must be repeated at two or more patient table locations to cover the ROI along the z-axis.
The present invention is a CT system having an x-ray source that not only produces a cone beam that projects through the subject and is detected by a two-dimensional array of detector elements, but also is electronically moved along the z-axis to substantially increase the ROI without the need for table motion. As the x-ray source and 2D detector array are rotated around the gantry during the scan, the x-ray source is moved along the z-axis to acquire data from an ROI that is much larger than that acquired by a rotated cone beam.
A general object of the invention is to acquire x-ray attenuation data over a cylindrical volume in a controlled and prescribed manner. Depending on the clinical application, the physical rotation of the x-ray source around the subject and the linear electronic motion of the x-ray source along the z-axis can be controlled to implement many different acquisition strategies.
Another object of the invention is to rapidly acquire x-ray attenuation data over a very large ROI. A dynamic study can be performed from which a plurality of images are reconstructed depicting changes in the subject at a high frame rate. In a contrast enhanced CT study, for example, the in-flow of contrast can be seen in vasculature that extends a substantial distance along the z-axis.
Another object of the invention is to acquire x-ray attenuation data of the entire heart during a gated cardiac scan. The electronic scan along the z-axis enables data to be acquired from the entire heart over a very short time interval at any cardiac phase. Blurring due to cardiac motion is reduced.
The foregoing and other objects and advantages of the invention will appear from the following description. In the description, reference is made to the accompanying drawings which form a part hereof, and in which there is shown by way of illustration a preferred embodiment of the invention. Such embodiment does not necessarily represent the full scope of the invention, however, and reference is made therefore to the claims and herein for interpreting the scope of the invention.
With initial reference to
The rotation of the gantry and the operation of the x-ray source 13 are governed by a control mechanism 20 of the CT system. The control mechanism 20 includes an x-ray controller 22 that provides power and timing signals to the x-ray source 13 and a gantry motor controller 23 that controls the rotational speed and position of the gantry 12. A data acquisition system (DAS) 24 in the control mechanism 20 samples analog data from detector elements 18 and converts the data to digital signals for subsequent processing. An image reconstructor 25, receives sampled and digitized x-ray data from the DAS 24 and performs high speed image reconstruction. The reconstructed image is applied as an input to a computer 26 which stores the image in a mass storage device 29.
The computer 26 also receives commands and scanning parameters from an operator via console 30 that has a keyboard. An associated cathode ray tube display 32 allows the operator to observe the reconstructed image and other data from the computer 26. The operator supplied commands and parameters are used by the computer 26 to provide control signals and information to the DAS 24, the x-ray controller 22 and the gantry motor controller 23. In addition, computer 26 operates a table motor controller 34 which controls a motorized table 36 to position the patient 15 in the gantry 12.
Referring particularly to
Opposite the detector array 16 is the x-ray source 13, which in this preferred embodiment is comprised of an electron gun 40 and an anode assembly 42. As shown best in
Mounted adjacent the rotating anode 44 is a stationary, pre-patient collimator 48. The collimator 48 is constructed of a metal which shields x-rays and includes downward extending, wedge-shaped lobes 50 that are spaced equidistantly along the length of the anode 44. Anode segments are exposed between the lobes 50 and when an electron beam strikes one of the anode segments, a cone beam of x-rays 52 is produced and extends between the adjacent collimator lobes 50 and into a cylindrical region of interest 54. As will be discussed in more detail below, the electron beam can be moved quickly to strike any of the exposed anode segments, and the cone beam 52 can thus be moved electronically along the z-axis to different locations. The anode assembly 42 is also rotated around the region of interest 54 as the gantry 12 rotates. The cone beam 52 which it produces can thus intersect the region of interest 54 at any view angle. As shown in
Referring again to
While a single electron gun 40 is used in the preferred embodiment and controlled by the x-ray controller 22 (
Referring still to
As shown in
Referring particularly to
It should be apparent, however, that if the scan pattern of
One solution to the undersampling problem is to use a scan pattern in which multiple gantry rotations are performed during the movement of the scan point 58 along the z-axis. Such a scan pattern 90 is illustrated in
Referring particularly to
Unlike the first embodiment described above, this second embodiment employs separate electron beam sources 144 for the ten separate anode segments. The electron beam sources 144 are each switched on and off during a scan by an electron switch 146 that is operated by the x-ray controller 22 (
Another distinction between the first and second embodiment is the shape of the cone beam that is produced. As shown best in
Dynamic Study
Another scanning strategy that may be used is to interleave the scan patterns during sequential acquisition of image frames during a dynamic study. Referring to
The interleaved acquisition is particularly useful to perform a dynamic study where images are acquired quickly in succession in order to see changes that occur in the subject. A contrast enhanced dynamic study is an example clinical application. In this application a plurality of interleaved scan patterns are selected and each acquires an image at the desired frame rate. In this example, each scan pattern is completed in three gantry revolutions to provide a frame time of 1.5 seconds and because successive images are acquired at different, interleaved view angles, successively acquired data sets contain data measured at different view angles.
Because successive images are acquired with interleaved scan patterns, image artifacts can be reduced or suppressed by filling in missing data with data acquired from a successive image acquisition. For example, if image artifacts restrict the clinical usefulness of one image in a series of images in dynamic study, projections from temporally adjacent image data sets may be combined with its acquired data set to add more projection angles. Artifacts due to undersampling will be reduced in the reconstructed image. While such a straight forward combination of acquired data from successive, interleaved data sets may suppress image artifacts, it may also reduce the time resolution of the image. In other words, two combined data sets may have a frame time of one second rather than a frame time of 0.5 seconds. This may or may not be a problem depending on how rapidly the changes are occurring in the subject at this point in the dynamic study.
A more sophisticated method may also be used to combine interleaved data sets without significantly reducing time resolution. With this method each interleaved, undersampled acquired data set is first converted to a k-space data set. This can be done for example by reconstructing the image in a conventional manner and then Fourier transforming the image to k-space. It is a characteristic of k-space data sets acquired with three-dimensional projections that the center of k-space becomes fully sampled before peripheral k-space. It is also a characteristic of k-space that the peripheral k-space data does not significantly impact the appearance of large shapes in the final image. Therefore, peripheral k-space data can be shared between successive, interleaved k-space data sets to fill up, or provide more fully sampled k-space data sets without changing the effective time resolution of the succession of images. Each combined k-space data set is then used to reconstruct a 3D image by performing a 3D Fourier transformation. The resulting images have reduced image artifacts and the time resolution is not substantially changed because the changes in large shapes that occur during the dynamic study are not affected by sharing peripheral k-space data.
In the preferred embodiment only two different interleaved scan patterns are employed during the dynamic study. This enables the data from any two successive data sets to be combined as described above. In some clinical applications it may be preferable to use more than two different interleaved scan patterns and data may be combined from more than two successively acquired data sets. To avoid unduly reducing the time resolution of the dynamic study the peripheral k-space data sharing method should be used when combining data from more temporally remote data sets. For example, peripheral data extending closer to the center of k-space may be combined from temporally adjacent data sets, whereas peripheral k-space more remote from the center of k-space may be combined from data sets acquired more remote in time from the image frame being reconstructed. This method of combining k-space data is illustrated in
Cardiac Study
Another clinical application of the present invention is in cardiac gated studies of the heart. Because the heart is moving rapidly a gating signal is used to trigger the acquisition of views at specific phases of the cardiac cycle. Referring particularly to
Referring particularly to
Referring still to
At the completion of the scan, data for each cardiac phase image has been acquired. It includes data that covers the entire z-axis extent of the ROI 54 and with view angles distributed substantially evenly around the ROI. This 3D attenuation data set is used to reconstruct a 3D image using conventional cone beam reconstruction methods.
It should be apparent that many other scan patterns may be implemented using the present invention to accommodate the particular needs of other clinical applications. Also, in most applications no table motion is needed due to the z-axis extent of the electronically moved x-ray cone beam, but there still may be clinical applications where some table movement is employed. It should also be apparent that other types of x-ray sources may be employed, such as transmission type x-ray sources rather than the reflective type x-ray sources employed in the preferred embodiment.
This application claims the benefit of U.S. Provisional patent application Ser. No. 60/518,530 filed on Nov. 7, 2003 and entitled “Computed Tomography With Z-Axis Scanning”.
This invention was made with United States government support awarded by the following agencies: NIH HL62425. The United States has certain rights in this invention.
Number | Date | Country | |
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60518530 | Nov 2003 | US |