Development, validation, and application of a CDS ontology to facilitate CDS rules reuse, management, and maintenance in simulated primary care settings.

Information

  • Research Project
  • 10237327
  • ApplicationId
    10237327
  • Core Project Number
    R01GM138589
  • Full Project Number
    5R01GM138589-02
  • Serial Number
    138589
  • FOA Number
    PA-19-056
  • Sub Project Id
  • Project Start Date
    9/1/2020 - 4 years ago
  • Project End Date
    6/30/2025 - 4 months from now
  • Program Officer Name
    RAVICHANDRAN, VEERASAMY
  • Budget Start Date
    7/1/2021 - 3 years ago
  • Budget End Date
    6/30/2022 - 2 years ago
  • Fiscal Year
    2021
  • Support Year
    02
  • Suffix
  • Award Notice Date
    7/12/2021 - 3 years ago
Organizations

Development, validation, and application of a CDS ontology to facilitate CDS rules reuse, management, and maintenance in simulated primary care settings.

Abstract Only 12.7% to 82.9% of the U.S. population receives recommended prevention services, and more specifically, between 70.7% to 91.9% of U.S. children aged 19-35 months receive recommended immunizations (Centers for Disease Control and Prevention, CDC). The utilization of clinical decision support (CDS) can help to increase these rates. Meta-analyses have shown that CDS, as a component of electronic health records (EHRs), is effective in increasing preventive care services. The rules for a CDS involve the knowledge needed to decide a CDS?s behavior in clinical tasks. Continuous rule maintenance is necessary to keep a CDS updated, useful, and at its full potential. Outdated rules can lead to missing alerts for preventive services or even to a patient?s death due to outdated drug-drug interaction alerts. Currently, there are no publicly accessible, reusable, generic, and machine-interpretable CDS rules for immunization schedules. Historically, CDS has been utilized successfully in large academic institutions. In the United States, however, small practices provide healthcare services to a majority of the population, with the volume of physician office visits at about 7.4 times that of hospital visits. In view of rapidly increasing EHR adoption rates in the United States, CDS usage rates have reached 68.5% to 100% in office-based primary care settings, indicating that CDS currently plays an important role in small practices. To be able to regularly update CDS rules is critical to maintaining a CDS. CDS rule management and maintenance have been recognized as challenging in large institutions. Thus, we anticipate that CDS rule management and maintenance will be an obstacle for smaller primary care practices, especially those without in-house IT support. Ontology is the enabling technology of the Semantic Web. Ontology has the potential to improve the interoperability, reusability, and sharability of ontology-based CDS rules, which will reduce duplicate efforts by multiple stakeholders. We also propose to enable primary care providers, especially in settings without in- house IT support, to manage and maintain CDS rules independently. The output of the investigation will be beneficial to small primary care practices in the long term. Our efforts will contribute to more consistent preventive services, including improved immunization recommendation rates for the large population served by these practices. We propose to (1) build and validate an upper-level CDS ontology; (2) develop portable, reusable, and machine-executable CDS rules based on ontology for CDC-recommended immunization schedules; (3) develop implementation scripts for CDS rules; (4) implement CDS rules and evaluate their reuse, use, and maintenance in simulated primary care settings, and (5) revise ontology, CDS rules, and implementation scripts. The long-term goal is to achieve interoperable EHR across platforms seamlessly by utilizing individuals? immunization records. The experience gained from this proposed investigation will provide a critical foundation for our long-term goal and help to solve ?curly braces problem? in the reuse of CDS rules.

IC Name
NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES
  • Activity
    R01
  • Administering IC
    GM
  • Application Type
    5
  • Direct Cost Amount
    225000
  • Indirect Cost Amount
    108510
  • Total Cost
    333510
  • Sub Project Total Cost
  • ARRA Funded
    False
  • CFDA Code
    859
  • Ed Inst. Type
    SCH ALLIED HEALTH PROFESSIONS
  • Funding ICs
    NIGMS:333510\
  • Funding Mechanism
    Non-SBIR/STTR RPGs
  • Study Section
    BCHI
  • Study Section Name
    Biomedical Computing and Health Informatics Study Section
  • Organization Name
    CLEMSON UNIVERSITY
  • Organization Department
    PUBLIC HEALTH & PREV MEDICINE
  • Organization DUNS
    042629816
  • Organization City
    CLEMSON
  • Organization State
    SC
  • Organization Country
    UNITED STATES
  • Organization Zip Code
    296340001
  • Organization District
    UNITED STATES