Claims
- 1. A method for mollifying the irritant effect of an anti-aging agent, comprising incorporating in a cosmetic or dermatological composition, comprising at least one anti-aging active agent having an irritant effect and a cosmetically or dermatologically acceptable medium consisting of at least one of an oily or fatty solvent and an aqueous solvent, said oily or fatty solvent selected from the group consisting of oily or fatty alcohols, ethers, hydrocarbons and mixtures thereof, a mollifying agent which is a ceramide of formula (I): ##STR5## wherein A is ##STR6## R.sub.1 is a saturated or unsaturated, linear or branched C.sub.10 to C.sub.26 alkyl group;
- R.sub.2 is a saturated or unsaturated, linear or branched C.sub.12 to C.sub.32 alkyl group;
- R.sub.3 is H or --CO--CHOH--R.sub.2 ; and
- n is 0 or 1.
- 2. The method of claim 1, wherein said mollifying agent is selected from the group consisting of N-oleoyldihydrosphingosine, N-stearoylphytosphingosine, N-(.alpha.-hydroxybehenoyl)dihydrosphingosine, and N-(.alpha.-hydroxypalmitoyl)dihydrosphingosine.
- 3. The method of claim 1, wherein said anti-aging active agent is selected from the group consisting of .alpha.-hydroxy acids, .beta.-hydroxy acids, .alpha.-keto acids, .beta.-keto acids, retinoids, anthraline, anthranoids, peroxides, monoxidil, capsaicin, lithium and zinc salts, antimetabolites and vitamins.
- 4. The method of claim 1, wherein said anti-aging active agent is selected from the group consisting of .alpha.-hydroxy acids, 5-n-octanoylsalicylic acid, and salicylic acid.
- 5. The method of claim 1, wherein said mollifying agent is present in said composition in a mollifying agent/anti-aging active agent weight ratio ranging from 0.0001:1 to 100,000:1.
- 6. The method of claim 1, wherein said composition is in the form of a lotion, an aqueous gel, a serum, an emulsion, or a dispersion of lipid vesicles.
- 7. The method of claim 1, wherein said composition further comprises a lipophilic or hydrophilic active agent different from said anti-aging active agent.
- 8. A method for mollifying the irritant effect of an anti-aging agent, comprising incorporating in a cosmetic or dermatological composition, comprising at least one anti-aging active agent having an irritant effect and a cosmetically or dermatologically acceptable medium, a mollifying agent which is a ceramide of formula (I): ##STR7## wherein A is ##STR8## R.sub.1 is a saturated or unsaturated, linear or branched C.sub.10 to C.sub.26 alkyl group;
- R.sub.2 is a saturated or unsaturated, linear or branched C.sub.12 to C.sub.32 alkyl group;
- R.sub.3 is H or --CO--CHOH--R.sub.2 ; and
- n is 0 or 1,
- the mollifying agent being the only component present to remove the irritant effect.
Priority Claims (1)
Number |
Date |
Country |
Kind |
94 00173 |
Jan 1994 |
FRX |
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Parent Case Info
This is a Continuation of application Ser. No. 08/366,760 filed on Dec. 30, 1994, now U.S. Pat. No. 5,589,178.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
5368857 |
Corcoran et al. |
Nov 1994 |
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5411734 |
Vargas et al. |
May 1995 |
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5443840 |
Morancais et al. |
Aug 1995 |
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Continuations (1)
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Number |
Date |
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Parent |
366760 |
Dec 1994 |
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