CRIF:MU-Purchase of a Liquid Chromatograph Time-of-Flight Mass Spectrometer

Information

• NSF Award
• 0741868

Owner

• CORPORATION OF GONZAGA UNIVERSITY, THE

• Award Id

  0741868

• Award Effective Date

  2/1/2008 - 17 years ago

• Award Expiration Date

  1/31/2011 - 14 years ago

• Award Amount

  $ 286,753.00

• Award Instrument

  Standard Grant

With support from the Chemistry Research Instrumentation and Facilities - Multiuser Instrumentation (CRIF-MU) Program, the Department of Chemistry at Gonzaga University will purchase a liquid chromatography time-of-flight mass spectrometer. Examples of undergraduate research projects that will be performed which utilize LC-TOFMS include: 1) Characterization of synthetic substrates and natural products used in quinine biosynthesis; 2) Analysis of metabolites in lipid extracts from anaerobic respiration; 3) Structure-function studies of enzymes that involve determination of protein mass and quantification of known proteins; 4) Synthetic design and characterization of a positron emission tomography (PET) diagnostic agent; 5) Development of wound care dressings for chronic wounds; and 6) Mechanism and conformational dynamics of enzymes by hydrogen-deuterium exchange measurements.<br/><br/>Liquid chromatography with mass spectrometric detection (LC/MS) is an extremely powerful technique used for the separation and analysis of complex mixtures. This instrument will substantially strengthen scientific research at this primarily undergraduate institution, and these studies will have a solid impact in the areas of medicinal chemistry and biochemistry.

• Program Officer

  Carlos A. Murillo

• Min Amd Letter Date

  1/9/2008 - 17 years ago

• Max Amd Letter Date

  1/9/2008 - 17 years ago

• ARRA Amount

• Name

  Gonzaga University

• City

  Spokane

• State

  WA

• Country

  United States

• Address

  502 East Boone Avenue

• Postal Code

  992580087

• Phone Number

  5093136102

• First Name

  Joanne

• Last Name

  Smieja

• Email Address

  smieja@gonzaga.edu

• Start Date

  1/9/2008 12:00:00 AM

• First Name

  Jennifer

• Last Name

  Shepherd

• Email Address

  shepherd@gonzaga.edu

• Start Date

  1/9/2008 12:00:00 AM

• First Name

  Jeff

• Last Name

  Cronk

• Email Address

  cronk@gonzaga.edu

• Start Date

  1/9/2008 12:00:00 AM

• First Name

  Stephen

• Last Name

  Warren

• Email Address

  warren@gonzaga.edu

• Start Date

  1/9/2008 12:00:00 AM

• First Name

  Jeffrey

• Last Name

  Watson

• Email Address

  watsonj@gonzaga.edu

• Start Date

  1/9/2008 12:00:00 AM