Dense life-log health analytics from wearable senors using functional analysis and Riemannian geometry

Information

  • Research Project
  • 10234168
  • ApplicationId
    10234168
  • Core Project Number
    R01GM135927
  • Full Project Number
    5R01GM135927-03
  • Serial Number
    135927
  • FOA Number
    PAR-19-001
  • Sub Project Id
  • Project Start Date
    9/23/2019 - 5 years ago
  • Project End Date
    8/31/2023 - a year ago
  • Program Officer Name
    BRAZHNIK, PAUL
  • Budget Start Date
    9/1/2021 - 3 years ago
  • Budget End Date
    8/31/2022 - 2 years ago
  • Fiscal Year
    2021
  • Support Year
    03
  • Suffix
  • Award Notice Date
    8/24/2021 - 3 years ago
Organizations

Dense life-log health analytics from wearable senors using functional analysis and Riemannian geometry

The growth and acceptance of wearable devices (e.g., accelerometers) and personal technologies (e.g., smartphones), coupled with larger storage capacities, waterproofing, and more unobtrusive wear locations, has made long-term monitoring of behaviors throughout the 24-hour spectrum more feasible. Wearable devices relevant for human activity (e.g., GENEActiv accelerometer) contain several complementary sensors (accelerometers, gyro, heart- rate monitor etc.) and sample at high rates (e.g., 100Hz for accelerometer). These high-sampling rates and the long duration of capture result in life-log data that truly qualifies as multimodal and big time-series data. The challenges and opportunities involved in fully harvesting these types of data, for widely applicable interventions, suggest that an interdisciplinary approach spanning mathematical sciences, signal processing, and health is needed. Our innovation includes the use of functional-data analysis tools to represent and process the dense time-series data. Functional data analysis is then integrated into machine learning and pattern discovery algorithms for activity classification, prediction of attributes, and discovery of new activity classes. We anticipate that the proposed framework will lead to new insights about human activity and its impact on health outcomes. This interdisciplinary project builds on several research activities of the team. Our past work includes: a) new mathematical developments for computing statistics on time-series data viewed as elements of a function-spaces, b) algorithms for activity recognition that integrate the function-space techniques, and c) data from long-term observational studies of human activity from multimodal sensors. The new work we propose addresses the unique mathematical and computational challenges posed by densely multimodal, long-term, densely-sampled Iifelog big-data in a comprehensive framework. The fusion of ideas from human activity modeling, functional-analysis, geometric metrics, and algorithmic machine learning, present unique opportunities for fundamental advancement of the state-of-the-art in objective measurement and quantification of behavioral markers from wearable devices. The proposed approach also brings to fore: a) new mathematical developments of elastic metrics over multi-modal time-series data, b) comparing sequences evolving on different feature manifolds, c) estimation of quasi- periodicities, d) and a new generation of machine-learning and pattern discovery algorithms. The mathematical and algorithmic tools proposed have the potential to significantly advance how wearable data from contemporary devices with high-sampling rates and large storage capabilities are represented, processed, and transformed into accurate inferences about human activity. Wearable devices are becoming more widely adopted in recent years for general health and recreational uses by the broad populace. This research will result in improved algorithms to process the data available from such wearable devices. The long-term goal of the research is to enable personalized home-based physical activity regimens for conditions such as stroke and diabetes.

IC Name
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
  • Activity
    R01
  • Administering IC
    GM
  • Application Type
    5
  • Direct Cost Amount
    248559
  • Indirect Cost Amount
    65579
  • Total Cost
    314138
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    859
  • Ed Inst. Type
  • Funding ICs
    NIGMS:314138\
  • Funding Mechanism
    Non-SBIR/STTR RPGs
  • Study Section
    ZGM1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    ARIZONA STATE UNIVERSITY-TEMPE CAMPUS
  • Organization Department
  • Organization DUNS
    943360412
  • Organization City
    TEMPE
  • Organization State
    AZ
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    852876011
  • Organization District
    UNITED STATES