Claims
- 1. A method for providing creatine to an animal, comprising:
receiving a creatine ester by the animal, wherein the creatine ester is suitable for being modified by the animal to form creatine.
- 2. The method as described in claim 1, wherein the creatine ester is suitable for being formed in a solid form capable of being ingested by the animal.
- 3. The method as described in claim 2, wherein the solid form includes the creatine ester and at least one of dextrose and phosphate.
- 4. The method as described in claim 2, wherein the solid form is configured as at least one of a tablet and a capsule.
- 5. The method as described in claim 1, wherein the creatine ester is suitable for liquid delivery.
- 6. The method as described in claim 5, wherein the creatine ester includes at least one of an aqueous solution and emulsion.
- 7. The method as described in claim 1, wherein the creatine ester includes at least one of creatine ethyl ester, creatine benzyl ester, creatine phosphoester, monocreatine glycerol, t-butyl creatine ester, dicreatine glycerol and tricreatine glycerol.
- 8. The method as described in claim 1, wherein the creatine ester is received by the animal, the creatine ester is modified by the animal into creatine and an alcohol.
- 9. The method as described in claim 8, wherein the creatine ester is modified by the animal into creatine and alcohol by an esterase.
- 10. The method as described in claim 8, wherein the creatine ester is modified by at least one of an intestinal lumen, epithelial cell and blood of the animal into creatine.
- 11. The method as described in claim 1, further comprising forming a creatine ester, wherein an acid moiety of creatine is modified to provide an ester bond.
- 12. The method as described in claim 1, wherein the animal includes a human and livestock.
- 13. A food supplement, comprising:
a creatine ester suitable for being modified by an animal to form creatine.
- 14. The food supplement as described in claim 13, wherein the creatine ester is suitable for being formed in a solid form capable of being ingested by the animal.
- 15. The food supplement as described in claim 14, wherein the solid form includes the creatine ester and at least one of dextrose and phosphate.
- 16. The food supplement as described in claim 14, wherein the solid form is configured as at least one of a tablet and a capsule.
- 17. The food supplement as described in claim 13, wherein the creatine ester is suitable for liquid delivery.
- 18. The food supplement as described in claim 17, wherein the creatine ester includes at least one of an aqueous solution and emulsion.
- 19. The food supplement as described in claim 13, wherein the creatine ester includes at least one of creatine ethyl ester, creatine benzyl ester, creatine phosphoester, monocreatine glycerol, t-butyl creatine ester, dicreatine glycerol and tricreatine glycerol.
- 20. The food supplement as described in claim 13, wherein the creatine ester is received by the animal, the creatine ester is modified by the animal into creatine and an alcohol.
- 21. The food supplement as described in claim 20, wherein the creatine ester is modified by the animal into creatine and alcohol by an esterase.
- 22. The food supplement as described in claim 20, wherein the creatine ester is modified by at least one of an intestinal lumen, epithelial cell and blood of the animal into creatine.
- 23. The food supplement as described in claim 13, further comprising forming a creatine ester, wherein an acid moiety of creatine is modified to provide an ester bond.
- 24. The food supplement as described in claim 13, wherein the animal includes at least one of human and livestock.
- 25. A method for providing creatine to an animal, comprising:
receiving an ester derivative of creatine by the animal, wherein the ester derivative of creatine is suitable for acting as a pronutrient in an animal.
- 26. The method as described in claim 25, wherein the ester derivative of creatine acts as a pronutrient in the gastrointestinal tract of the animal.
- 27. The method as described in claim 25, wherein the pronutrient is metabolized by the animal to form creatine.
- 28. The method as described in claim 27, wherein the pronutrient is metabolized by an esterase.
- 29. The method as described in claim 28, wherein the pronutrient is metabolized by esterases in at least one of an intestinal lumen, epithelial cell and blood.
- 30. The method as described in claim 25, wherein the pronutrient is metabolized by the animal for form an alcohol.
- 31. The method as described in claim 25, wherein the creatine ester is suitable for being formed in a solid form capable of being ingested by the animal.
- 32. The method as described in claim 31, wherein the solid form includes the creatine ester and at least one of dextrose and phosphate.
- 33. The method as described in claim 31, wherein the solid form is configured as at least one of a tablet and a capsule.
- 34. The method as described in claim 25, wherein the creatine ester is suitable for liquid delivery.
- 35. The method as described in claim 34, wherein the creatine ester includes at least one of an aqueous solution and emulsion.
- 36. The method as described in claim 25, wherein the creatine ester includes at least one of creatine ethyl ester, creatine benzyl ester, creatine phosphoester, monocreatine glycerol, t-butyl creatine ester, dicreatine glycerol and tricreatine glycerol.
- 37. The method as described in claim 25, wherein the creatine ester is received by the animal, the creatine ester is modified by the animal into creatine and an alcohol.
- 38. The method as described in claim 37, wherein the creatine ester is modified by the animal into creatine and alcohol by an esterase.
- 39. The method as described in claim 37, wherein the creatine ester is modified by at least one of an intestinal lumen, epithelial cell and blood of the animal into creatine.
- 40. The method as described in claim 25, further comprising forming a creatine ester, wherein an acid moiety of creatine is modified to provide an ester bond.
- 41. The method as described in claim 25, wherein the animal includes human and livestock.
- 42. A composition of matter, comprising:
- 43. The composition of matter as described in claim 42, wherein R represents an ester so as to form a composition of matter including at least one of creatine benzyl ester, creatine phosphoester, monocreatine glycerol, t-butyl creatine ester, dicreatine glycerol and tricreatine glycerol.
- 44. The composition of matter as described in claim 42, wherein the composition of matter is suitable for being converted to creatine upon receipt by an animal.
- 45. The composition of matter as described in claim 44, wherein upon receipt of the composition of matter by the animal, creatine and an alcohol are formed.
- 46. The composition of matter as described in claim 42, wherein a salt is formed of the composition of matter.
- 47. A method of producing a creatine pronutrient, comprising:
reacting at least one of an anhydrous creatine and hydrated form of creatine with an alcohol in an acidic environment, wherein a product is formed including a creatine ester pronutrient.
- 48. The method as described in claim 47, wherein the hydrated form of creatine includes creatine monohydrate.
- 49. The method as described in claim 47, wherein the alcohol includes at least one of ethyl alcohol and benzyl alcohol.
- 50. The method as described in claim 47, wherein the acidic environment is achieved through hydrochloric acid being present.
- 51. The method as described in claim 47, further comprising purifying the product.
- 52. The method as described in claim 51, wherein the product is purified by solvating the product in an alcohol and then cooling to form purified creatine ester.
CROSS REFERENCE TO RELATED APPLICATIONS
[0001] The present application claims priority under 35 U.S.C. §119(e) to U.S. Provisional Application No. 60/232,969 filed Sep. 14, 2000, which is herein incorporated by reference in its entirety.
PCT Information
Filing Document |
Filing Date |
Country |
Kind |
PCT/US01/28788 |
9/14/2001 |
WO |
|