Claims
- 1. A system for administering an active substance to a patient comprising:a source of a contrast or enhancement medium; at least a first delivery unit in fluid connection with the source of contrast or enhancement medium; at least a second delivery unit in fluid communication with an active substance; an imaging energy source adapted to apply imaging energy to a region of the patient; an imaging unit providing an indication of an internal view of the patient based upon a signal resulting from the imaging energy applied to the region of the patient, the signal being affected by a condition of the contrast or enhancement medium in the patient; and a control unit adapted to control the administration of the active substance based on the indication.
- 2. The system of claim 1 wherein the active substance comprises at least one of a therapeutic drug and a gene therapy.
- 3. The system of claim 1 wherein the active substance comprises a diagnostic substance.
- 4. The system of claim 1 wherein the energy applied to the region of the patient is sonic energy and the signal is an acoustical signal.
- 5. The system of claim 1 wherein the energy source is further operable to activate the active substance.
- 6. The system of claim 1 wherein the control unit is further adapted to control the at least a second delivery unit.
- 7. The system of claim 1 wherein the control is further adapted to control the at least the first and the at least the second delivery unit.
- 8. The system of claim 1, further comprising:an activating energy source adapted to activate the active substance.
- 9. The system of claim 8 wherein the imaging energy source and the activation energy source provide the same type of energy.
- 10. The system of claim 8 wherein the imaging energy source and the activation energy source is sonic energy.
- 11. The system of claim 1, further comprising:a source of the active substance.
- 12. The system of claim 1 wherein the source of contrast or enhancement medium further comprises the active substance.
- 13. A system for administering an active substance to a patient comprising:a source of a contrast or enhancement medium; at least one delivery unit in fluid communication with both the source of contrast or enhancement medium and an active substance; an imaging energy source adapted to apply imaging energy to a region of the patient; an imaging unit providing an indication of an internal view of the patient based upon a signal resulting from the imaging energy applied to the region of the patient, the signal being affected by a condition of the contrast or enhancement medium in the patient; and a control unit adapted to control the administration of the active substance based on the indication.
- 14. The system of claim 13 wherein the active substance comprises at least one of a therapeutic drug and a gene therapy.
- 15. The system of claim 13 wherein the active substance comprises a diagnostic substance.
- 16. The system of claim 13 wherein the energy applied to the region of the patient is sonic energy and the signal is an acoustical signal.
- 17. The system of claim 13 wherein the energy source is further operable to activate the active substance.
- 18. The system of claim 13 wherein the control unit is further adapted to control the at least one delivery unit.
- 19. The system of claim 13, further comprising:an activating energy source adapted to activate the active substance.
- 20. The system of claim 19 wherein the imaging energy source and the activation energy source provide the same type of energy.
- 21. The system of claim 19 wherein the imaging energy source and the activation energy source is sonic energy.
- 22. The system of claim 13, further comprising:a source of the active substance.
- 23. The system of claim 13 wherein the source of contrast or enhancement medium further comprises the active substance.
- 24. A system for administering an active substance to a patient comprising:a source of a contrast or enhancement medium; at least one delivery unit in fluid communication with one or both of the source of contrast or enhancement medium and an active substance for delivering the contrast or enhancement medium or the active substance to the patient, wherein the active substance comprises at least one of a therapeutic drug and a gene therapy; an imaging energy source adapted to apply imaging energy to a region of the patient; an imaging unit providing an indication of an internal view of the patient based upon a signal resulting from the imaging energy applied to the region of the patient, the signal being affected by a condition of the contrast or enhancement medium in the patient; and a control unit adapted to control the administration of the active substance based on the indication.
- 25. The system of claim 24 wherein the energy applied to the region of the patient is sonic energy and the signal is an acoustical signal.
- 26. The system of claim 24 wherein the energy source is further operable to activate the active substance.
- 27. The system of claim 24 wherein the control unit is further adapted to control the at least one delivery unit.
- 28. The system of claim 24, further comprising:an activating energy source adapted to activate the active substance.
- 29. The system of claim 28 wherein the imaging energy source and the activation energy source provide the same type of energy.
- 30. The system of claim 28 wherein the imaging energy source and the activation energy source is sonic energy.
- 31. The system of claim 24, further comprising:a source of the active substance.
- 32. The system of claim 24 wherein the source of contrast or enhancement medium further comprises the active substance.
- 33. The system of claim 24 wherein the at least one delivery unit comprises at least two deliver units, a first delivery unit in fluid communication with the source of contrast or enhancement medium and a second delivery unit in fluid communication with the active substance.
- 34. A method for administering an active substance to a patient comprising:providing a source of a contrast or enhancement medium; providing at least one delivery unit in fluid connection with one or both of the source of contrast or enhancement medium and an active substance for delivering the contrast or enhancement medium or the active substance to the patient, wherein the active substance comprises at least one of a therapeutic drug and a gene therapy; injecting the contrast or enhancement medium into the patient; providing an imaging energy source adapted to apply imaging energy to a region of the patient; applying energy to the region of the patient; providing an imaging unit providing an indication of an internal view of the patient based upon a signal resulting from the imaging energy applied to the region of the patient, the signal being affected by a condition of the contrast or enhancement medium in the patient; generating an indication of an internal view of the patient; and controlling the administration of the active substance based on the indication.
- 35. The method of claim 34 wherein the energy applied to the region of the patient is sonic energy and the signal is an acoustical signal.
- 36. The method of claim 34 wherein the energy source is further operable to activate the active substance.
- 37. The method of claim 34 wherein the control unit is further adapted to control the at least one delivery unit.
- 38. The method of claim 34, further comprising:providing an activating energy source adapted to activate the active substance.
- 39. The method of claim 38 wherein the imaging energy source and the activation energy source provide the same type of energy.
- 40. The method of claim 38 wherein the imaging energy source and the activation energy source is sonic energy.
- 41. The system of claim 34, further comprising:a source of the active substance.
- 42. The system of claim 34 wherein the source of contrast or enhancement medium further comprises the active substance.
- 43. A system for administering an active substance to a patient comprising:a source of an ultrasound contrast or enhancement medium containing the active substance; at least one delivery unit in fluid communication with the source of contrast or enhancement medium and an active substance for delivering the contrast or enhancement medium or the active substance to the patient; an imaging energy source adapted to apply imaging energy to a region of the patient; an imaging unit providing an indication of an internal view of the patient based upon a signal resulting from the imaging energy applied to the region of the patient, the signal being affected by a condition of the contrast or enhancement medium in the patient; and a control unit adapted to control the administration of the active substance based on the indication.
- 44. The system of claim 43 wherein the energy applied to the region of the patient is sonic energy and the signal is an acoustical signal.
- 45. The system of claim 43 wherein the energy source is further operable to activate the active substance.
- 46. The system of claim 43 wherein the control unit is further adapted to control the at least one delivery unit.
- 47. The system of claim 43, further comprising:an activating energy source adapted to activate the active substance.
- 48. The system of claim 43 wherein the imaging energy source and the activation energy source provide the same type of energy.
- 49. The system of claim 47 wherein the imaging energy source and the activation energy source is sonic energy.
- 50. A system for administering an active substance to a patient comprising:a source of a contrast or enhancement medium; at least one delivery unit in fluid communication with one or both of the source of contrast or enhancement medium and the active substance for delivering the contrast or enhancement medium or an active substance to the patient, wherein the active substance comprises at least one of a therapeutic drug and a gene therapy; an imaging energy source adapted to apply imaging energy to a region of the patient and to activate the active substance; an imaging unit providing an indication of an internal view of the patient based upon a signal resulting from the imaging energy applied to the region of the patient, the signal being affected by a condition of the contrast or enhancement medium in the patient; and a control unit adapted to control the administration of the active substance based on the indication.
- 51. A system for administering an active substance to a patient comprising:a source of a contrast or enhancement medium; at least one delivery unit in fluid communication with one or both of the source of contrast or enhancement medium and the active substance for delivering the contrast or enhancement medium or an active substance to the patient, wherein the active substance comprises at least one of a therapeutic drug and a gene therapy; an imaging energy source adapted to apply imaging energy to a region of the patient; an imaging unit providing an indication of an internal view of the patient based upon a signal resulting from the imaging energy applied to the region of the patient, the signal being affected by a condition of the contrast or enhancement medium in the patient; and a control unit adapted to control the at least one delivery unit and the administration of the active substance based on the indication.
- 52. A system for administering an active substance to a patient comprising:a source of a contrast or enhancement medium; at least one delivery unit in fluid communication with one or both of the source of contrast or enhancement medium and the active substance for delivering the contrast or enhancement medium or an active substance to the patient, wherein the active substance comprises at least one of a therapeutic drug and a gene therapy; an imaging energy source adapted to apply imaging energy to a region of the patient; an activating energy source adapted to activate the active substance; an imaging unit providing an indication of an internal view of the patient based upon a signal resulting from the imaging energy applied to the region of the patient, the signal being affected by a condition of the contrast or enhancement medium in the patient; and a control unit adapted to control the administration of the active substance based on the indication.
- 53. A system for administering an active substance to a patient comprising:a source of a contrast or enhancement medium; at least one delivery unit in fluid communication with one or both of the source of contrast or enhancement medium and an active substance for delivering the contrast or enhancement medium or the active substance to the patient, wherein the active substance comprises at least one of a therapeutic drug and a gene therapy; a sonic imaging energy source adapted to apply imaging energy to a region of the patient; a sonic activating energy source adapted to activate the active substance; an imaging unit providing an indication of an internal view of the patient based upon a signal resulting from the imaging energy applied to the region of the patient, the signal being affected by a condition of the contrast or enhancement medium in the patient; and a control unit adapted to control the administration of the active substance based on the indication.
RELATED REFERENCES
The present application is a continuation-in-part of U.S. patent application Ser. No. 09/197,773, filed on Nov. 23, 1998, which is a divisional of U.S. patent application Ser. No. 08/309,820, filed on Sep. 21, 1994, now U.S. Pat. No. 5,840,026, the disclosures of which are incorporated herein by reference.
US Referenced Citations (11)
Foreign Referenced Citations (4)
Number |
Date |
Country |
32 03 594 |
Aug 1983 |
DE |
197 02 896 |
Jul 1997 |
DE |
196 47 701 |
May 1998 |
DE |
2 328 745 |
Mar 1999 |
GB |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
09/197773 |
Nov 1998 |
US |
Child |
09/300326 |
|
US |