Claims
- 1. A method of treating a drug-resistant Plasmodium infection in a patient in need thereof which comprises administering to the patient synergistically effective amounts of chloroquine and desipramine, or pharmaceutically acceptable salts thereof, sufficient to achieve plasma concentrations of 50 to 250 ng/ml of desipramine and 3 to 100 ng/ml of chloroquine.
Parent Case Info
This is a continuation-in-part of application Ser. No. 07/925,703, filed Aug. 4, 1992, which is a continuation-in-part of application Ser. No. 07/725,940, filed Jun. 27, 1991, now abandoned, which is a continuation of application Ser. No. 07/590,437, filed Sep. 26, 1990, now abandoned, which is a continuation of application Ser. No. 07/333,156, filed Apr. 4, 1989, now abandoned, which is a continuation-in-part of application Ser. No. 07/243,524, filed Sep. 12, 1988, now abandoned, which is a continuation-in-part of application Ser. No. 07/183,858, filed Apr. 20, 1988, now abandoned.
Continuations (2)
|
Number |
Date |
Country |
Parent |
590437 |
Sep 1990 |
|
Parent |
333156 |
Apr 1989 |
|
Continuation in Parts (4)
|
Number |
Date |
Country |
Parent |
925703 |
Aug 1992 |
|
Parent |
725940 |
Jun 1991 |
|
Parent |
243524 |
Sep 1988 |
|
Parent |
183858 |
Apr 1988 |
|