Defining T cell epitopes in Dengue virus infection

Information

• Research Project
• 7270889

• ApplicationId

  7270889

• Core Project Number

  R43AI062177

• Full Project Number

  1R43AI062177-01A2

• Serial Number

  62177

• FOA Number

  PA-06-34

• Sub Project Id

• Project Start Date

  6/1/2007 - 17 years ago

• Project End Date

  5/31/2009 - 15 years ago

• Program Officer Name

  CASSETTI, CRISTINA

• Budget Start Date

  6/1/2007 - 17 years ago

• Budget End Date

  5/31/2008 - 16 years ago

• Fiscal Year

  2007

• Support Year

  1

• Suffix

  A2

• Award Notice Date

  5/29/2007 - 17 years ago

Organizations

• Immunotope, Inc.

[unreadable] DESCRIPTION (provided by applicant): Dengue Fever (DF) and Dengue Hemorrhagic Fever (DHF) are significant global public health problems and understanding the overall immune response to infection will contribute to appropriate management of the disease and its potentially severe complications. Live attenuated and subunit vaccine candidates induce primarily an antibody response to the virus, which is not only ineffective, but potentially deleterious. Currently, there are no available tools to assess the protective T cell responses during infection or post vaccination. The primary objective of this project is to create new informational and diagnostic tools to characterize T cell immunity in DV infection for vaccine validation and potentially develop new, effective and protective vaccine strategies. [unreadable] [unreadable]

IC Name

• Activity

  R43

• Administering IC

  AI

• Application Type

  1

• Direct Cost Amount

• Indirect Cost Amount

• Total Cost

  299998

• Sub Project Total Cost

• ARRA Funded

• CFDA Code

  856

• Ed Inst. Type

• Funding ICs

  NIAID:299998\

• Funding Mechanism

• Study Section

  ZRG1

• Study Section Name

  Special Emphasis Panel

• Organization Name

  IMMUNOTOPE, INC.

• Organization Department

• Organization DUNS

  131080983

• Organization City

  DOYLESTOWN

• Organization State

  PA

• Organization Country

  UNITED STATES

• Organization Zip Code

  18902

• Organization District

  UNITED STATES