DEVELOPMENT OF NEURORECEPTOR SPECIFIC ANTIBODIES

Information

  • Research Project
  • 6312443
  • ApplicationId
    6312443
  • Core Project Number
    N43DA007702
  • Full Project Number
    N43DA007702-000
  • Serial Number
    7702
  • FOA Number
  • Sub Project Id
  • Project Start Date
    3/31/2000 - 24 years ago
  • Project End Date
    -
  • Program Officer Name
  • Budget Start Date
    3/31/2000 - 24 years ago
  • Budget End Date
    9/30/2000 - 24 years ago
  • Fiscal Year
    2000
  • Support Year
  • Suffix
  • Award Notice Date
    -
Organizations

DEVELOPMENT OF NEURORECEPTOR SPECIFIC ANTIBODIES

The contractor intends to develop, in a phase I SBIR contract, polyclonal antibodies designed to be specific for the extracellular domains of subtypes of the following neuroreceptors: metabotropic glutamate, AMPA, NMDA, nicotinic acetylcholine, serotonin, and cannabinoid receptor. Immunogenic epitopes will be identified by way of recombinant receptor segments or by use of synthetic peptides, for stimulation of immune response in rabbits. The antibodies will be used as research probes for determining the composition and localization of neuroreceptor subtypes in-vivo, and for use in biochemical techniques such as immunohistochemistry.

IC Name
NATIONAL INSTITUTE ON DRUG ABUSE
  • Activity
    N43
  • Administering IC
    DA
  • Application Type
    1
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
    99720
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    279
  • Ed Inst. Type
  • Funding ICs
    NIDA:99720\
  • Funding Mechanism
  • Study Section
  • Study Section Name
  • Organization Name
    EIKOS, INC.
  • Organization Department
  • Organization DUNS
  • Organization City
    FRANKLIN
  • Organization State
    MA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    020383034
  • Organization District
    UNITED STATES