Dentifrice Compositions

Abstract
Stain-removal, desensitizing, anti-tartar and anti-gingivitis dentifrice compositions. The dentifrices comprise a fluoride agent; an abrasive agent; a proteolytic agent; a foaming agent; a sweetening/flavoring agent; an emulsifying agent; either desensitizing, anti-tartar or anti-gingivitis agents or combinations thereof; and a delivery agent. The dentifrices are visually pleasing and impart a soothing sensation during and after brushing.
Description
DETAILED DESCRIPTION

One embodiment of the present invention is a stain-removal dentifrice composition. The dentifrice comprises a fluoride agent; an abrasive agent; a proteolytic agent; a foaming agent; a sweetening/flavoring agent; an emulsifying agent; and a delivery agent.


Preferably, the fluoride agent comprises sodium fluoride. Preferably, the abrasive agent comprises silica and alumina, each of which is stable in the presence of sodium fluoride. Preferably, the proteolytic agent comprises bromelain. Preferably, the foaming agent comprises saponins. More preferably, the foaming agent comprises yucca saponins or quillaja saponins. More preferably, the foaming agent comprises specially purified quillaja extracts. Preferably, the sweetening agent comprises acesulfame potassium and xylitol. Preferably the emulsifying agent comprises hydrogenated castor oil.


Preferably, the delivery agent comprises soft hollow shapes that are visible to the user and can be loaded with cosmetic and active ingredients, resist dissolution during incorporation and storage in the dentifrice, yet are soft enough to be crushed during brushing. More preferably, the delivery agent comprises Metasomes or Florasomes. Preferably, the Metasomes and Florasomes are loaded with an abrasive polishing agent and a breath-freshening flavoring agent. More preferably, the Metasomes and Florasomes are loaded with a mixture of alumina and menthol. The Metasomes and Florasomes may also be loaded with other flavors, active agents (such as cetylpyridinium chloride, Triclosan, and the like), minerals (such as ortho- or hexametaphosphates for remineralization), vitamins, amino acids, or similar orally-beneficial agents.


The dentifrice of the present invention is characterized by low abrasivity. Low abrasive dentifrices are advantageous because they are not as likely to abrade the soft dentin portion of the tooth and thus will not contribute to gingival recession. This low abrasivity is provided by the combination of the silica and alumina mechanical polishing agents. The inventive dentifrice thus avoids unnecessary removal of tooth structure and because of the use of bromelain, as an effective proteolytic agent, enhances the mechanical stain-removal abilities of silica and alumina. The dentifrice of the present invention also provides a soothing feel to a user's gums and teeth. This feeling is provided in part by the saponins which unlike both sodium lauryl sulfate and cocamidopropyl betaine do not to contribute to mucosal irritation. The hydrating agent, hyaluronic acid, is also included to enhance overall oral health and contribute to oral soothing capabilities. In addition to acting as a sweetening agent, the xylitol used in the present inventive dentifrice provides ancillary benefits including anticariogenic and antibacterial benefits. The dentifrice of the present invention is also characterized by a long shelf life. Unlike dentifrices that do not employ emulsifiers such as hydrogenated castor oil, the inventive dentifrice does not suffer from the problem of synersis that is common with age. The inventive dentifrice is also characterized by a pleasing visual appearance. The appearance is enhanced by the use of Metasomes and Florasomes that are preferably of a color that contrasts with the dentifrice itself and look like crystals. As the Metasomes and Florasomes preferably contain alumina they would be found to be stain-fighting crystals that will gently polish teeth. The Metasomes and Florasomes advantageously resist dissolution during incorporation and storage in the dentifrice, yet are soft enough to be crushed during brushing. By incorporating menthol in the Metasomes and Florasomes, because menthol is solid at room temperature, when brushing the user can experience a tactile “crunching” sensation along with the cooling and long-lasting breath-freshening feeling that menthol affords.


EXAMPLES

Dentifrice compositions were made from the following components:


1—Basic Stain-Fighting Toothpaste (also for individuals suffering from aphthous ulcers):
Part A
Water (aqua)
Bromelain
Part B
Sorbitol
Sodium fluoride
Acesulfame potassium
Methylparaben
Xylitol
Part C
Glycerin
Polyethylene glycol
Sodium carboxymethylcellulose
Part D
Silica, abrasive
Silica, thickening
Alumina
Titanium dioxide
Part E
Hydrogenated castor oil
Flavor (aroma)
Sodium hyaluronate powder
DL-a-tocopheryl acetate (Vitamin E)
Quillaja extract powder
Part F
Metasomes® w 20% alumina & 10% menthol
2—Stain-Fighting Toothpaste with Desensitizing Agents:

add an effective amount of potassium nitrate to Example 1


3—Stain-Fighting Toothpaste with Baking Soda:

add an effective amount of sodium bicarbonate to Example 1


4—Stain-Fighting Toothpaste with Tartar Control Agents:

add an effective amount of sodium tripolyphosphate and tetrasodium pyrophosphate to Example 1


5—Stain-Fighting Toothpaste with Oxygen:

add calcium peroxide to Example 1


6—Stain-Fighting Toothpaste with Desensitizing Agents, Anti-Tartar Agents, Baking Soda and Oxygen:

add an effective amount of potassium nitrate, an effective amount of sodium tripolyphosphate and tetrasodium pyrophosphate, an effective amount of sodium bicarbonate and add calcium peroxide to Example 1


Note that that similar, more restricted, combinations using the Stain-Fighting Toothpaste basic formulation would also be possible.
7—Stain-Fighting Toothpaste with Anti-gingivitis Agents:

add an effective amount of Triclosan or cetylpyridinium chloride to Example 1


8—Stain-Fighting Gel (also for individuals suffering from aphthous ulcers):

remove titanium dioxide and alumina from Example 1


9—Stain-Fighting Gel with Desensitizing Agents:

add an effective amount of potassium nitrate to Example 8


10—Stain-Fighting Gel with Tartar Control Agents:

add an effective amount of sodium tripolyphosphate and tetrasodium pyrophosphate to Example 8


11—Stain-Fighting Gel with Oxygen:

add calcium peroxide to Example 8


12—Stain-Fighting Gel with Desensitizing Agents, Anti-Tartar Agents, Baking Soda and Oxygen:

add an effective amount of potassium nitrate, an effective amount of sodium tripolyphosphate and tetrasodium pyrophosphate, an effective amount of sodium bicarbonate and add calcium peroxide to Example 8


Note that that similar, more restricted, combinations using the Stain-Fighting Toothpaste basic formulation would also be possible.
13—Stain-Fighting Gel with Anti-gingivitis Agents:

add an effective amount of Triclosan or cetylpyridinium chloride to Example 8


The present invention provides a stain-removal dentifrice that has a low abrasivity and does not contribute to mucosal irritation and does not suffer from synersis. Additionally alternate versions the present invention provide for dentifrices that are aesthetically pleasing, offer desensitizing, antitartar, and antigingivitis benefits, can be made with baking soda and combinations of the foregoing benefits and impart a soothing sensation when used while brushing teeth.


Although particular embodiments of this invention have been disclosed herein for purposes of explanation, further modifications or variations thereof will be apparent to those skilled in the art to which this invention pertains. Further, although certain processes have been described by a number of steps in a particular order, the present invention is not limited to any particular order. Thus, the scope of the present invention is not meant to be limited in any way.

Claims
  • 1. A stain removal dentifrice composition comprising an opaque paste containing: at least one fluoride agent;at least one abrasive agent;at least one proteolytic agent;at least one foaming agent;at least one sweetening and breath-freshening flavoring agent;at least one emulsifying agent; andat least one emollient agent,
  • 2. The dentifrice of claim 1 wherein the at least one emollient agent resists dissolution during incorporation and storage in the dentifrice and is soft enough to be crushed during brushing.
  • 3. The dentifrice of claim 1 wherein at least one the emollient agent comprises hollow spheres comprising polyethylene, petrolatum and ethylhexyl palmitate.
  • 4. The dentifrice of claim 1 wherein the at least one emollient agent comprises hollow spheres comprising jojoba esters.
  • 5. The dentifrice of claim 1 wherein the at least one emollient agent further encloses at least one of the elements selected from the group consisting of: active agents, minerals, vitamins, and amino acids.
  • 6. The dentifrice of claim 1 wherein the at least one emollient agent further encloses at least one of the elements selected from the group consisting of: cetylpyridinium chloride and Triclosan.
  • 7. The dentifrice of claim 1 wherein the at least one emollient agent further encloses at least one of the elements selected from the group consisting of: ortho- or hexametaphosphates.
  • 8. A stain-removal and desensitizing dentifrice composition comprising an opaque paste containing the dentifrice of claim 1 with an effective amount of at least one dental desensitizing agent.
  • 9. A stain-removal and desensitizing dentifrice composition comprising an opaque paste containing the dentifrice of claim 1 with an effective amount of anti-tartar agents.
  • 10. The dentifrice of claim 10 where the anti-tartar agents are taken from the group comprised of sodium ripolyphosphate, tetrasodium pyrophosphate, trisodium phosphate, tetrapotassium pyrophosphate and similar phosphate salts.
  • 11. A stain-removal toothpaste with baking soda comprising an opaque paste containing the dentifrice of claim 1 with an effective amount of sodium bicarbonate.
  • 12. A stain-removal and anti-gingivitis dentifrice composition comprising an opaque paste containing the dentifrice of claim 1 with an effective amount of at least one anti-gingivitis agent.
  • 13. The dentifrice of claim 13 where the anti-gingivitis agents are taken from the group comprised of Triclosan and cetylpyridinium chloride.
  • 14. A stain-removal dentifrice with oxygen-releasing ingredients comprising an opaque paste containing the dentifrice of claim 1 with calcium peroxide.
  • 15. A stain-removal dental dentifrice composition comprising a translucent dental gel containing the dentifrice of claim 1.
  • 16. A stain-removal and desensitizing dentifrice composition comprising a translucent dental gel containing the dentifrice of claim 16 with an effective amount of at least one dental desensitizing agent.
  • 17. A stain-removal and desensitizing dentifrice composition comprising a translucent dental gel containing the dentifrice of claim 16 with an effective amount of anti-tartar agents.
  • 18. The dentifrice of claim 18 where the anti-tartar agents are taken from the group comprised of sodium tripolyphosphate, tetrasodium pyrophosphate, trisodium phosphate, tetrapotassium pyrophosphate and similar phosphate salts.
  • 19. A stain-removal and anti-gingivitis dentifrice composition comprising a translucent dental gel containing the dentifrice of claim 16 with an effective amount of at least one anti-gingivitis agent.
  • 20. The dentifrice of claim 20 where the anti-gingivitis agents are taken from the group comprised of Triclosan and cetylpyridimium chloride.
  • 21. A stain-removal dentifrice with oxygen-releasing ingredients comprising a translucent dental gel containing the dentifrice of claim 16 with calcium peroxide.
  • 22. A combination of a stain-removal dentifrices comprising opaque pastes with desensitizing and anti-tartar agents, either with or without baking soda and oxygenating agents.
  • 23. A combination of a stain-removal dentifrices comprising translucent dental gels with desensitizing and anti-tartar agents and oxygenating agents.
  • 24. The translucent gels of claim 24 and opaque pastes with suitable FD&C colorants added for visual effect.
  • 25. Combinations of one or more of a translucent dental gels and one or more of an opaque pastes filled simultaneously into the same tube to impart both visual effect and as a means of delivering combinations of cosmetic and therapeutic benefits.
Provisional Applications (1)
Number Date Country
60843699 Sep 2006 US