The shipment of temperature sensitive goods may be accomplished by placing the temperature sensitive goods, such as blood, plasma, medical supplies, food products, or other cold chain materials, in a container. The container may then be placed within a temperature-controlled case that includes a corresponding built in power source to provide active refrigeration and temperature control for the temperature sensitive goods maintained therein. While functional, the resulting container system is bulky and excessively heavy to be carried around, such as by a medic in a battlefield.
The shipment of temperature sensitive goods is extremely difficult when the shipping container itself is not independently temperature controlled. If it is desirable to only maintain the temperature sensitive goods at a nominally cooled temperature, relative to the ambient temperature, then a common practice is to pack ice or dry ice around the temperature sensitive goods. When using ice, the container hopefully maintains the temperature sufficiently cool until the goods are desired to be used. Unfortunately, the goods tend to significantly increase in temperature as the ice melts, especially in warm environments, likely spoiling the goods. Also, different regions within the container tends to have substantially different temperatures, further complicating the transportation of temperature sensitive goods. Moreover, the temperature of the goods during the melting of the ice tends to vary, likely in a range in excess of that which is desired to maintain the integrity of the goods, especially goods where the temperature needs to be maintained within a relatively narrow range to assure quality, although frozen is not desirable.
In other situations, it is desirable to ship the temperature sensitive goods at a temperature above the anticipated ambient temperature, such as in artic regions or during the winter. In this case, the temperature sensitive goods are placed into the container at a warm temperature relative to the ambient temperature. The goods are shipped to the destination with a hope that the shipping time is sufficiently short in duration before the temperature sensitive goods become too cold as the heat inside the container escapes.
The foregoing and other objectives, features, and advantages of the invention may be more readily understood upon consideration of the following detailed description of the invention, taken in conjunction with the accompanying drawings.
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The thermal isolation chamber panel 400 is placed within the protective chamber 300 which is placed within the insulated thermal chamber 200 which is placed within the cardboard box 100. Alternatively, the thermal isolation chamber panel 400 is placed within the insulated thermal chamber 200 which is placed within a hard plastic high density polyethylene case or a roto-molded polypropylene based case.
In the case of blood, vaccines, food, breast milk, metals, and/or other products for transportation, a cold chain process is employed. The blood cold chain (including or alternatively other products) is a systematic process for the safe storage and transportation of blood from its collection from the donor to its administration to a patient who requires transfusion. It is referred to as a ‘cold chain’ because blood, being a biological substance, must be kept cold in order to reduce bacterial contamination and to prolong its life. Whole blood is warm when collected but must be cooled down to 4° C. and kept at this temperature until the point of transfusion. The purpose of a transfusion is to provide blood components that improve the hematological status of the patient. Whole blood can be used to yield various blood components. Most blood banks are able to separate red cells and plasma components. Some are able to prepare other products, such as platelet concentrates and cryoprecipitate. These products are often referred to as “wet products”. Other plasma products, generally referred to as plasma derivatives, can be extracted from plasma by a pharmaceutical process called plasma fractionation. All of these products have a specific benefit to the patient. However, in order for the blood component or plasma derivative to provide that benefit, it must be transfused in a viable state. Blood must be stored and transported in equipment that meets defined standards of performance, and by staff who correctly follow established procedures at all times.
One of the key aspects to such blood cold chain is the packing and transportation required to move blood components safely through the blood cold chain, and in particular, the packing for safely transporting the blood to the patient, which may be in a remote location, using a portable transportation box. By way of example, this may include a medic in a forward military location, a paramedic, and/or a fire fighter responding to a car wreck, who is carrying the blood in the portable transportation box for emergency usage. The blood should be maintained at a temperature range between 38 degrees F. to 40 degrees F., for 12 to 120 hours, for increased effectiveness.
In a harsh environment, the cardboard box 100 tends to get wet and soggy, substantially degrading its structural integrity. Also, the cardboard box 100 has a substantial likelihood of being damaged as a result of shipping. With a decreased structural integrity of the cardboard box 100, the insulated thermal chamber 200 tends to be prone to puncture. Upon being punctured, the insulated thermal chamber 200 loses its vacuum seal thus compromising its insulative characteristics. In the case of a hard plastic box made from high density polythene, it tends to be brittle with relatively low impact resistance, which again the insulated thermal chamber 200 tends to be prone to puncture. Roto-molded boxes tend to be strong but are excessively heavy and bulky.
With such boxes made from cardboard and high density polythene being unsuitable for hard environments to protect the integrity of the insulated thermal chamber 200, a different approach is desirable that provides sufficient impact resistance, relatively thin material suitable for being carried by a medic, provides sufficient puncture resistance, sufficiently flexible to absorb impact, strong enough to sufficiently resist compressive impacts, and sufficiently smooth so that the insulated thermal chamber 200 is not abraded, all of which provide protection to the insulated thermal chamber 200 to protect the blood therein in a cold chain environment.
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By way of example, the woven thermoplastic composite material may start out a series of polypropylene (PP) films that form a tape yarn within a polymer matrix—for composite processing—before being woven into fabric. This is then pressed under heat and pressure to form a single piece approximately 0.005 inch (0.13 mm) that weighs just 0.02 lbs/sq.ft (0.11 kg/sq·m). Multiple layers are added depending on the desired thickness. The multi-layers are melted together. From there, the sheet can be formed into a variety of shapes using heat and pressure, depending on the mold. The end result contains no fragment-producing glass, unlike carbon fiber or various glass type structures, has high impact resistance and retains strength from around +180 degrees F. down to −40 degrees F.
By way of example, the self-reinforced composite materials may include a density (kg/m3) of greater than 800, and more preferably greater than 900. By way of example, the self-reinforced composite materials may include a tensile modulus (GPa) between 3 and 35, and more preferably between 3 and 30. By way of example, the self-reinforced composite materials may include a tensile strength (MPa) of greater than 100, and more preferably greater than 125, and less than 500, and more preferably less than 400. By way of example, the self-reinforced composite materials may include an edgewise notched Izod impact strength at 20 degrees C. (J/m) of greater than 100 and less than 6000, and more preferably greater than 1250 and less than 5000. Also, hybrid SRC composite materials together with carbon or ultra-high molecular weight polyethylene (e.g., 3 to 8 million amu) may be used. By way of example, he UHMWPE powder grade GUR 4120 (molecular weight of approximately 5.0×106 g/mol) may be used to produce an isotropic part of the multilayered sample. The powder may be heated up to 180° C. at a pressure of 25 MPa in a stainless-steel mold to produce 80×10×2 mm3 rectangular samples, with fibers having an average diameter of 15 μm (e.g., 10-20 μm) and a linear density of 220 Dtex (e.g., 150-300 Dtex).
Rather than a case constructed from brittle material that tends to puncture the vacuum packed insulative material, a case constructed from glass based carbon fiber material that tends to puncture the vacuum packed insulative material, or otherwise a structurally collapsible cardboard that tends to degrade making the vacuum packed insulative material readily subject to damage, preferably a case constructed from a self-reinforced polymeric material is used which provides sufficient impact resistance, relatively thin material suitable for being carried by a medic, provides sufficient puncture resistance, sufficiently flexible to absorb impact, strong enough to sufficiently resist compressive impacts, and sufficiently smooth so that the insulated thermal chamber is not abraded during usage.
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The overall system, that includes the thermal isolation chamber panel 400 placed within the protective chamber 300, if desired, placed within the insulated thermal chamber 200, placed within the self-reinforced polymeric material container may be used to ship blood test samples or other biologic materials, such as CV-19 samples, which reduces the likelihood of damage during transit.
The overall system, that includes the thermal isolation chamber panel 400 placed within the protective chamber 300, if desired, placed within the insulated thermal chamber 200, placed within the self-reinforced polymeric material container may be used to store breast milk shortly after pumping which reduces the likelihood of spoilage during the day.
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In another embodiment, the container is both sufficiently rugged and lightweight to be suitable for being delivered from a source location to a destination location using a flying vehicle, such as a drone with multiple rotating propellers. The container may be secured to the drone in a manner such that the container is not readily detachable, so that it will not be likely to fall during the flight from the source location to the destination location. The container should include a lid on the container, and in particular, the container should include a lid that is secured in some fashion, such as using a locking mechanism.
The terms and expressions which have been employed in the foregoing specification are used therein as terms of description and not of limitation, and there is no intention, in the use of such terms and expressions, of excluding equivalents of the features shown and described or portions thereof, it being recognized that the scope of the invention is defined and limited only by the claims which follow.
This application claims the benefit of U.S. Provisional Patent Application Ser. No. 63/093,563 filed Oct. 19, 2020.
Number | Date | Country | |
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63093563 | Oct 2020 | US |