1. Field of the Invention
The invention relates to a container with a flexible wall and with at least one emptying tube that projects through a wall aperture into the container interior surrounded by the flexible wall, the free end of which emptying tube has an emptying opening that can be set in its position in the vertical direction to different emptying heights.
2. Description of the Related Art
WO 2011/094534 A2 discloses a container with a flexible wall that has a container interior into which the free end of an emptying tube projects through a wall aperture. The free end of the emptying tube has an emptying opening that is adjustable to different emptying heights.
In this regard, it is disadvantageous that the emptying tube projects into the container interior through a rotation adapter arranged within a wall aperture on a side wall and that it is necessary for the free end to be angled at 90° within the container interior. The emptying tube is arranged so as to be rotatable within the rotation adapter, which allows the emptying height to be adjusted by means of a rotation. If the container is designed as a cylinder and the angled free end of the emptying tube is placed close to the wall, it can come into contact with the wall, thereby preventing it from rotating 360°. When installed proximate to the middle of the container, the free end can come into contact with a stirrer located in the middle of the container. It is also disadvantageous that the emptying tube, which is arranged so as to be rotatable within the adapter, is very difficult to seal. Because of the relatively high costs associated with this, the disclosed container is therefore not suitable as a cost-effective single-use container.
The present invention seeks to solve the problem of providing a container with a flexible wall, having an emptying tube, whereby the emptying opening is to be adjustable to different emptying heights. With regard to the container, the emptying tube is therefore to be designed to be secure and cost-effective, such that the container, in particular, is suitable for use as a single-use container.
This problem is solved by a container with a flexible wall and with at least one emptying tube that projects through a wall aperture into the container interior surrounded by the flexible wall. The free end of the emptying tube has an emptying opening that can be set in its position in the vertical direction to different emptying heights. The container is characterized in that an adapter piece, in which the emptying tube is held in a longitudinally displaceable manner, is arranged in the wall aperture and in that a portion of the emptying tube is surrounded by a flexible sheath which is connected at a first end to the emptying tube and at its second end, which is remote from the first end, to the wall or the adapter piece.
The flexible sheath with the second end that makes a sealed connection to the wall of the flexible container or to the adapter piece, and with the second end that makes a sealed connection with the emptying tube, ensures straightforward and secure sealing without contamination risk. The flexible sheath forms a sterile barrier. The secure sealing provided by the flexible sheath makes it relatively easy, such as by means of O ring seals, to position the emptying tube in the adapter piece in such a manner that the emptying tube remains displaceable and fastened. The adapter piece can therefore also be designed in a straightforward and cost-effective manner. In particular, this makes the container suitable as a cost-effective and secure single-use container. The emptying tube that projects into the container interior can project into the container interior vertically, from above, or diagonally, from the side, for example.
Instead of the flexible sheath, O ring seals or similar sealing elements can also be used, especially those suitable for use in glass or stainless steel containers.
According to one embodiment of the invention, the flexible sheath is designed as a hose or tubular film. This forms an especially cost-effective sterile barrier. The flexible sheath can also be designed as a bellows hose.
According to another embodiment of the invention, the flexible sheath is arranged within the container interior. The arrangement within the container interior makes it possible to employ a relatively thin sheath design since within the container interior it is protected by the container walls.
The emptying tube may be designed as an extensible telescopic tube. This also enables drainage proximate to the container base. However, it is also possible to design the emptying tube as a flexible hose.
One or more hose guides to guide the free end of the emptying tube may be arranged on the wall within the container interior. The hose guide prevents the flexible hose from being laterally displaced, such as by flow dynamics caused by a stirrer.
According to another embodiment, a filter, such as a depth filter, is placed upstream of the emptying opening. This allows for retention of specific particles.
The end of the emptying tube facing away from the emptying opening may have one part of a sterile connector. It is also possible to replace the aforementioned sterile connector with a weldable hose for sterile connection of two hoses.
A second emptying tube may project into the container interior. The second emptying tube can be arranged on the opposite side of the container interior from the first emptying tube.
The container with emptying tube may be employed as a single-use container.
Additional features and advantages of the invention are evident from the following special description and the drawings.
A container 1 with a flexible wall 2, such as for a bioreactor, essentially consisting of a container interior 3, an emptying tube 4 and a flexible sheath 5.
According to the exemplary embodiment from
According to the exemplary embodiment from
According to the exemplary embodiment from
According to the exemplary embodiment from
According to the exemplary embodiments in
The container 1 is intended to be employed as a single-use container and, in particular, can be used as a container with a flexible wall for a bioreactor (not shown).
The end of the emptying tube 4 facing away from the emptying opening 13 has a first part 18 of a two-part sterile connector 19.
Of course, the embodiments discussed in the specific description and shown in the figures are merely illustrative exemplary embodiments of the present invention. In light of this disclosure, a person skilled in the art is given a wide range of possible variations.
1 Container
2 Flexible wall
3 Container interior
4, 4′, 4″ Emptying tube
5 Flexible sheath
6 Top of 1
7 Wall aperture
8 Adapter piece
10 Second end of 5
11 First end of 5
12 Free end of 4
13, 13′ Emptying opening
14 Emptying height
15 Second tube of 4′
16 Base of 1
17 Filter
18 First part of 19
19 Sterile connector
20 Hose guide
Number | Date | Country | Kind |
---|---|---|---|
10 2013 109 819.3 | Sep 2013 | DE | national |
Filing Document | Filing Date | Country | Kind |
---|---|---|---|
PCT/EP2014/067582 | 8/18/2014 | WO | 00 |