Claims
- 1. Crystalline 2S-cis-3-[[(4-mercapto-2-pyrrolidinyl)carbonyl]amino]benzoic acid or a pharmaceutically acceptable salt or solvate thereof.
- 2. Crystalline 2S-cis-3-[[(4-mercapto-2-pyrrolidinyl)carbonyl]amino]benzoic acid in accordance with claim 1, having an X-ray powder diffraction pattern in accordance with FIG. 1, 2 or 3.
- 3. Crystalline 2S-cis-3-[[(4-mercapto-2-pyrrolidinyl)carbonyl]amino]benzoic acid in accordance with claim 1 as the hydrochloride salt.
- 4. Crystalline 2S-cis-3-[[(4-mercapto-2-pyrrolidinyl)carbonyl]amino]benzoic acid in accordance with claim 3 as the hydrochloride salt unsolvated form.
- 5. Crystalline 2S-cis-3-[[(4-mercapto-2-pyrrolidinyl)carbonyl]amino]benzoic acid in accordance with claim 3 as the hydrochloride salt 1-butanol solvate.
- 6. Crystalline 2S-cis-3-[[(4-mercapto-2-pyrrolidinyl)carbonyl]amino]benzoic acid in accordance with claim 3 as the hydrochloride salt acetic acid solvate.
- 7. Crystalline 2S-cis-3-[[(4-mercapto-2-pyrrolidinyl)carbonyl]amino]benzoic acid in accordance with claim 1, having one of the following X-ray powder diffraction patterns:
- TABLE______________________________________d - Spacings (.ANG.) - HCl salt Unsolvated 1-butanol solvate Acetic acid solvate______________________________________5.5 14.6 5.4 5.3 7.3 5.3 4.9 5.6 5.1 4.3 4.9 4.2 4.1 4.2 3.8 3.9 4.0 3.6 3.8 3.9 3.4 3.7 3.8 3.1 3.6 3.7 2.7 3.3 3.6 2.6 3.2 3.5 2.9 3.3 2.6 3.0 2.3 2.9______________________________________
RELATED APPLICATION
This application claims the benefit of Ser. No. 60/052,197 filed on Jul. 10, 1997.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
5478820 |
Betts et al. |
Dec 1995 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
WO 9706154 |
Feb 1997 |
WOX |