Design and directed evolution of an 'Edmanase' enzyme for high-throughput peptide sequencing.

Information

  • Research Project
  • 10259868
  • ApplicationId
    10259868
  • Core Project Number
    R44GM130185
  • Full Project Number
    5R44GM130185-03
  • Serial Number
    130185
  • FOA Number
    PA-19-272
  • Sub Project Id
  • Project Start Date
    9/13/2018 - 7 years ago
  • Project End Date
    8/31/2022 - 3 years ago
  • Program Officer Name
    KREPKIY, DMITRIY
  • Budget Start Date
    9/1/2021 - 4 years ago
  • Budget End Date
    8/31/2022 - 3 years ago
  • Fiscal Year
    2021
  • Support Year
    03
  • Suffix
  • Award Notice Date
    8/31/2021 - 4 years ago
Organizations

Design and directed evolution of an 'Edmanase' enzyme for high-throughput peptide sequencing.

ABSTRACT More accessible and cost-effective technologies for analysis of the proteome would accelerate biological and medical research. The goal of this proposal is to develop enzymatic reagents to enable creation of a highly-scalable digital protein analysis technology. The approach is broadly applicable and greatly improves upon cost, sensitivity, usability, and throughput of current approaches.

IC Name
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
  • Activity
    R44
  • Administering IC
    GM
  • Application Type
    5
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    714694
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    859
  • Ed Inst. Type
  • Funding ICs
    NIGMS:714694\
  • Funding Mechanism
    SBIR-STTR RPGs
  • Study Section
    ZRG1
  • Study Section Name
    Special Emphasis Panel
  • Organization Name
    ENCODIA, INC.
  • Organization Department
  • Organization DUNS
    079752755
  • Organization City
    SAN DIEGO
  • Organization State
    CA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    92121
  • Organization District
    UNITED STATES