The invention relates to containers, and more particularly relates to a container with an embedded structure.
According to the development of biomedical technology, biotechnology has been widely used in the fields of agriculture, food industry and medicine, and biotechnology includes the technologies of genetic engineering, cell culture and tissue culture. Among the technologies, cell culture is one of the basic implementation technologies for biomedical related research work. A common cell culture technology places cells in a multi-well microplate and grows them in a static culture method under sterile, proper temperature and nutrient conditions. About a week later, each of the cells will grow into a colony to achieve an object of proliferation.
In addition, in order to ensure that the cells are cultured in an environment free from external interference, the multi-well microplate is usually covered with an outer cover. However, due to the conventional combination between the multi-well microplate and the outer cover is mainly achieved by means of screw connection between a screw and a screw hole, the use of such method shows that the above-mentioned conventional structure is inconvenient for closing or opening the outer cover. Furthermore, if a user does not securely lock the outer cover, an inside of the multi-well microplate will be connected to the outside, besides the possibility of leakage, it may also have an adverse effect on the growth of cells, and therefore experimental errors are increased.
Therefore, a main object of the invention is to provide a container with an embedded structure, which has a simplified structure, in addition to being convenient to assemble and disassemble, an accommodating space is formed between two plates, while ensuring the accommodating space is kept in a liquid-tight state to avoid leakage.
Another object of the invention is to provide a container with an embedded structure capable of being used for cell culture and applied to biomedical cell detection.
Therefore, in order to achieve the above-mentioned objects, the invention provides a container with an embedded structure comprising: a first plate with a first plate body, a first end surface located on one side of the first plate body; a second plate with a second plate body, a second end surface opposite to the first end surface and located on one side of the second plate body, a flexible protrusion being annularly protruded on the second end surface and abutting against the first plate to form an accommodating space between the first end surface, the second end surface, and the protrusion for a fluid to flow in the accommodating space, and the accommodating space having an accommodating height between the first end surface and the second end surface; and a shape of a portion of a free end of the protrusion abutting the first end surface being deformed.
Wherein the first plate further includes a concave portion complementarily embedded with the protrusion, and recessed with a predetermined depth from the first end surface toward an inner direction of the first plate body.
In one embodiment of the invention, the protrusion further includes a first convex body inserted in the concave portion, a free end of the first convex body abuts against a bottom surface of the concave portion, a height of the first convex body protruding outside of the second end surface is greater than a depth of the concave portion, and a portion of the first convex body exposed outside of the concave portion constitutes the accommodating height. With the aforementioned structure, in addition to facilitating simple and rapid assembly or separation between the first and second plates, structural corresponding design of the protrusion and the concave portion is capable of forming the accommodating space between the first and second plates.
In one embodiment of the invention, the protrusion further includes a first convex body inserted in the concave portion, and a second convex body disposed on one side of the first convex body, a height of the first convex body protruding outside of the second end surface is greater than a height of the second convex body protruding outside of the second end surface, and a stopping distance between the free end of the first convex body and a free end of the second convex body is smaller than the depth of the concave portion, so that the free end of the second convex body abuts on the first end surface, and a height of the second convex body constitutes the accommodating height. With the aforementioned structure, in addition to facilitating simple and rapid assembly or separation between the first and second plates, structural corresponding design of the protrusion and the concave portion is capable of forming the accommodating space between the first and second plates.
In one embodiment of the invention, the protrusion further includes a first convex body inserted in the concave portion, a height of the convex body protruding from the second end surface is not greater than a depth of the concave portion; the first plate further includes a groove located on the first end surface and surrounded by the concave portion, a predetermined groove depth is recessed from the first end surface toward the inner direction of the first plate body, and the groove depth of the groove constitutes the accommodating height. With the aforementioned structure, in addition to facilitating simple and rapid assembly or separation between the first and second plates, structural corresponding design of the groove is capable of forming the accommodating space between the first and second plates.
In one embodiment of the invention, the first plate further includes a groove located on the first end surface and surrounded by the concave portion, a predetermined groove depth is recessed from the first end surface toward the inner direction of the first plate body; the protrusion further includes a columned first convex body inserted in the concave portion, and a shouldered second convex body with a predetermined thickness disposed on one side of the first convex body, a height of the first convex body protruding outside of the second end surface is greater than a height of the second convex body protruding outside of the second end surface, and a stopping distance between the free end of the first convex body and the free end of the second convex body is smaller than the depth of the concave portion, so that the free end of the second convex body abuts on the first end surface, and disposes between the free end of the first convex body and the first end surface, and is used to abut on the bottom surface of the concave portion, and a sum of the groove depth of the groove and the height of the shouldered second convex body constitutes the accommodating height. With the aforementioned structure, in addition to facilitating simple and rapid assembly or separation between the first and second plates, structural corresponding design of the protrusion, the concave portion and the groove is capable of forming the accommodating space between the first and second plates.
Further, in each of the above embodiments, an axial sectional width of the protrusion along its own annular center is not less than an axial sectional width of the concave portion along its own annular center, flexible physical properties of the protrusion allow the protrusion to squeeze into the concave portion with a slight deformation to achieve a tight embedding state, and to be capable of increasing a contact area between the protrusion and the concave portion, thereby enhancing a bonding strength.
In another embodiment, further including a third plate; the third plate has a third end surface, the second plate has a fourth end surface located on another side of the second plate body and opposite to the second end surface, and the third end surface of the third plate is attached with the fourth end surface of the second plate, so that the second plate is sandwiched and pressed tightly between the first plate and the third plate. Thereby, a portion of the protrusion abutting on the first end surface is deformed due to being pressed to ensure its liquid tightness and avoid the problem of leakage.
Wherein the axial sectional width of the protrusion along its own annular center is not greater than the axial sectional width of the concave portion along its own annular center.
In order to achieve the above disclosed objects, the invention also provides a container with an embedded structure comprising: a first plate with a first plate body, a first end surface located on one side of the first plate body; and a flexible second plate with a second plate body, a second end surface opposite to the first end surface and located on one side of the second plate body, a sleeve portion annularly protruded on the second end surface to sleeve on the first plate to achieve a tightly connected state between the first plate and the sleeve portion in order to form an accommodating space between the first end surface, the second end surface, and the sleeve portion for a fluid to flow in the accommodating space, and the accommodating space has an accommodating height between the first end surface and the second end surface.
Wherein the second plate is made of flexible material.
Wherein the first plate further includes a protruding portion protruding on the first end surface, an outer diameter of the protruding portion is greater than an inner diameter of the sleeve portion, when an inner side surface of the sleeve portion is sleeved on a peripheral side of the protruding portion, the second plate is deformed to change the inner diameter of the sleeve portion. Thereby, facilitating simple and rapid assembly or separation between the first and second plates.
In one embodiment of the invention, a height of the protruding portion protruding from the first end surface is smaller than a height of the sleeve portion protruding from the second end surface, and an accommodating space is formed between the first and second plates.
In one embodiment of the invention, the first plate further includes a groove located on the protruding portion, a predetermined groove depth is recessed from the first end surface toward the inner direction of the first plate body, and a groove depth of the groove constitutes the accommodating height.
In one embodiment of the invention, the sleeve portion further includes a first sleeve body sleeved on the peripheral side of the protruding portion, and a second sleeve body provided on one side of the first sleeve body, a height of the first sleeve body protruding outside of the second end surface is greater than a height of the second sleeve body protruding outside of the second end surface, and a stopping distance between a free end of the first sleeve body and a free end of the second sleeve body is smaller than the depth of the concave portion, so that the free end of the second sleeve body abuts on the protruding portion, and a height of the second sleeve body constitutes the accommodating height.
In one embodiment of the invention, the first plate further includes a groove located on the protruding portion, a predetermined groove depth is recessed from the first end surface toward the inner direction of the first plate body; the sleeve portion further includes a first sleeve body sleeved on the peripheral side of the protruding portion, and a second sleeve body provided on one side of the first sleeve body, a height of the first sleeve body protruding outside of the second end surface is greater than a height of the second sleeve body protruding outside of the second end surface, and a stopping distance between the free end of the first sleeve body and the free end of the second sleeve body is smaller than the depth of the concave portion, so that the free end of the second sleeve body abuts on the protruding portion, and a sum of the groove depth of the groove and the height of the second sleeve body constitutes the accommodating height.
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The first plate 10 is made of hard plastic material, and the first plate 10 has a first plate body 11 and a first end surface 12 located on one side of the first plate body 11. Wherein the first plate 10 is made by injection molding, and then further micro-engraving is used to cut out required lines and contour. Of course, the first plate 10 can also be made by precise one-piece molding without the need for secondary engraving.
The second plate 20 is a flexible body made of silicone rubber material, the second plate 20 has a second plate body 21, a second end surface 22 opposite to the first end surface 12 and located on one side of the second plate body 21, a flexible protrusion 23 annularly protruded on the second end surface 22, and a fourth end surface 24 located on another side of the second plate body 21 and opposite to the second end surface 22.
The third plate 30 is made of hard plastic material, and the third plate 30 has a third end surface 31 that is attached to the fourth end surface 24 oppositely. The first plate 10 and the third plate 30 can be connected through a butting structure, so that the second plate 20 is sandwiched and forced to be located between the first plate 10 and the third plate 30, and the second plate 20 is subjected to a pressing force. Wherein the butting structure can be but not limited to snap components.
With composition of the above-mentioned components, the container with the embedded structure is capable of making combination of the first plate 10 and the second plate 20 in a tightly connected state. As shown in
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In the second embodiment, the first plate 10a further includes a concave portion 13a that is complementarily embedded with a protrusion 23a, and a predetermined depth D1a is recessed from a first end surface 12a toward an inner direction of a first plate body 11a. Furthermore, the protrusion 23a further includes a first convex body 231a inserted into the concave portion 13a. During a process of embedding the protrusion 23a into the concave portion 13a, a free end of the first convex body 231a reaches into the concave portion 13a until the free end abuts on a bottom surface of the concave portion 13a, so that a portion of the first convex body 231a is inserted into the concave portion 13a, thereby providing a quick and convenient positioning method. Since a height H2a of the first convex body 231a protruding from a second end surface 22a is greater than the depth D1a of the concave portion 13a, the first convex body 231a will not be completely submerged in the concave portion 13a, and a portion of the first convex body 231a exposed outside of the concave portion 13a constitutes an accommodating height H1a. At the same time, in order to make the first convex body 231a and the concave portion 13a fit tightly to achieve an air-tight state and avoid fluid leakage, an axial sectional width W1a of the protrusion 23a along its own annular center is further made equal to an axial sectional width W2a of the concave portion 13a along its own annular center, and flexible physical properties of the protrusion 23a allow the first convex body 231a to be slightly deformed to squeeze into the concave portion 13a to achieve a tightly embedded state. In other embodiments, the axial sectional width W1a of the protrusion 23a along its own annular center can be smaller than the axial sectional width W2a of the concave portion 13a along its own annular center, and only the free end of the first convex body 231a is used to press against the bottom surface of the concave portion 13a to achieve an air-tight effect.
Wherein a cross-sectional shape of the free end of the first convex body 231a can be, but is not limited to, any one of a group consisting of arc, tapered, round, and ellipse.
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The first plate 10e is made of hard plastic material, and the first plate 10e has a first plate body 11e, a first end surface 12e located on one side of the first plate body 11e, and a concave portion 13e with a predetermined depth D1e recessed from the first end surface 12e toward an inner direction of the first plate body 11e. Wherein the first plate 10e is made by injection molding, and then further micro-engraving is used to cut out required lines and contour. Of course, the first plate 10e can also be made by precise one-piece molding without the need for secondary engraving.
The second plate 20e is a flexible body made of silicone rubber material, and the second plate 20e has a second plate body 21e, a second end surface 22e opposite to the first end surface 12e and located on one side of the second plate body 21e, and a flexible protrusion 23e annularly protruded on the second end surface 22e for complementarily embedding with the concave portion 13e, and the protrusion 23e is capable of reliably sealing a gap between the first plate 10e and the second plate 20e to completely prevent leakage of material in the accommodating space 40e.
In a specific implementing method, the protrusion 23e further includes a first convex body 231e inserted into the concave portion 13e. During a process of embedding the protrusion 23e into the concave portion 13e, a free end of the first convex body 231e reaches into the concave portion 13e until the free end abuts on a bottom surface of the concave portion 13e, so that a portion of the first convex body 231e is inserted into the concave portion 13e, thereby providing a quick and convenient positioning method. Since a height H2e of the first convex body 231e protruding from the second end surface 22e is greater than the depth D1e of the concave portion 13e, the first convex body 231e will not be completely submerged in the concave portion 13e, and a portion of the first convex body 231e exposed outside of the concave portion 13e constitutes an accommodating height H1e. At the same time, in order to make the first convex body 231e and the concave portion 13e fit tightly to achieve an air-tight state and avoid fluid leakage, an axial sectional width W1e of the protrusion 23e along its own annular center is further made not less than an axial sectional width W2e of the concave portion 13e along its own annular center, and flexible physical properties of the protrusion 23e allow the first convex body 231e to be slightly deformed to squeeze into the concave portion 13e to achieve a tightly embedded state.
Wherein a cross-sectional shape of the free end of the first convex body 231e can be, but is not limited to, any one of a group consisting of arc, tapered, round, and ellipse.
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The first plate 10j is made of hard plastic material, and the first plate 10j has a first plate body 11j, a first end surface 12j located on one side of the first plate body 11j, and a protruding portion 15j protruded on the first end surface 12j. Wherein the first plate 10j is made by injection molding, and then further micro-engraving is used to cut out required lines and contour. Of course, the first plate 10j can also be made by precise one-piece molding without the need for secondary engraving.
The second plate 20j is a flexible body made of silicone rubber material, and the second plate 20j has a second plate body 21j, a second end surface 22j opposite to the first end surface 12j and located on one side of the second plate body 21j, and a sleeve portion 25j annularly protruded on the second end surface 22j to sleeve on the protruding portion 15j of the first plate 10j to achieve a tightly connected state between the first plate 10j and the sleeve portion 25j in order to reliably seal a gap between the first plate 10j and the second plate 20j to completely prevent leakage of material in the accommodating space 40j.
In a specific implementing method, in order to provide a quick and convenient positioning method between the protruding portion 15j and the sleeve portion 25j, an outer diameter D4j of the protruding portion 15j is greater than an inner diameter D5j of the sleeve portion 25j. During an assembly process, due to compressible, deformable and flexible elasticity of silicone rubber material, through an external acting force, the second plate 20j is deformed to change the inner diameter D5j of the sleeve portion 25j, thereby an inner side surface of the sleeve portion 25j is sleeved on a peripheral side of the protruding portion 15j, and finally the protruding portion 15j and the sleeve portion 25j are tightly fitted to achieve an airtight state to avoid fluid leakage.
Furthermore, a height H4j of the protruding portion 15j protruding from the first end surface 12j is smaller than a height H5j of the sleeve portion 25j protruding from the second end surface 22j, so that the accommodating space 40j is formed between the first end surface 12j, the second end surface 22j and the sleeve portion 25j for a fluid to flow in the accommodating space 40j, and the accommodating space 40j has an accommodating height H1j between the first end surface 12j and the second end surface 22j, that is, a difference between the height H4j of the protruding portion 15j and the height H5j of the sleeve portion 25j is the accommodating height H1j.
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In a process of sleeving the sleeve portion 25l on the protruding portion 15l, in order to provide a quick and convenient positioning method between the sleeve portion 25l and the protruding portion 15l, an inner wall surface of a portion of the first sleeve body 251l protruding and exposing from the second sleeve body 252l first sleeves against the peripheral side of the protruding portion 15l, and flexible physical properties of a protrusion 231 allow the free end of the second sleeve body 252l to be slightly deformed to abut and stop on the first end surface 12c to achieve a double airtight embedding state.
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It is to be understood that the above description is only preferred embodiments of the present invention and is not used to limit the present invention, and changes in accordance with the concepts of the present invention may be made without departing from the spirit of the present invention, for example, the equivalent effects produced by various transformations, variations, modifications and applications made to the configurations or arrangements shall still fall within the scope covered by the appended claims of the present invention.
Filing Document | Filing Date | Country | Kind |
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PCT/CN2019/075810 | 2/22/2019 | WO | 00 |