CRANIOMANDIBULAR DISORDERS: LONG TERM OUTCOME STUDY

Information

  • Research Project
  • 3462198
  • ApplicationId
    3462198
  • Core Project Number
    R29DE008668
  • Full Project Number
    1R29DE008668-01A2
  • Serial Number
    8668
  • FOA Number
  • Sub Project Id
  • Project Start Date
    9/30/1991 - 32 years ago
  • Project End Date
    9/29/1996 - 27 years ago
  • Program Officer Name
  • Budget Start Date
    9/30/1991 - 32 years ago
  • Budget End Date
    9/29/1992 - 31 years ago
  • Fiscal Year
    1991
  • Support Year
    1
  • Suffix
    A2
  • Award Notice Date
    1/1/2999 - 975 years from now
Organizations

CRANIOMANDIBULAR DISORDERS: LONG TERM OUTCOME STUDY

Treatment for craniomandibular disorders varies between conservative and surgical interventions. Longitudinal studies have shown positive outcomes with either intervention. However, due to the lack of controlled epidemiological research in the field, the relative long-term efficacy of the different treatments has not been fully established. Also, prior studies especially with conservative intervention have been composed of heterogenous diagnostic groups, so conclusions about specific diagnostic groups is not possible. The aims of this study are to complete a 3-year longitudinal outcome study of 150 consecutive female patients to 1) determine if the progression of TMJ ID without reduction can be halted or reversed wiith standardized conservative treatment versus surgical treatment, 2) deterinine what demographic, occlusal, behavioral or psychosocial factors affect outcome with different treatments. Pre-treatment data to be collected includes data to calculate the Cranio-mandibular Index (CMI), Symptom Severity Index (SSI), Helkimo's Clinical Dysfunction (Di) and Anamnestic Indices (Ai) indices that measure the objective and subjective severity of pain and dysfunction. Also, the Oral Habit Index (OHI), the Occlusal Dysharmony Index (ODI), the Illness Impact Index (III) and the West Haven-Yale Multidimensional Pain Inventory (MPI) will be utilized to assess the objective and subjective indicators of parafunctional habits, occlusal stability and the impact the disorder has on the patients' life. In addition, subjects will have specific TM joint diagnosis by using MRI and tomography. Subject selection is standardized with specific inclusion criteria. Blue Cross Blue Shield and other third part carriers have agreed to underwrite the cost of the imaging and interventions used in this study. The progression or regression of signs and symptoms of TMJ ID without reduction will be determined by the change in CMI, Di, Ai and SSI. Post-treatment radiographic status will be detemined by the change in the MRIs and tomograms. The relationship that oral parafunctional habits, occlusal disharmony, illness impact and psychosocial factors or a combination of these factors have wlth this progression or regression will be determined. The results will be used to help predict the consequences of nonsurgical treatment versus surgical treatment and determining what factors influence this process.

IC Name
NATIONAL INSTITUTE OF DENTAL &CRANIOFACIAL RESEARCH
  • Activity
    R29
  • Administering IC
    DE
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    121
  • Ed Inst. Type
    SCHOOLS OF DENTISTRY/ORAL HYGN
  • Funding ICs
  • Funding Mechanism
  • Study Section
    OBM
  • Study Section Name
    Oral Biology and Medicine Study Section
  • Organization Name
    UNIVERSITY OF MINNESOTA TWIN CITIES
  • Organization Department
  • Organization DUNS
    168559177
  • Organization City
    MINNEAPOLIS
  • Organization State
    MN
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    554552070
  • Organization District
    UNITED STATES