CYCLOSPORINE IMPLANT FOR CORNEAL GRAFT REJECTION

Information

• Research Project
• 6384772

• ApplicationId

  6384772

• Core Project Number

  R44EY012338

• Full Project Number

  5R44EY012338-03

• Serial Number

  12338

• FOA Number

• Sub Project Id

• Project Start Date

  9/30/1998 - 25 years ago

• Project End Date

  9/29/2002 - 21 years ago

• Program Officer Name

  FISHER, RICHARD S

• Budget Start Date

  9/30/2001 - 22 years ago

• Budget End Date

  9/29/2002 - 21 years ago

• Fiscal Year

  2001

• Support Year

  3

• Suffix

• Award Notice Date

  9/28/2001 - 22 years ago

Organizations

• Control Delivery Systems, Inc.

DESCRIPTION: The goal of this fast-track phase I / II proposal is to reduce or eliminate blindness due to rejection of corneal transplants in high risk, penetrating keratoplasty. The specific aim of the phase I project is to test the efficacy of a cyclosporine implant in a rabbit model of corneal graft rejection. If the implant is ineffective in the rabbit model phase II funds will not be sought. Phase II of this proposal will assess the safety and efficacy of the implant in patients at high risk of graft failure. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

IC Name

• Activity

  R44

• Administering IC

  EY

• Application Type

  5

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

  296944

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  867

• Ed Inst. Type

• Funding ICs

  NEI:296944\

• Funding Mechanism

• Study Section

  ZRG1

• Study Section Name

  Special Emphasis Panel

• Organization Name

  CONTROL DELIVERY SYSTEMS, INC.

• Organization Department

• Organization DUNS

• Organization City

  WATERTOWN

• Organization State

  MA

• Organization Country

  UNITED STATES

• Organization Zip Code

  02172

• Organization District

  UNITED STATES