The subject matter disclosed herein relates to non-invasive imaging and, in particular, to spectral calibration of a radiographic imaging system.
In the fields of medical imaging and security screening, non-invasive imaging techniques have gained importance due to benefits that include unobtrusiveness, convenience, and speed. In medical and research contexts, non-invasive imaging techniques are used to image organs or tissues beneath the surface of the skin. Similarly, in industrial or quality control (QC) contexts, non-invasive imaging techniques are used to examine parts or items for hidden defects that may not be evident from an external examination. In security screening, non-invasive imaging techniques are typically used to examine the contents of containers (e.g., packages, bags, or luggage) without opening the containers and/or to screen individuals entering or leaving a secure location.
One example of a non-invasive imaging system is a computed tomography (CT) imaging system in which an X-ray source emits radiation (e.g., X-rays) towards an object or subject (e.g., a patient, a manufactured part, a package, or a piece of baggage) from a variety of different angular positions. The emitted X-rays, after being attenuated by the subject or object, typically impinge upon an array of radiation detector elements of an electronic detector, which generates signals indicate of the incident radiation at different locations on the detector. The intensity of radiation reaching the detector is typically dependent on the attenuation and absorption of X-rays through the scanned subject or object. The signals generated at the detector are processed to generate images and/or volumetric representations of the internal structures of the subject or object.
Such a CT system may be subject to various artifacts, such as beam hardening artifacts, ring/band artifacts, and/or scatter-induced artifacts. To mitigate such artifacts, a spectral calibration process may be performed using a variety of calibration phantoms. However, as the scan coverage of such CT systems has increased (particularly in the dimension extending through the imaging bore, i.e., the Z-direction), the phantoms have grown correspondingly larger to accommodate the increased scan coverage. The increased size of such calibration phantoms can make performing spectral calibrations by attaching the phantom at the edge of the patient table increasingly difficult.
In one embodiment, a method for calibrating a CT system is provided. In accordance with this method, an air scan is acquired at a specified peak voltage (kVp). A phantom scan is also acquired at the kVp. The phantom scan is acquired by scanning the respective phantom on a table. Projections associated with the air scan and the phantom scan are processed with a preliminary beam hardening correction function. An image is reconstructed using the corresponding corrected projections. The image is segmented to remove non-phantom components. The segmented image is processed to generate an image pair comprising a phantom image with artifacts and a phantom image without artifacts. The image pair is projected to generate a projection pair. A respective deviation ratio is derived for the projection pair. The acquiring, processing projections, reconstructing segmenting, processing the segmented image, projecting, and deriving steps are repeated for a specified range of kVp, filters, and phantoms. A number of phantoms can be used to cover the attenuation range utilized by the CT system. Spectral calibration vectors are derived based on the respective deviation ratios.
In another embodiment, a method for acquiring phantom scan data is provided. In accordance with this embodiment, a phantom is positioned on a table and within a bore of a CT imaging system. The CT imaging system is operated to acquire projection data while the phantom is on the table and within the bore.
In a further embodiment, a method for calibrating a CT imaging system is provided. In accordance with this embodiment, a plurality of air scans are acquired at different kVp and with different filters. A plurality of phantom scans are acquired at the different kVp, with the different filters, and using different phantoms. The plurality of phantom scans are acquired with the respective phantoms positioned on a table within the field of view of the CT imaging system. The respective plurality of air scans and the respective plurality of phantom scans are processed to derive one or more spectral calibration vectors for the CT imaging system.
These and other features, aspects, and advantages of the present invention will become better understood when the following detailed description is read with reference to the accompanying drawings in which like characters represent like parts throughout the drawings, wherein:
The present disclosure provides for using large scan phantoms for performing spectral calibration of a CT imaging system. In accordance with the present approach, a phantom may be positioned on the support table during the calibration process. Contributions from the table to the acquired calibration data are removed from the calibration measurements as part of calibration process. In this manner, the CT system may undergo spectral calibration even though the calibration scan data initially includes data corresponding to other structures in addition to the calibration phantom.
With the foregoing in mind and in accordance with one embodiment, a CT imaging system is provided. The present discussion is generally provided in the context of a 3rd generation CT system, however, the present disclosure is equally applicable to other systems. For simplicity, the present discussion generally describes the use of detectors and X-ray imaging systems in a medical imaging context. However, it should be appreciated that the described radiation detectors may also be used in non-medical contexts (such as security and screening systems and non-destructive testing and/or detection systems).
Referring to
Rotation of gantry 12 and the operation of X-ray source 14 are governed by a control mechanism 26 of CT system 10. Control mechanism 26 includes an X-ray controller 28 that provides power and timing signals to an X-ray source 14 and a gantry motor controller 30 that controls the rotational speed and position of gantry 12. An image reconstructor 34 receives sampled and digitized X-ray data from DAS 32 and performs high-speed reconstruction. The reconstructed image is applied as an input to a computer 36, which stores the image in a mass storage device 38. Computer 36 also receives commands and scanning parameters from an operator via console 40. An associated display 42 allows the operator to observe the reconstructed image and other data from computer 36. The operator supplied commands and parameters are used by computer 36 to provide control signals and information to DAS 32, X-ray controller 28, and gantry motor controller 30. In addition, computer 36 operates a table motor controller 44, which controls a motorized table 46 to position a patient or object undergoing imaging (e.g., the spectral calibration phantom 22, within the gantry 12. Particularly, table 46 moves portions of the subject or other object through a gantry opening 48.
In conventional approaches, a CT imaging system 10 may undergo a spectral calibration process to allow for the correction or removal of soft tissue beam hardening artifacts, as well as ring/band artifacts arising from detector imperfections. In addition, the spectral calibration may allow scatter induced artifacts to be suppressed or removed. During a conventional spectral calibration process, cylindrical water phantoms (such as the generalized water phantom 22 of
However, as cone-beam CT systems have developed with increased coverage in the Z-direction, i.e., along the axis running through the imaging bore, the size of the cylindrical calibration phantoms has also increased to accommodate the extent of the increased Z-coverage. For example, a CT scanner with 40 mm coverage in the Z-direction may utilize a calibration phantom that is 80 mm long and more than 40 cm in diameter. Likewise, as Z-coverage extends to 80 mm, 320 mm and so forth, the size of the respective calibration phantoms increases correspondingly. As a result, the calibration phantoms have become so heavy that it is difficult for the phantoms to be held or suspended from the edge of the table.
As discussed herein, approaches are disclosed for scanning the calibration phantom 22 while positioned on the table 46 (as depicted in
With the foregoing in mind, and turning now to
After data collection, deviations from the expected values are determined. As will be appreciated, when the table 46 is present in the X-ray beam, the measured projections can be of un-controlled shape. It is presumed that one does not have a direct expectation of these projections that represent the ideal case and free of artifacts attributable to detector imperfections and beam hardening. However, in a successfully calibrated system, the phantom should be uniform at the targeted Hounsfield units (HU) value.
In the measurement, the table 46 should contribute little to the attenuation compared to the phantom 22. Therefore, it would be a reasonable approximation that the deviations from the ideal condition in the image reconstructed with preliminary beam hardening correction vectors, which can be computed theoretically, would be contributed mostly by the phantom 22. With this assumption, a new pair of physical and ideal projections can be obtained by processing (block 70) the measured projections pDd in accordance with:
Where, ƒD( ) is the preliminary beam hardening correction functional form, mostly in the polynomial format.
In one implementation, the preliminary beam hardening corrected projections 72 are reconstructed (block 74) to form an image 76 (i.e., Ig(x, y)). The image 76 may not be fully corrected and may include rings/bands and/or HU differences (i.e., non-uniformities) in the phantom (e.g., water) region. The phantom cylinder in image Ig(x, y) is segmented (block 78), eliminating the table 46 and any other non-phantom components from the image 76. The segmented image 80 may be processed (block 82) to represent the ideal image by setting the phantom (e.g., water) HU value to the targeted value, e.g., 1000, yielding pairs of phantom (e.g., water cylinder) images, one image 84 (i.e., Ig(x′, y′)) with artifacts, and one image 86 (i.e., Igideal(x′, y′)) without artifacts. Such processing may be threshold-based, taking advantage of the relatively weak attenuation provided by the table in comparison to the water in the phantom.
The paired images 84, 86 (i.e., Ig(x′, y′) and Igideal(x′, y′)) are forward projected (block 88) to the same ray path as the corresponding measured projections pDd, resulting in paired projection sets 90, 92 (i.e., pƒDd, pƒD,ideald). The deviation of the projection from the ideal value for each phantom is described (block 94) by the deviation ratio 96:
at a total projection (uncorrected) value of pDd. With a reasonably good preliminary calibration vector set, the computed deviation ratio 96 (i.e., rDd) describes the characteristic of the CT detection system, with a value typically close to 1.0. This procedure is repeated for all the phantom sizes, indexed by d. In one implementation, three to four phantoms are used to fully cover the calibration range.
For a given detector index, D, the spectral calibration vectors 100 can be obtained (block 98) by combining the preliminary beam hardening correction functions and the deviation ratio 96 (i.e., rDd) from all phantoms 22, i.e., by updating the beam hardening correction functions with the extracted deviations from the ideal. For example, in one embodiment, correction data pairs are generated using the preliminary beam hardening correction for projection values covering a range of interest, such as:
(p,ƒD(p)) (3)
where p ranges from 0 to 12.0, with a step of 0.2. In addition, data points are generated using the phantom measurements such that each phantom measurement (e.g., 3 or 4 phantom measurements) yield a set of data pairs that can be used to generate an ideal phantom image (e.g., water image) free of artifacts. For example, in one embodiment these data sets are generated as:
pDd,ƒD(pDd)·rDd (4)
where rDd provided the desired correction.
The data pair points generated using the preliminary beam hardening correction and those generated from the phantom measurement are combined to include both the correction provided by preliminary calibration vectors and additional correction from measurements. The data pairs from the preliminary calibration are included to confine the fitting to follow the trend of the functional curve. The new data pair sets can be expressed as:
{pDd;p→ƒD(p);ƒD(pDd)·rDd}. (5)
In one implementation, the above data pairs are fitted with the designated functional form for the spectral calibration. In one embodiment, more weight is given to the data pairs deduced from measurements (that is the data pairs deduced in accordance with equation (4). In the polynomial format, the data sets are fitted with a polynomial form, such as a 3rd to 4th order form, resulting in typically calibration vectors 100 (e.g., a1, a2, a3, aN), satisfying:
(ƒD(p);ƒD(pDd)·rDd)=a1·(p;pDd)+a2·(p;pDd)2+a3·(p;pDd)3 (6)
The new calibration vectors are used as the preliminary beam hardening correction, as depicted at block 70, and the process is iterated a set number of times, until a cost or other threshold function is satisfied, or until a satisfactory calibration vectors (as determined by any suitable criteria) are obtained for all the detector cells in the system. Thus, as discussed above, the algorithm discussed herein provides a way to perform spectral calibration for a CT system with phantoms placed directly on the patient table, without requiring precise phantom centering.
Technical effects of the invention include spectral calibration of a CT system using a phantom that is scanned while on the patient table. Other technical effects include removing non-phantom contributions from calibration scan data to facilitate calibration of an imaging system. Additional technical effects include deriving a deviation ratio describing the deviation of a set of measured calibration projections from corresponding set of ideal calibration projections and calculating calibration vectors using the deviation ratio.
This written description uses examples to disclose the invention, including the best mode, and also to enable any person skilled in the art to practice the invention, including making and using any devices or systems and performing any incorporated methods. The patentable scope of the invention is defined by the claims, and may include other examples that occur to those skilled in the art. Such other examples are intended to be within the scope of the claims if they have structural elements that do not differ from the literal language of the claims, or if they include equivalent structural elements with insubstantial differences from the literal languages of the claims.
This application is a Non-Provisional of U.S. Provisional Patent Application No. 61/289,828, entitled “CT Spectral Calibration”, filed Dec. 23, 2009, which is herein incorporated by reference in its entirety for all purposes.
Number | Name | Date | Kind |
---|---|---|---|
5359638 | Hsieh et al. | Oct 1994 | A |
5668846 | Fox et al. | Sep 1997 | A |
5907593 | Hsieh et al. | May 1999 | A |
6023494 | Senzig et al. | Feb 2000 | A |
6115487 | Toth et al. | Sep 2000 | A |
6198791 | He et al. | Mar 2001 | B1 |
6275560 | Blake et al. | Aug 2001 | B1 |
6285741 | Ackelsberg et al. | Sep 2001 | B1 |
6304625 | Senzig et al. | Oct 2001 | B1 |
6385277 | Li et al. | May 2002 | B1 |
6389096 | Hoffman et al. | May 2002 | B1 |
6393090 | Hsieh et al. | May 2002 | B1 |
6421412 | Hsieh et al. | Jul 2002 | B1 |
6650928 | Gailly et al. | Nov 2003 | B1 |
6661866 | Limkeman et al. | Dec 2003 | B1 |
6801594 | Hsieh et al. | Oct 2004 | B1 |
6810102 | Hsieh et al. | Oct 2004 | B2 |
6816567 | Drummond | Nov 2004 | B2 |
6836528 | Reddy et al. | Dec 2004 | B2 |
6848827 | Wu et al. | Feb 2005 | B2 |
6904118 | Wu et al. | Jun 2005 | B2 |
6904120 | Wu et al. | Jun 2005 | B2 |
6904127 | Toth et al. | Jun 2005 | B2 |
6947584 | Avila et al. | Sep 2005 | B1 |
7006592 | Ali et al. | Feb 2006 | B2 |
7016457 | Senzig et al. | Mar 2006 | B1 |
7031425 | Hsieh et al. | Apr 2006 | B2 |
7031426 | Iatron et al. | Apr 2006 | B2 |
7086780 | Wu et al. | Aug 2006 | B2 |
7139000 | Doan et al. | Nov 2006 | B2 |
7177453 | Suryanarayanan et al. | Feb 2007 | B2 |
7211046 | Deller et al. | May 2007 | B2 |
7260172 | Arenson et al. | Aug 2007 | B2 |
7260174 | Hoffman et al. | Aug 2007 | B2 |
7280631 | De Man et al. | Oct 2007 | B2 |
7283605 | Sainath et al. | Oct 2007 | B2 |
7298812 | Tkaczyk et al. | Nov 2007 | B2 |
7308073 | Tkaczyk et al. | Dec 2007 | B2 |
7346203 | Turek et al. | Mar 2008 | B2 |
7379527 | Wu et al. | May 2008 | B2 |
7382853 | Arenson et al. | Jun 2008 | B2 |
7391844 | Wu et al. | Jun 2008 | B2 |
7433443 | Tkaczyk et al. | Oct 2008 | B1 |
7466793 | Wu | Dec 2008 | B2 |
7492855 | Hopkins et al. | Feb 2009 | B2 |
7532702 | Hsieh et al. | May 2009 | B2 |
7570736 | Hoffman et al. | Aug 2009 | B2 |
7583790 | Hoffman et al. | Sep 2009 | B2 |
7593502 | Katcha et al. | Sep 2009 | B2 |
7606347 | Tkaczyk et al. | Oct 2009 | B2 |
7609802 | Langan et al. | Oct 2009 | B2 |
7613274 | Tkaczyk et al. | Nov 2009 | B2 |
7634060 | Hoffman et al. | Dec 2009 | B2 |
7697657 | Walter et al. | Apr 2010 | B2 |
7697659 | Hoffman et al. | Apr 2010 | B2 |
7724865 | Wu et al. | May 2010 | B2 |
7747057 | Wu et al. | Jun 2010 | B2 |
7756239 | Wu et al. | Jul 2010 | B2 |
7792241 | Wu et al. | Sep 2010 | B2 |
7801264 | Wu et al. | Sep 2010 | B2 |
7813474 | Wu et al. | Oct 2010 | B2 |
7826587 | Langan et al. | Nov 2010 | B1 |
7835486 | Basu et al. | Nov 2010 | B2 |
7869571 | Hsieh et al. | Jan 2011 | B2 |
7885372 | Edic | Feb 2011 | B2 |
20040066911 | Hsieh et al. | Apr 2004 | A1 |
20060109950 | Arenson et al. | May 2006 | A1 |
20060173270 | Weiner et al. | Aug 2006 | A1 |
20060264749 | Weiner et al. | Nov 2006 | A1 |
20070124169 | Irving et al. | May 2007 | A1 |
20070147579 | De Man et al. | Jun 2007 | A1 |
20070147580 | Wu et al. | Jun 2007 | A1 |
20080056432 | Pack et al. | Mar 2008 | A1 |
20080159611 | Tao et al. | Jul 2008 | A1 |
20090003511 | Roy et al. | Jan 2009 | A1 |
20090052621 | Walter et al. | Feb 2009 | A1 |
20090161939 | Wu et al. | Jun 2009 | A1 |
20090214095 | Wu et al. | Aug 2009 | A1 |
20090304249 | Wu | Dec 2009 | A1 |
20100020921 | Dong et al. | Jan 2010 | A1 |
20100128948 | Thomsen et al. | May 2010 | A1 |
20110026668 | Wu et al. | Feb 2011 | A1 |
20110052022 | Xu et al. | Mar 2011 | A1 |
Number | Date | Country | |
---|---|---|---|
20110249879 A1 | Oct 2011 | US |
Number | Date | Country | |
---|---|---|---|
61289828 | Dec 2009 | US |