DEVELOPMENT OF OPTICAL SENSORS BASED ON A NEW MEMBRANE

Information

  • Research Project
  • 3507829
  • ApplicationId
    3507829
  • Core Project Number
    R44GM036220
  • Full Project Number
    5R44GM036220-03
  • Serial Number
    36220
  • FOA Number
  • Sub Project Id
  • Project Start Date
    9/1/1987 - 37 years ago
  • Project End Date
    12/31/1991 - 33 years ago
  • Program Officer Name
  • Budget Start Date
    9/1/1988 - 36 years ago
  • Budget End Date
    12/31/1991 - 33 years ago
  • Fiscal Year
    1988
  • Support Year
    3
  • Suffix
  • Award Notice Date
    8/12/1988 - 36 years ago

DEVELOPMENT OF OPTICAL SENSORS BASED ON A NEW MEMBRANE

Objectives of the Phase II research are to develop a family of miniature disposable optical sensors for use in the field of medicine to measure pH, pC02 and P02. Single-fiber sensors will be designed to meet the performance specifications for in-vivo measurements in blood, tissue and gastric fluid for clinical and research applications. The unique combination of chemical and optical properties of a new class of acrylic ion-transfer polymers developed by Electrochemical Technology Corp. will be exploited. Fluorescent dyes will be incorporated in polymer membranes that are applied to the ends of polymethyl methacrylate optical fibers by a simple dip and dry technique. Quantitative performance data will be obtained for the sensors and correlated with mathematical models to establish a firm scientific basis for optimization of sensor and system design for specific applications. Potentials for technological innovation include binding of dye molecules in the ion-transfer polymers, developing novel C02 and 02 sensors and optimizing sensors, optics and electronics for high performance. Markets for such sensors in the medical field have been estimated to be on the order of an annual $100 million.

IC Name
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
  • Activity
    R44
  • Administering IC
    GM
  • Application Type
    5
  • Direct Cost Amount
  • Indirect Cost Amount
  • Total Cost
  • Sub Project Total Cost
  • ARRA Funded
  • CFDA Code
    821
  • Ed Inst. Type
  • Funding ICs
  • Funding Mechanism
  • Study Section
    SSS
  • Study Section Name
  • Organization Name
    ELECTROCHEMICAL TECHNOLOGY CORPORATION
  • Organization Department
  • Organization DUNS
  • Organization City
    SEATTLE
  • Organization State
    WA
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    98107
  • Organization District
    UNITED STATES