Claims
- 1. A composition for application to and protection of phosphoglyceride-containing biological and synthetic membranes from the disruptive effects of freezing, thawing, and freeze-drying, comprising a dispersion of molecules, each molecule consisting of a cholesterol moiety modified at the 3-position by the attachment of a carbohydrate moiety located at a predetermined, variable distance from said cholesterol moiety by means of a hydrophilic polyoxyethylene unit of predetermined variable length.
- 2. A composition as in claim 1, wherein said polyoxyethylene unit ranges from six to twelve angstroms in length.
- 3. A composition as in claim 1, wherein said carbohydrate moiety is maltose.
Government Interests
This invention was made with support from the U.S. Government through the U.S. Army Research Office under Grant number DAAG-29-83-K-0128 and also with support from the National Institute of General Medical Sciences under National Service Award T32GM07616. The U.S. Government has certain rights in the invention.
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